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Detection of H3F3A K27M or BRAF V600E in liquid biopsies of brain tumor patients as diagnostic and monitoring biomarker: impact of tumor localization and sampling method
Detection of H3F3A K27M or BRAF V600E in liquid biopsies of brain tumor patients as diagnostic and monitoring biomarker: impact of tumor localization and sampling method
Gliomas are the most common brain tumor type in children and adolescents. To date, diagnosis and therapy monitoring for th...
Essential tremor with tau pathology features seeds indistinguishable in conformation from Alzheimer’s disease and primary age-related tauopathy
Essential tremor with tau pathology features seeds indistinguishable in conformation from Alzheimer’s disease and primary age-related tauopathy
Neurodegenerative tauopathies are characterized by the deposition of distinct fibrillar tau assemblies, whose rigid core s...
White matter pathology in FTLD caused by mutations
White matter pathology in FTLD caused by mutations
This work was funded by grants from the Alzheimer’s Association US (016580) and the National Institutes of Health (UAG0639...
Concurrent RB1 and P53 pathway disruption predisposes to the development of a primitive neuronal component in high-grade gliomas depending on MYC-driven EBF3 transcription
Concurrent RB1 and P53 pathway disruption predisposes to the development of a primitive neuronal component in high-grade gliomas depending on MYC-driven EBF3 transcription
The foremost feature of glioblastoma (GBM), the most frequent malignant brain tumours in adults, is a remarkable degree of...
Comparison of the amyloid plaque proteome in Down syndrome, early-onset Alzheimer’s disease, and late-onset Alzheimer’s disease
Comparison of the amyloid plaque proteome in Down syndrome, early-onset Alzheimer’s disease, and late-onset Alzheimer’s disease
Down syndrome (DS) is strongly associated with Alzheimer’s disease (AD) due to APP overexpression, exhibiting Amyloi...
MSH2, MSH6, MLH1, and PMS2 immunohistochemistry as highly sensitive screening method for DNA mismatch repair deficiency syndromes in pediatric high-grade glioma
MSH2, MSH6, MLH1, and PMS2 immunohistochemistry as highly sensitive screening method for DNA mismatch repair deficiency syndromes in pediatric high-grade glioma
Pediatric high-grade glioma (pedHGG) can occur as first manifestation of cancer predisposition syndromes resulting from pa...
Somatic variants in leading to defects in N-glycosylation in mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE)
Somatic variants in leading to defects in N-glycosylation in mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE)
Mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE) is a new histopathological...
fusion driver in primary central nervous system malignancy: case report
fusion driver in primary central nervous system malignancy: case report
Andreiuolo F, Varlet P, Tauziède-Espariat A, Jünger ST, Dörner E et al (2019) Childhood supratentorial ependymomas with YA...
Perivascular glial reactivity is a feature of phosphorylated tau lesions in chronic traumatic encephalopathy
Perivascular glial reactivity is a feature of phosphorylated tau lesions in chronic traumatic encephalopathy
Chronic traumatic encephalopathy (CTE), a neurodegenerative disease associated with repetitive head injuries, is character...
A novel fusion that potentially expands the concept of supratentorial ependymoma, fusion-positive
A novel fusion that potentially expands the concept of supratentorial ependymoma, fusion-positive
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4....
Brain tissue metal concentrations and Alzheimer’s disease neuropathology in total joint arthroplasty patients versus controls
Brain tissue metal concentrations and Alzheimer’s disease neuropathology in total joint arthroplasty patients versus controls
We examined whether total joint arthroplasty (TJA) is associated with increased metal accumulation in the brain and histop...
Microglia aggregates define distinct immune and neurodegenerative niches in Alzheimer's disease hippocampus
Microglia aggregates define distinct immune and neurodegenerative niches in Alzheimer's disease hippocampus
In Alzheimer’s disease (AD), microglia form distinct cellular aggregates that play critical roles in disease progres...
A quantitative Lewy-fold-specific alpha-synuclein seed amplification assay as a progression marker for Parkinson’s disease
A quantitative Lewy-fold-specific alpha-synuclein seed amplification assay as a progression marker for Parkinson’s disease
Misfolded α-synuclein (αSyn) is the hallmark of α-synucleinopathies such as Parkinson’s disease (PD),...
Evidence of COMT dysfunction in the olfactory bulb in Parkinson’s disease
Evidence of COMT dysfunction in the olfactory bulb in Parkinson’s disease
Hyposmia is one of the most prevalent non-motor symptoms of Parkinson’s disease and antecedes motor dysfunction by u...
