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Discovery of structurally diverse sesquiterpenoids from isolated from feces and their antifungal activities
Discovery of structurally diverse sesquiterpenoids from isolated from feces and their antifungal activities
Thirty-six structurally diverse sesquiterpenoids, including caryolanes (1–12), germacranes (13–16), isodaucane...
Diterpene chemical space of Briq. aerial part
Diterpene chemical space of Briq. aerial part
The Plectranthinae clade, which includes genera such as Plectranthus, Ocimum, and Aeollanthus, is well known for its diver...
Euchrestifolines A–O, fifteen novel carbazole alkaloids with potent anti-ferroptotic activity from
Euchrestifolines A–O, fifteen novel carbazole alkaloids with potent anti-ferroptotic activity from
Fifteen novel carbazole alkaloids, euchrestifolines A–O (1–15), were obtained from Murraya euchrestifolia. The...
Widely targeted metabolomics analysis reveals differences in volatile metabolites among four species
Widely targeted metabolomics analysis reveals differences in volatile metabolites among four species
Angelica L. has attracted global interest for its traditional medicinal uses and commercial values. However, few studies h...
Phytochemical fingerprinting of phytotoxins as a cutting-edge approach for unveiling nature’s secrets in forensic science
Phytochemical fingerprinting of phytotoxins as a cutting-edge approach for unveiling nature’s secrets in forensic science
The integration of phytochemistry into forensic science has emerged as a groundbreaking frontier, providing unprecedented ...
Unveiling the mechanism of action of a novel natural dual inhibitor of SARS-CoV-2 Mpro and PLpro with molecular dynamics simulations
Unveiling the mechanism of action of a novel natural dual inhibitor of SARS-CoV-2 Mpro and PLpro with molecular dynamics simulations
In the twenty-first century, we have witnessed multiple coronavirus pandemics. Despite declining SARS-CoV-2 cases, continu...
New semisynthetic α-glucosidase inhibitor from a doubly-chemically engineered extract
New semisynthetic α-glucosidase inhibitor from a doubly-chemically engineered extract
Chemically engineered extracts represent a promising source of new bioactive semi-synthetic molecules. Prepared through di...
Discovery of a parallel family of euglenatide analogs in
Discovery of a parallel family of euglenatide analogs in
The euglenatides are a family of hybrid polyketide-nonribosomal peptides produced by the unicellular algae Euglena gracili...
Dibohemamines I–O from sp. GZWMJZ-662, an endophytic actinomycete from the medicinal and edible plant Thunb.
Dibohemamines I–O from sp. GZWMJZ-662, an endophytic actinomycete from the medicinal and edible plant Thunb.
A chemical investigation of Streptomyces sp. GZWMJZ-662, an endophytic actinomycete isolated from Houttuynia cordata Thunb...
Novel -clerodane diterpenoids from and their anti-ferroptosis effect
Novel -clerodane diterpenoids from and their anti-ferroptosis effect
Teucrifarides A–D (1–4), four previously unreported neo-clerodane-type diterpenoids, combined with sixteen kno...
Metabolomic and transcriptomic analyses revealed potential mechanisms of Retz. in alleviating cerebral ischemia–reperfusion injury via Wnt/β-catenin pathway modulation
Metabolomic and transcriptomic analyses revealed potential mechanisms of Retz. in alleviating cerebral ischemia–reperfusion injury via Wnt/β-catenin pathway modulation
Anchusa italica Retz. (AIR), a traditional herbal remedy, is commonly applied in managing heart and brain disorders. Howev...
The need for smart microalgal bioprospecting
The need for smart microalgal bioprospecting
Microalgae’s adaptability and resilience to Earth’s diverse environments have evolved these photosynthetic mic...
Essential oil and furanosesquiterpenes from myrrh oleo-gum resin: a breakthrough in mosquito vector management
Essential oil and furanosesquiterpenes from myrrh oleo-gum resin: a breakthrough in mosquito vector management
Mosquitoes (Diptera: Culicidae) are vectors of various pathogens of public health concern and replacing conventio...
Marine natural products as a source of novel anticancer drugs: an updated review (2019–2023)
Marine natural products as a source of novel anticancer drugs: an updated review (2019–2023)
Marine natural products have long been recognized as a vast and diverse source of bioactive compounds with potential thera...
Design, synthesis and biological evaluation of buthutin derivatives as cardioprotective agents
Design, synthesis and biological evaluation of buthutin derivatives as cardioprotective agents
Natural products are the important sources in cardiovascular drug development. In this study, twenty-nine buthutin derivat...
Structure–function insights of natural polysaccharides: advances in biosynthesis and functional food applications
Structure–function insights of natural polysaccharides: advances in biosynthesis and functional food applications
Ganoderma polysaccharides (GPs), derived from various species of the Ganoderma genus, exhibit diverse bioactivities, inclu...
Advanced RPL19-TRAP-seq method reveals mechanism of action of bioactive compounds
Advanced RPL19-TRAP-seq method reveals mechanism of action of bioactive compounds
Natural products play a crucial role in new drug development, but their druggability is often limited by uncertain molecul...
