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Expanding treatment indications in chronic hepatitis B: Should we treat all patients?
Expanding treatment indications in chronic hepatitis B: Should we treat all patients?
Nucleos(t)ide analogues (NUCs) are first-line agents for chronic hepatitis B (CHB). Current guidelines provide recommendat...
Predictive value of neutrophil-to-lymphocyte ratio in recurrent HCC after repeat hepatectomy or salvage liver transplantation
Predictive value of neutrophil-to-lymphocyte ratio in recurrent HCC after repeat hepatectomy or salvage liver transplantation
Hepatocellular carcinoma (HCC) is the most prevalent type of primary liver cancer, characterized by a high rate of recurre...
The Asian Pacific association for the study of the liver clinical practice guidelines for the diagnosis and management of metabolic dysfunction-associated fatty liver disease
The Asian Pacific association for the study of the liver clinical practice guidelines for the diagnosis and management of metabolic dysfunction-associated fatty liver disease
Metabolic dysfunction-associated fatty liver disease (MAFLD) affects over one-fourth of the global adult population and is...
Acute kidney injury stage 1a increases mortality of patients with cirrhosis: a prospective multicenter cohort study
Acute kidney injury stage 1a increases mortality of patients with cirrhosis: a prospective multicenter cohort study
Acute kidney injury is a severe complication of cirrhosis. However, the impact of mild decreases in renal function is cont...
Analysis of risk factors for immune checkpoint inhibitor-associated liver injury: a retrospective analysis based on clinical study and real-world data
Analysis of risk factors for immune checkpoint inhibitor-associated liver injury: a retrospective analysis based on clinical study and real-world data
Immune-mediated hepatotoxicity (IMH) induced by immune checkpoint inhibitors (ICIs) can lead to fatal outcomes. Exploring ...
The benefit of conversion therapy for patients with unresectable hepatocellular carcinoma receiving atezolizumab plus bevacizumab using newly established oncological resectability criteria in Japan
The benefit of conversion therapy for patients with unresectable hepatocellular carcinoma receiving atezolizumab plus bevacizumab using newly established oncological resectability criteria in Japan
This study aimed to investigate the changes in oncological resection status in patients with unresectable hepatocellular c...
Impact of plasma exchange on bilirubin reduction and neurological impairment in infantile acute liver failure
Impact of plasma exchange on bilirubin reduction and neurological impairment in infantile acute liver failure
Conflict of interest The authors have no relevant financial or non-...
Safety of tenofovir alafenamide in the context of hyperlipidemia and cardiovascular diseases: a nationwide analysis
Safety of tenofovir alafenamide in the context of hyperlipidemia and cardiovascular diseases: a nationwide analysis
Despite numerous small-scale studies, the correlation between tenofovir alafenamide fumarate (TAF) and hyperlipidemia rema...
Patterns and outcomes of early and late recurrence after hepatectomy for hepatocellular carcinoma with microvascular invasion: a multicenter study in China
Patterns and outcomes of early and late recurrence after hepatectomy for hepatocellular carcinoma with microvascular invasion: a multicenter study in China
A few studies focus on the long-term outcomes and surveillance strategies for patients with hepatocellular carcinoma (HCC)...
Global prevalence, metabolic characteristics, and outcomes of lean-MAFLD: a systematic review and meta-analysis
Global prevalence, metabolic characteristics, and outcomes of lean-MAFLD: a systematic review and meta-analysis
Metabolic Dysfunction-Associated Fatty Liver disease (MAFLD) among lean individuals is increasingly recognized. We aimed t...
Efficacy of measuring natural killer-activating receptor ligands to predict the pathogenesis of metabolic dysfunction-associated steatotic liver disease
Efficacy of measuring natural killer-activating receptor ligands to predict the pathogenesis of metabolic dysfunction-associated steatotic liver disease
The proportion of non-B/non-C hepatocellular carcinoma cases is increasing, and the principal cause is metabolic dysfuncti...