Parkinson-like wild-type superoxide dismutase 1 pathology induces nigral dopamine neuron degeneration in a novel murine model
Parkinson-like wild-type superoxide dismutase 1 pathology induces nigral dopamine neuron degeneration in a novel murine model
Atypical wild-type superoxide dismutase 1 (SOD1) protein misfolding and deposition occurs specifically within the degenera...
Human brain tissue with MOGHE carrying somatic variants reveal aberrant protein expression and protein loss in the white matter
Human brain tissue with MOGHE carrying somatic variants reveal aberrant protein expression and protein loss in the white matter
Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) is a recently described di...
Characterizing white matter and vascular pathologies in brain donors exposed to repetitive head impacts
Characterizing white matter and vascular pathologies in brain donors exposed to repetitive head impacts
Chronic traumatic encephalopathy (CTE) is a progressive brain disease linked to repetitive head impacts (RHI), often incur...
Hindrances to Tighter Interprofessional Collaboration in Singapore: A Qualitative Study on Primary and Secondary School Counsellors
Hindrances to Tighter Interprofessional Collaboration in Singapore: A Qualitative Study on Primary and Secondary School Counsellors
Interprofessional collaboration (IPC) is defined as the process by which professionals from different roles coordinate the...
“Like an Emotional Trash Can”: An Interview Study of Bhutanese School Guidance Counselors’ Perceived Challenges and Resources
“Like an Emotional Trash Can”: An Interview Study of Bhutanese School Guidance Counselors’ Perceived Challenges and Resources
School counselors are responsible for students’ mental health and their increasingly complex issues. However, little...
Interpersonal Shame, Self-Concealment, and Suicidality for Asian American Adults
Interpersonal Shame, Self-Concealment, and Suicidality for Asian American Adults
This study explored culturally salient predictors of suicide risk for Asian Americans. We examined the relationship betwee...
Exploring the Role of Moral Injury and Meaning Pursuit in the Relationship Between Combat Experience and Well-Being Among Active-Duty Military Members in the United States
Exploring the Role of Moral Injury and Meaning Pursuit in the Relationship Between Combat Experience and Well-Being Among Active-Duty Military Members in the United States
The purpose of this study was to examine the impact and mechanisms of combat exposure on military personnel’s psycho...
A Mixed-Methods Evaluation of a Parent-Directed Training Program for Latine Parents
A Mixed-Methods Evaluation of a Parent-Directed Training Program for Latine Parents
The purpose of this mixed-methods study was to detect the degree of improvement associated with parents’ perceptions...
Happiness Among Malaysian University Students Who Stayed on Campus During Movement Control Order: What Really Matters?
Happiness Among Malaysian University Students Who Stayed on Campus During Movement Control Order: What Really Matters?
The happiness of 245 students who stayed on campus during the COVID-19 pandemic-induced Movement Control Order (MCO) at a ...
Professional Identity Development of Counselor Educators with International Backgrounds through Online Photovoice
Professional Identity Development of Counselor Educators with International Backgrounds through Online Photovoice
Counselor educators with international backgrounds (CEIBs) play critical roles in counselor education by mentoring interna...
Sociocultural and Sociopolitical Elements of School Counselling Professional Identity: A Qualitative Analysis of Palestinian School Counselling Identity
Sociocultural and Sociopolitical Elements of School Counselling Professional Identity: A Qualitative Analysis of Palestinian School Counselling Identity
This study addresses the impact of sociocultural and sociopolitical contexts on the construction of School Counselling Pro...
General Self-efficacy, Career Adaptability, and Hope: a Model Test for University Students in Turkey
General Self-efficacy, Career Adaptability, and Hope: a Model Test for University Students in Turkey
The university years are when individuals evaluate their qualifications, make choices about their careers, and develop the...
Examining the Factor Structure and Psychometric Properties of the Adverse Childhood Experiences Questionnaire Among College Students in the Southeastern United States
Examining the Factor Structure and Psychometric Properties of the Adverse Childhood Experiences Questionnaire Among College Students in the Southeastern United States
The purpose of this study was to evaluate the psychometric properties of the Adverse Childhood Experiences Questionnaire (...
What Counseling Theories Work in China: A Six-Year (2018–2023) Content Analysis of Mental Health Outcome Studies in China
What Counseling Theories Work in China: A Six-Year (2018–2023) Content Analysis of Mental Health Outcome Studies in China
There is an increasing need for efficacious and culturally sensitive mental health services in China. A 6-year (2018–...
Medial prefrontal cortex to nucleus reuniens circuit is critical for performance in an operant delayed nonmatch to position task
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Differential roles of medial/lateral entorhinal cortex in spatial/object memory and contribution to hippocampal functional neuronal organization
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