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Noise-induced cochlear synaptopathy in C57BL/6 N mice as a function of trauma strength: ribbons are more vulnerable than postsynapses
Noise-induced cochlear synaptopathy in C57BL/6 N mice as a function of trauma strength: ribbons are more vulnerable than postsynapses
Noise-induced cochlear synaptopathy is characterized by irreversible loss of synapses between inner hair cells (IHCs) and ...
A novel KCNC3 gene variant in the voltage-dependent Kv3.3 channel in an atypical form of SCA13 with dominant central vertigo
A novel KCNC3 gene variant in the voltage-dependent Kv3.3 channel in an atypical form of SCA13 with dominant central vertigo
Potassium channel mutations play an important role in neurological diseases, such as spinocerebellar ataxia (SCA). SCA is ...
Loss of C1q alters the auditory brainstem response
Loss of C1q alters the auditory brainstem response
Neural circuits in the auditory brainstem compute interaural time and intensity differences used to determine the location...
Editorial: Neuromodulation technology: advances in optics and acoustics
It is estimated that about 43.3 million people are blind and 295 million with moderate to severe visual impairment worldwi...
Therapeutic potential of mesenchymal stem cell-derived exosomes and miRNAs in neuronal regeneration and rejuvenation in neurological disorders: a mini review
Therapeutic potential of mesenchymal stem cell-derived exosomes and miRNAs in neuronal regeneration and rejuvenation in neurological disorders: a mini review
Mesenchymal stem cells (MSCs) have gained considerable attention in the field of regenerative medicine due to their abilit...
Mathematical models of C-type and N-type inactivating heteromeric voltage gated potassium channels
Mathematical models of C-type and N-type inactivating heteromeric voltage gated potassium channels
Voltage gated potassium channels can be composed of either four identical, or different, pore-forming protein subunits. Wh...
Organoid intelligence for developmental neurotoxicity testing
Organoid intelligence for developmental neurotoxicity testing
The increasing prevalence of neurodevelopmental disorders has highlighted the need for improved testing methods to determi...
Retraction: Santacruzamate A Ameliorates AD-Like Pathology by Enhancing ER Stress Tolerance Through Regulating the Functions of KDELR and Mia40-ALR in vivo and in vitro
Retraction: Santacruzamate A Ameliorates AD-Like Pathology by Enhancing ER Stress Tolerance Through Regulating the Functio...
The impact of maternal anti-inflammatory drugs on surgical anesthesia-induced neuroinflammation and cognitive impairment in offspring mice
The impact of maternal anti-inflammatory drugs on surgical anesthesia-induced neuroinflammation and cognitive impairment in offspring mice
BackgroundThe impact of maternal surgery combined with general anesthesia on neuroinflammation and the development of lear...
Alzheimer’s disease induced neurons bearing PSEN1 mutations exhibit reduced excitability
Alzheimer’s disease induced neurons bearing PSEN1 mutations exhibit reduced excitability
Alzheimer’s disease (AD) is a devastating neurodegenerative condition that affects memory and cognition, characterized by ...
Deprivation of visual input alters specific subset of inhibitory neurons and affect thalamic afferent terminals in V1 of rd1 mouse
Deprivation of visual input alters specific subset of inhibitory neurons and affect thalamic afferent terminals in V1 of rd1 mouse
Retinitis Pigmentosa (RP) is a heterogenous group of inherited disorder, and its progression not only affects the retina b...
ALS-like pathology diminishes swelling of spinal astrocytes in the SOD1 animal model
ALS-like pathology diminishes swelling of spinal astrocytes in the SOD1 animal model
Astrocytes are crucial for the functioning of the nervous system as they maintain the ion homeostasis via volume regulatio...
Quantitative, real-time imaging of spreading depolarization-associated neuronal ROS production
Quantitative, real-time imaging of spreading depolarization-associated neuronal ROS production
Spreading depolarization (SD) causes a massive neuronal/glial depolarization, disturbs ionic homeostasis and deranges neur...
Manipulation of DHPS activity affects dendritic morphology and expression of synaptic proteins in primary rat cortical neurons
Manipulation of DHPS activity affects dendritic morphology and expression of synaptic proteins in primary rat cortical neurons
Deoxyhypusine synthase (DHPS) catalyzes the initial step of hypusine incorporation into the eukaryotic initiation factor 5...