Explainable attention-enhanced heuristic paradigm for multi-view prognostic risk score development in hepatocellular carcinoma
Explainable attention-enhanced heuristic paradigm for multi-view prognostic risk score development in hepatocellular carcinoma
Existing prognostic staging systems depend on expensive manual extraction by pathologists, potentially overlooking latent ...
Variceal band ligation and carvedilol: together forever, or not?
Variceal band ligation and carvedilol: together forever, or not?
We extend our congratulations to Tevethia et al for their recently published ‘CAVARLY trial’, which suggests the combinati...
Extending inflamed-class signature to predict immune checkpoint inhibitor-based combination therapy in hepatocellular carcinoma
Extending inflamed-class signature to predict immune checkpoint inhibitor-based combination therapy in hepatocellular carcinoma
Recently, we were intrigued by a recent study by Montironi et al,1 in which they discovered that an inflamed subclass in h...
Environmental and healthcare trade-offs between single-use and reusable gastroscopes
Environmental and healthcare trade-offs between single-use and reusable gastroscopes
We would like to offer some critical observations regarding the recent article published on the environmental impact of si...
Unravelling lipidomic disruptions across multiple tissues in Chd8-mutant ASD mice through integration of lipidomics and single-cell transcriptomics
Unravelling lipidomic disruptions across multiple tissues in Chd8-mutant ASD mice through integration of lipidomics and single-cell transcriptomics
With great interest, we read the article by Lou et al,1 who reported deviated gut microbiota in children with autism spect...
High-risk varices in patients with Child-Pugh-Turcotte B and C: consider band ligation with carvedilol for preventing first variceal bleeding, especially in patients with MASLD-associated cirrhosis
High-risk varices in patients with Child-Pugh-Turcotte B and C: consider band ligation with carvedilol for preventing first variceal bleeding, especially in patients with MASLD-associated cirrhosis
International guidelines recommend that primary prophylaxis of varices in patients with cirrhosis be either non-selective ...
Is the biogeography of the mucosa-associated microbiota a key factor affecting primary sclerosing cholangitis disease course and treatment?
Is the biogeography of the mucosa-associated microbiota a key factor affecting primary sclerosing cholangitis disease course and treatment?
We have read with interest the contribution by Bedke et al,1 reporting changes in the stool microbiota associated with pri...
Targeting TL1A and DR3: the new frontier of anti-cytokine therapy in IBD
Targeting TL1A and DR3: the new frontier of anti-cytokine therapy in IBD
TNF-like cytokine 1A (TL1A) and its functional receptor, death-domain receptor 3 (DR3), are members of the TNF and TNFR su...
Landscape of B lymphocytes and plasma cells in digestive tract carcinomas
Authors Konstantina Dimopoulou, ...
Diagnostic approach to patients with suspected motility disorders: one size does not fit all
Authors Theodoros Voulgaris, ...
Peroral endoscopic myotomy (Z-POEM) versus flexible endoscopic septotomy (FES) for treatment of Zenker’s diverticulum: does either make the cut? A systematic review and meta-analysis of outcomes
Authors Sahib Singh, ...
Simethicone with or without N-acetylcysteine as premedication in esophagogastroduodenoscopy: a systematic review and meta-analysis
Authors Caroline Tanadi, ...
Early rebleeding rate following endoscopic treatment of colonic diverticular bleeding: a systematic review and meta-analysis
Authors Isha Delaleeuwe, ...
Impact of pericarditis on cardiovascular complications and healthcare utilization in patients with inflammatory bowel disease: a National Inpatient Sample study
Authors Ayushi Garg, ...
Endoscopic management of ileal pouch–anal anastomosis strictures: meta-analysis and systematic literature review
Authors Parth Patel, ...
Diverticulosis and neoplastic lesions in screening colonoscopy: a large, multicenter study
Authors Paolo Fedeli, ...
Gastrointestinal cancer incidence after lung transplantation in sarcoidosis patients
Authors Graham Saeed, ...
The treatment interventions and targets of cancer cachexia research during the past decade: a systematic review of the literature
Authors Panagiotis Filis, ...
Validation of gender-equity model for liver allocation (GEMA) and its sodium variant (GEMA-Na) in candidates for liver transplantation
Authors Magdalini Adamantou, ...
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