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β-Hydroxybutyrate enhances astrocyte glutamate uptake through EAAT1 expression regulation
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Transcriptomic changes in the hypothalamus of mice with chronic migraine: Activation of pathways associated with neuropathic inflammation and central sensitization
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SUMOylation modulates mitochondrial dynamics in an in vitro rotenone model of Parkinson's disease
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Knockdown of BMP7 induced oligodendrocyte apoptosis, demyelination and motor function loss
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The neuroprotective effect of short-chain fatty acids against hypoxia-reperfusion injury
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Astrocytes initiate autophagic flux and maintain cell viability after internalizing non-active native extracellular α-synuclein
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Vulnerability of neurofilament-expressing neurons in frontotemporal dementia
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Inhibition of phosphodiesterase 10A mitigates neuronal injury by modulating apoptotic pathways in cold-induced traumatic brain injury
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TAT-PPA1 protects against oxidative stress-induced loss of dopaminergic neurons
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Potential key pathophysiological participant and treatment target in autism spectrum disorder: Microglia
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Sphingosine-1-phosphate receptor 3 promotes neuronal apoptosis via the TNF-α/caspase-3 signaling pathway after acute intracerebral hemorrhage
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The mRNA expression profile of glycine receptor subunits alpha 1, alpha 2, alpha 4 and beta in female and male mice
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Mitochondrial fission and fusion in neurodegenerative diseases:Ca2+ signalling
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Microfluidics in neural extracellular vesicles characterization for early Alzheimer's disease diagnosis
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Glutathione S-transferase: A keystone in Parkinson's disease pathogenesis and therapy
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Microglia-like cells from patient monocytes demonstrate increased phagocytic activity in probable Alzheimer's disease
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Sex-specific cognitive benefits and anti-inflammatory effects of coumestrol pretreatment in transient global cerebral ischemia
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Identifying potential genes driving ferroptosis in the substantia nigra and dopaminergic neurons in Parkinson's disease
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Suppression of BMP signaling restores mitral cell development impaired by FGF signaling deficits in mouse olfactory bulb
Suppression of BMP signaling restores mitral cell development impaired by FGF signaling deficits in mouse olfactory bulb
The olfactory bulb (OB) is found in all vertebrates and is the first relay station of the olfactory information in the bra...
Neuron navigators: A novel frontier with physiological and pathological implications
Neuron navigators: A novel frontier with physiological and pathological implications
The last couple of decades have witnessed a tremendous growth in the field of medical research associated with overall hea...
The elastin-derived peptide (VGVAPG) activates autophagy in neuroblastoma (SH-SY5Y) cells via peroxisome proliferator-activated receptor gamma (PPARγ)
The elastin-derived peptide (VGVAPG) activates autophagy in neuroblastoma (SH-SY5Y) cells via peroxisome proliferator-activated receptor gamma (PPARγ)
Autophagy is a self-degradative process important for balancing the sources of energy and involved in the development of A...
Role of ALS-associated OPTN-K489E mutation in neuronal cell-death regulation
Role of ALS-associated OPTN-K489E mutation in neuronal cell-death regulation
Amyotrophic lateral sclerosis (ALS) affects millions of people worldwide, and till now there is no cure for this disease. ...
Alpha-secretase dependent nuclear localization of the amyloid-β precursor protein-binding protein Fe65 promotes DNA repair
Alpha-secretase dependent nuclear localization of the amyloid-β precursor protein-binding protein Fe65 promotes DNA repair
AbbreviationsADAMA disintegrin and metalloproteaseAICDAPP intracellular domainAPPamyloid-β precursor proteinDAPTN-[N-(3,5-...
The NIDA Avenir award in genetics or epigenetics of substance use disorders
The NIDA Avenir award in genetics or epigenetics of substance use disorders
NIDA's Avenir Program in the Genetics or Epigenetics of Substance Use Disorders (SUDs) was launched to support early stage...
The Npc2Gt(LST105)BygNya mouse signifies pathological changes comparable to human Niemann-Pick type C2 disease
The Npc2Gt(LST105)BygNya mouse signifies pathological changes comparable to human Niemann-Pick type C2 disease
Niemann-Pick type C disease (NP-C) is an autosomal recessive lysosomal storage disease caused by a deficiency in either th...
Satellite glial cell-secreted exosomes after in-vitro oxaliplatin treatment presents a pro-nociceptive effect for dorsal root ganglion neurons and induce mechanical hypersensitivity in naïve mice
Satellite glial cell-secreted exosomes after in-vitro oxaliplatin treatment presents a pro-nociceptive effect for dorsal root ganglion neurons and induce mechanical hypersensitivity in naïve mice
Chemotherapy-induced neuropathic pain (CINP) is a severe side effect of commonly used chemotherapeutics, such as oxaliplat...
CRMP2 conditional knockout changes axonal function and ultrastructure of axons in mice corpus callosum
CRMP2 conditional knockout changes axonal function and ultrastructure of axons in mice corpus callosum
Collapsin response mediator protein 2 (CRMP2) is a member of a protein family, which is highly involved in neurodevelopmen...
The molecular neural mechanism underlying the acceleration of brain aging due to Dcf1 deficiency
The molecular neural mechanism underlying the acceleration of brain aging due to Dcf1 deficiency
Aging is a major risk factor for various types of functional loss as well as highly prevalent chronic or fatal diseases (N...
Recovery of motor function is associated with rescue of glutamate biomarkers in the striatum and motor cortex following treatment with Mucuna pruriens in a murine model of Parkinsons disease
Recovery of motor function is associated with rescue of glutamate biomarkers in the striatum and motor cortex following treatment with Mucuna pruriens in a murine model of Parkinsons disease
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by symptoms that include bradykinesia, ...
Expanded polyQ aggregates interact with sarco-endoplasmic reticulum calcium ATPase and Drosophila inhibitor of apoptosis protein1 to regulate polyQ mediated neurodegeneration in Drosophila
Expanded polyQ aggregates interact with sarco-endoplasmic reticulum calcium ATPase and Drosophila inhibitor of apoptosis protein1 to regulate polyQ mediated neurodegeneration in Drosophila
Unusual expansion of polyQ repeats in certain proteins causes a group of progressive neurodegenerative diseases and Huntin...
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