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Brain acid sphingomyelinase controls addiction-related behaviours in a sex-specific way

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S100A9 protein activates microglia and stimulates phagocytosis, resulting in synaptic and neuronal loss

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Current safety recommendations for handling mouse and human αsynuclein pre-formed fibrils

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Retraction Notice to “Differential effects of immunotherapy with antibodies targeting α-synuclein oligomers and fibrils in a transgenic model of synucleinopathy” [Neurobiology of Disease 104 (2017) 85–96]

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The impact of gut microbiota on the occurrence, treatment, and prognosis of ischemic stroke

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Effects of trace element dysregulation on brain structure and function in spinocerebellar Ataxia type 3

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Attenuated neurotoxicity after repeated methamphetamine binges linked to dopamine transporter (DAT) decline

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Long-term exposure to anti-GluA3 antibodies triggers functional and structural changes in hippocampal neurons

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Impairment in the homeostatic recruitment of layer 5/6 neurons following whisker stimulation in Fmr1 KO mice

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Abnormal neuronal activity in the subthalamic nucleus contributes to dysarthria in patients with Parkinson's disease

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Peripheral blood immune cells from individuals with Parkinson's disease or inflammatory bowel disease share deficits in iron storage and transport that are modulated by non-steroidal anti-inflammatory drugs

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B cells upregulate NMDARs, respond to extracellular glutamate, and express mature BDNF to protect the brain from ischemic injury

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Insights into dentatorubral-pallidoluysian atrophy from a new Drosophila model of disease

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A missense variant in DEPDC5 resulted in abnormal morphology and increased seizure susceptibility and mortality through regulating mTOR signaling

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Deficits in taste-guided behaviors and central processing of taste in the transgenic TDP-43Q331K mouse model of frontotemporal dementia

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WTAP suppresses STAT3 via m6A methylation to regulate autophagy and inflammation in central nervous system injury

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Lack of neuroprotection after systemic administration of the soluble TNF inhibitor XPro1595 in an rAAV6-α-Syn + PFFs-induced rat model for Parkinson's disease

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iPSC models of mitochondrial diseases

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An unraveled mystery: What's the role of brain sphingolipids in neurodegenerative and psychiatric disorders

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Glycosphingolipids in neurodegeneration – Molecular mechanisms, cellular roles, and therapeutic perspectives

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Harmonization of CSF and imaging biomarkers for Alzheimer's disease: Need and practical applications for genetics studies and preclinical classification

In Alzheimer's disease (AD) research, cerebrospinal fluid (CSF) Amyloid beta (Aβ), Tau and pTau are the most accepted and ...

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The effects of P2 segment of posterior cerebral artery to thalamus blood supply pattern on gait in cerebral small vessel disease: A 7 T MRI based study

Keywords7 T MRIThalamusCerebral small vessel diseasePosterior cerebral arteryGaitAbbreviationsAAL3automated anatomical lab...

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Differential profiles of serum cytokines in Parkinson's disease according to disease duration

ObjectiveNeurodegeneration and neuroinflammation are two intertwined mechanisms contributing to the pathophysiology of Par...

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PI3K signaling promotes formation of lipid-laden foamy macrophages at the spinal cord injury site

After spinal cord injury (SCI), infiltrating macrophages undergo excessive phagocytosis of myelin and cellular debris, for...

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Predicting neurodegeneration from sleep related biofluid changes

Sleep-wake disturbances are common in neurodegenerative diseases and may occur years before the clinical diagnosis, potent...

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Antisense oligonucleotide-mediated disruption of HTT caspase-6 cleavage site ameliorates the phenotype of YAC128 Huntington disease mice

KeywordsHuntington diseaseYAC128 miceAntisense oligonucleotidesCaspase-6RNA splicingRNA sequence analysisMRIAbbreviationsa...

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Proteomic analysis of X-linked dystonia parkinsonism disease striatal neurons reveals altered RNA metabolism and splicing

KeywordsNeurodegenerationX-linked dystonia parkinsonism diseaseInduced pluripotent stem cellsMedium spiny neuronsQuantitat...

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External segment of the globus pallidus in health and disease: Its interactions with the striatum and subthalamic nucleus

KeywordsExternal segment of the globus pallidusStriatumSubthalamic nucleusParkinson's diseaseMovement disordersDeep brain ...

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Characterisation and prion transmission study in mice with genetic reduction of sporadic Creutzfeldt-Jakob disease risk gene Stx6

KeywordsPrion diseaseCreutzfeldt-Jakob diseaseSNARESyntaxin-6Incubation periodAbbreviationssCJDsporadic Creutzfeldt-Jakob ...

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Ganglioglioma cells potentiate neuronal network synchronicity and elicit burst discharges via released factors

Gangliogliomas (GGs) represent the most frequent glioneuronal tumor entity associated with chronic recurrent seizures; rar...

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