Emestrin-type epipolythiodioxopiperazines from with cytotoxic activities by regulating PI3K/AKT and mitochondrial apoptotic pathways
Emestrin-type epipolythiodioxopiperazines from with cytotoxic activities by regulating PI3K/AKT and mitochondrial apoptotic pathways
Five novel emestrin-type epipolythiodioxopiperazines (ETPs), prenylemestrins C−G (1–5), along with two known E...
Newly isolated terpenoids (covering 2019–2024) from species and their potential for the discovery of novel antimicrobials
Newly isolated terpenoids (covering 2019–2024) from species and their potential for the discovery of novel antimicrobials
The rapid emergence of drug-resistant microbial pathogens has posed challenges to global health in the twenty-first centur...
Green Synthesis of CuFe2O4 Nanoparticles Using Natural Extracts: Structural, Optical, and Magnetic Studies
Green Synthesis of CuFe2O4 Nanoparticles Using Natural Extracts: Structural, Optical, and Magnetic Studies
There has been growing interest in green synthetic methods for nanoscale materials based on natural extracts, as they have...
The Effect of Phase Changes on Optoelectronic Properties of Lead-Free CsSnI3 Perovskites
The Effect of Phase Changes on Optoelectronic Properties of Lead-Free CsSnI3 Perovskites
First-principles calculations were carried out within the framework of density functional theory to investigate the influe...
Carbon Nanotubes as Emerging Field Emitters: Influencing Factors and Remedies
Carbon Nanotubes as Emerging Field Emitters: Influencing Factors and Remedies
In vacuum and display electronics, field emission (FE) electron sources are becoming increasingly common because of their ...
A Comprehensive Study on the Impact of Aluminum Doping on X-ray Diffraction Peak Profile Analysis, Structural, Morphological, and Optical Properties of ZnO Nanoparticles Synthesized by Sol–Gel Auto-Combustion
A Comprehensive Study on the Impact of Aluminum Doping on X-ray Diffraction Peak Profile Analysis, Structural, Morphological, and Optical Properties of ZnO Nanoparticles Synthesized by Sol–Gel Auto-Combustion
The effect of aluminum doping on the structural, morphological and optical properties of Zn1-xAlxO (0 ≤&...
Structural, Magnetic, Optical, and Dielectric Properties of Nd3+ Ion-Doped Mg0.5Zn0.5Fe2−xNdxO4 Nanoparticles
Structural, Magnetic, Optical, and Dielectric Properties of Nd3+ Ion-Doped Mg0.5Zn0.5Fe2−xNdxO4 Nanoparticles
We report a facile synthesis of Mg0.5Zn0.5Fe2−xNdxO4, (x = 0, 0.025, 0.050, 0.075, 0.1) employing ...
High-Performance Supercapacitor Electrode Materials: Cu/MnXx (X = O, S, C)-rGO Nanocomposites Derived from CuMn-BTC Metal–Organic Framework
High-Performance Supercapacitor Electrode Materials: Cu/MnXx (X = O, S, C)-rGO Nanocomposites Derived from CuMn-BTC Metal–Organic Framework
Electrochemical supercapacitors, given their high power density and excellent cycling stability, have broad applications f...
Synthesis, Characterization, and Supercapacitor Performance of Fe-MOF Nanorods for Energy Storage Applications
Synthesis, Characterization, and Supercapacitor Performance of Fe-MOF Nanorods for Energy Storage Applications
Metal–organic frameworks (MOFs) are highly desirable constituents in the field of supercapacitors due to their abili...
Influence of a Copper Layer on the Functional Behaviour of a Cadmium Telluride Solar Cell Processed via Thermal Evaporation
Influence of a Copper Layer on the Functional Behaviour of a Cadmium Telluride Solar Cell Processed via Thermal Evaporation
Cadmium telluride (CdTe) has emerged as a popular option for the solar cell industry because of its favourable optical and...
A Novel Mesoporous Al2O3@Graphene Composite as Photocatalyst for Organic Pollutant Removal
A Novel Mesoporous Al2O3@Graphene Composite as Photocatalyst for Organic Pollutant Removal
In this work, a microwave irradiation approach was employed to synthesize Al2O3 nanoparticles uniformly adhered onto graph...
Preventive and therapeutic effects of ephedrine alkaloids-free Ephedra Herb extract on paclitaxel-induced neuropathic pain
Preventive and therapeutic effects of ephedrine alkaloids-free Ephedra Herb extract on paclitaxel-induced neuropathic pain
Currently, there are no effective prophylactic or therapeutic drugs for the treatment of paclitaxel (PTX)-induced peripher...
New sesquiterpenes from the soft coral Litophyton arboreum
New sesquiterpenes from the soft coral Litophyton arboreum
Two new sesquiterpenes; 8α,11-dihydroxy-β-cyperon (2), and 5-epi-7α-hydroxy-( +)-oplopanone (3), were...
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