A novel loss-of-function KCNB1 gene variant in a twin with global developmental delay and seizures
A novel loss-of-function KCNB1 gene variant in a twin with global developmental delay and seizures
Human voltage-gated potassium (Kv) channels are expressed by a 40-member gene family that is essential for normal electric...
The role of ferroptosis in neurodegenerative diseases
The role of ferroptosis in neurodegenerative diseases
Ferroptosis represents an iron− and lipid peroxidation (LPO)-mediated form of regulated cell death (RCD). Recent evidence ...
Editorial: Extracellular vesicles: emerging roles in the aged and neurodegenerative brain
Over the past few decades, central nervous system (CNS) and peripheral nervous system (PNS) secreted nanosized extracellul...
The impact of COVID-19 on accelerating of immunosenescence and brain aging
1 Introduction The unprecedented COVID-19 pandemic claimed millions of lives in a short period, and its threat continues...
Müller cells and retinal angiogenesis: critical regulators in health and disease
1 Introduction The vascular system is essential for delivering oxygen, nutrients, and metabolic precursors, transporting...
The effects of locus coeruleus ablation on mouse brain volume and microstructure evaluated by high-field MRI
1 Introduction The locus coeruleus (LC) is a small nucleus located in the pons. Acting as the principal source of noradre...
Acute stress modulates hippocampal to entorhinal cortex communication
Acute stress modulates hippocampal to entorhinal cortex communication
Feed-forward inhibition is vital in the transfer and processing of synaptic information within the hippocampal–entorhinal ...
Corrigendum: Spatiotemporal analysis of 3D human iPSC-derived neural networks using a 3D multi-electrode array
Corrigendum: Spatiotemporal analysis of 3D human iPSC-derived neural networks using a 3D multi-electrode array
Corrigendum on: Lam D, Enright HA, Cadena J, George VK, Soscia DA, Tooker AC, Triplett M, Peters SKG, Karande P, Ladd A, B...
Biomarkers associated with the pathogenesis of Alzheimer’s disease
Biomarkers associated with the pathogenesis of Alzheimer’s disease
Alzheimer’s disease (AD) is a progressive degenerative neurological illness with insidious onset. Due to the complexity of...
Diencephalic organoids – A key to unraveling development, connectivity, and pathology of the human diencephalon
Diencephalic organoids – A key to unraveling development, connectivity, and pathology of the human diencephalon
The diencephalon, an integral component of the forebrain, governs a spectrum of crucial functions, ranging from sensory pr...
Different responses of mice and rats hippocampus CA1 pyramidal neurons to in vitro and in vivo-like inputs
Different responses of mice and rats hippocampus CA1 pyramidal neurons to in vitro and in vivo-like inputs
The fundamental role of any neuron within a network is to transform complex spatiotemporal synaptic input patterns into in...
MicroRNA as potential biomarker for severity, progression, and therapeutic monitoring in animal models of limb-girdle muscular dystrophy: a systematic review
MicroRNA as potential biomarker for severity, progression, and therapeutic monitoring in animal models of limb-girdle muscular dystrophy: a systematic review
Limb-girdle muscular dystrophies (LGMD) constitute a heterogeneous group of neuromuscular disorders in which there are alt...
Astrocytes control hippocampal synaptic plasticity through the vesicular-dependent release of D-serine
Astrocytes control hippocampal synaptic plasticity through the vesicular-dependent release of D-serine
Astrocytes, the most abundant glial cells in the central nervous system (CNS), sense synaptic activity and respond through...
Presynaptic GABAB receptors inhibit vomeronasal nerve transmission to accessory olfactory bulb mitral cells
Presynaptic GABAB receptors inhibit vomeronasal nerve transmission to accessory olfactory bulb mitral cells
Vomeronasal sensory neurons (VSNs) recognize pheromonal and kairomonal semiochemicals in the lumen of the vomeronasal orga...
Selective oxytocin receptor activation prevents prefrontal circuit dysfunction and social behavioral alterations in response to chronic prefrontal cortex activation in male rats
Selective oxytocin receptor activation prevents prefrontal circuit dysfunction and social behavioral alterations in response to chronic prefrontal cortex activation in male rats
IntroductionSocial behavioral changes are a hallmark of several neurodevelopmental and neuropsychiatric conditions, nevert...
Human motor neurons derived from induced pluripotent stem cells are susceptible to SARS-CoV-2 infection
Human motor neurons derived from induced pluripotent stem cells are susceptible to SARS-CoV-2 infection
IntroductionCOVID-19 typically causes Q7 respiratory disorders, but a high proportion of patients also reports neurologica...
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