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Author Correction: The novel sophoridine derivate IMB-HDC induced lessened phosphorylation of STAT5a at 694 and 780 and promoted DNA breakage and cell apoptosis via blocking STAT5a nuclear translocation
Author Correction: The novel sophoridine derivate IMB-HDC induced lessened phosphorylation of STAT5a at 694 and 780 and promoted DNA breakage and cell apoptosis via blocking STAT5a nuclear translocation
Author notesThese authors contributed equally: Wu-li Zhao, Yan XingAuthors and AffiliationsKey Laboratory of Antibiotic Bi...
MMP-9 inhibitor SB-3CT improves neurological outcomes in ischemic stroke mice by modulation of astrocytic lipid metabolism
MMP-9 inhibitor SB-3CT improves neurological outcomes in ischemic stroke mice by modulation of astrocytic lipid metabolism
The acute phase of ischemic stroke is marked by a surge in matrix metalloproteinase-9 (MMP-9) activity. While integral to ...
CYP2A6 suppresses hepatocellular carcinoma via inhibiting SRC/Wnt/β-Catenin pathway
CYP2A6 suppresses hepatocellular carcinoma via inhibiting SRC/Wnt/β-Catenin pathway
Patients with hepatocellular carcinoma (HCC) at advanced stages face limited treatment options, highlighting the urgent ne...
Epigenetic regulation of iron metabolism and ferroptosis in Parkinson’s disease: Identifying novel epigenetic targets
Epigenetic regulation of iron metabolism and ferroptosis in Parkinson’s disease: Identifying novel epigenetic targets
Parkinson’s disease (PD) is a neurodegenerative disease, and emerging evidence has shown that iron deposition, ferro...
An efficient deep learning-based strategy to screen inhibitors for GluN1/GluN3A receptor
An efficient deep learning-based strategy to screen inhibitors for GluN1/GluN3A receptor
The GluN1/GluN3A receptor, a unique excitatory glycine receptor recently identified in the central nervous system, challen...
Aberrant neuronal excitation promotes neuroinflammation in the primary motor cortex of ischemic stroke mice
Aberrant neuronal excitation promotes neuroinflammation in the primary motor cortex of ischemic stroke mice
Current treatments for ischemic stroke aim to achieve rapid reperfusion with intravenous thrombolysis and/or endovascular ...
p-Coumaric acid alleviates neuronal damage in ischemic stroke mice by promoting BACH1 nuclear export and degradation
p-Coumaric acid alleviates neuronal damage in ischemic stroke mice by promoting BACH1 nuclear export and degradation
Oxidative damage induced by glutamate triggers neuronal death in cerebral ischemic/reperfusion injury. BTB and CNC homolog...
Transport mechanism and drug discovery of human monocarboxylate transporter 1
Transport mechanism and drug discovery of human monocarboxylate transporter 1
Human monocarboxylate transporters (MCTs) are crucial for tumour cell glycolysis. Inhibiting MCT-mediated lactate transpor...
Sustainable pH-responsive casein/hyaluronic acid layered nanoparticles for targeted delivery of metformin to colorectal cancer
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Hybrid silica materials functionalized with chloroxine-based metal complexes: Exploring synergistic antibacterial activity
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A simple reinforcement of native starch agglomerates using magnesium aluminum silicate: A study with tapioca starch and its application as a tablet diluent material
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Methotrexate-conjugated silver nanoparticles enhance chemoradiotherapy effects on U87 human glioblastoma multiforme cells: As a radiosensitizer agent to improve X-irradiation efficacy
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Photodynamic therapy Mediated by inflammatory responsive hydrogel for the treatment of infectious arthritis
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T-cell engaging bispecific outer membrane vesicles (BiTE-OMV) for targeted prostate cancer immunotherapy
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Insights on the interactions between functionalized metal-polyphenol nanocarriers and human serum albumin via spectroscopic analysis
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Modulating chemical sensitivity of triple-negative breast cancer by targeted modification of curcumin liposomes
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Development and optimization of Aloe perryi nanoemulgel loaded with cevimeline Hydrochloride‒Olive oil nanoemulsion for the treatment of complications associated with xerostomia
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Quality by design endorsed fabrication of xanthohumol loaded solid nanostructured lipid carrier based powder for effective treatment of Alzheimer's disease in rats
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Beyond erectile dysfunction: Optimization of vardenafil dihydrochloride for hepatic encephalopathy prophylaxis using hybrid lipid polymeric nanoparticles formulation
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Preparation and characterization of a modified nimodipine injection: An in vitro and in vivo study
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Flucloxacillin formulation odour acceptability: A human sensory assessment
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Novel pyranopyridine derivatives and their radiolabeled nanoconjugates: An augmented approach for targeted cancer theranostics
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Photocurable reduced graphene oxide containing vitamin E-loaded dextran based cardiac hydrogel patches: Synthesis, physical characterization and in vitro assessment
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Multifunctional tilapia skin based smart dressing of silver capped allopurinol nanoparticles for treatment of infectious burn wounds
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Cationic lipid based nanoparticles-formulated artesunate as a neurotherapeutic agent in Alzheimer's disease: Targeting inflammasome activation and pyroptosis pathway
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Deep eutectic solvent-assisted air gap electrospinning of the poly(vinyl alcohol)-tetracycline system: The influence on nanofibers alignment and antibacterial activity
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Fabrication and evaluation of self-assembled folic acid surface modified Nintedanib mixed micelles to treat Idiopathic Pulmonary Fibrosis
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Enhanced cytotoxicity of osimertinib nanocrystals against lung cancer: Preparation, characterization and cytotoxicity studies against A549 cell lines
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Central Executive Network drives delta-9-tetrahydrocannabinol (THC)-induced nonlinear changes in large-scale functional connectivity in adolescent nonhuman primates
Central Executive Network drives delta-9-tetrahydrocannabinol (THC)-induced nonlinear changes in large-scale functional connectivity in adolescent nonhuman primates
Adolescent cannabinoid exposure has been implicated in enduring modifications to adult brain circuitry; however, well-cont...
IN MEMORIAM: Floyd E. Bloom, M.D
IN MEMORIAM: Floyd E. Bloom, M.D
On January 8, 2025, the ACNP lost one of its guiding lights, Floyd E. Bloom,...
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