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Unraveling Alzheimer’s disease: insights from single-cell sequencing and spatial transcriptomic
Unraveling Alzheimer’s disease: insights from single-cell sequencing and spatial transcriptomic
1 Introduction Alzheimer’s disease (AD) is the most common form of dementia, affecting millions worldwide, with prevalen...
Trends and hotspots of stereoelectroencephalogram from 2002 to 2023: a bibliometric analysis
Introduction Stereoelectroencephalography (SEEG) is a minimally invasive diagnostic approach used in preoperative evalua...
The prevalence of obstructive sleep apnea-hypopnea syndrome in patients with multiple sclerosis: a systematic review and meta-analysis
1 Introduction The primary cause of non-traumatic neurological dysfunction in young people is multiple sclerosis (MS), a...
TP53 oncogenic variants as prognostic factors in individuals with glioblastoma: a systematic review and meta-analysis
TP53 oncogenic variants as prognostic factors in individuals with glioblastoma: a systematic review and meta-analysis
1 Introduction Glioblastoma stands as the most prevalent and aggressive primary malignant tumor of the central nervous s...
Day 3 neutrophil-to-lymphocyte ratio and its derived indices predict 90-day poor outcomes following mechanical thrombectomy in acute ischemic stroke patients
1 Introduction Acute ischemic stroke (AIS) is a leading cause of mortality and disability worldwide. According to statis...
Mental imagery for addressing mechanisms underlying motor impairments in children with attention deficit hyperactivity disorder (ADHD)
1 ADHD: definitions, etiology and diagnosis Attention deficit hyperactivity disorder (ADHD) is the most common neurodeve...
Individual metabolic brain network abnormalities associated with drug-resistant mTLE vary in surgical outcomes
1 Introduction Drug-resistant mesial temporal lobe epilepsy (DR-MTLE), a predominant form of intractable epilepsy in cli...
Changes in serum concentration of perioperative inflammatory cytokines following the timing of surgery among mild–moderate traumatic brain injury patients and factors associated
1 Introduction Traumatic brain injury (TBI) is one of the leading causes of worldwide mortality, and disability (1, 2). ...
Association between psychiatric disorders and the risk of stroke: a meta-analysis of cohort studies
Introduction By 2019, stroke remained the third leading cause of disability and the second leading cause of death global...
Establishment and evaluation of a carotid artery dissection model in rats
Introduction Cerebral artery dissection (CeAD) represents a major factor causing stroke in young and middle-aged adults....
The effectiveness of dry needling for plantar fasciitis: a systematic review and meta-analysis
1 Introduction Plantar fasciitis (PF) is the most common cause of inferior heel pain. The lifetime prevalence of PF has ...
Measuring traveling wave velocity in the basilar membrane as a potential indicator of endolymphatic hydrops in definite Ménière’s disease: a narrative review
1 Introduction Ménière’s disease (MD) is an idiopathic inner ear condition, of which the pathological feature is endolym...
Oral behaviors in Chinese temporomandibular disorder patients: insights from exploratory and confirmatory factor analyses
1 Introduction Temporomandibular disorders (TMDs) represent the second most common musculoskeletal condition, following ...
Toward the Bayesian brain: a generative model of information transmission by vestibular sensory neurons
1 Introduction Mathematical modeling of the vestibular system was pioneered by Steinhausen (1) [reviewed by Straka et al....
Clinical utility of synuclein skin biopsy in the diagnosis and evaluation of synucleinopathies
1 Introduction The diagnosis of disorders characterized as ‘synucleinopathies’ is primarily based on clinical phenomenol...
Trends in exercise therapy research for neurological diseases: a bibliometric and visualization approach from 2000 to 2024
Trends in exercise therapy research for neurological diseases: a bibliometric and visualization approach from 2000 to 2024
1 Introduction The central nervous system (CNS), consisting of the brain and spinal cord, plays a crucial role in integr...
Neuromonitoring modalities predicting neurological impairment in pediatric congenital heart disease: a systematic review
Neuromonitoring modalities predicting neurological impairment in pediatric congenital heart disease: a systematic review
1 Introduction Congenital heart disease (CHD) is the most common birth defect with a prevalence of about 8 (1–8) per 1,0...
A conception of integrated phased model combining sleep hygiene and stimulus control as an adult sleep education approach
The prevalence of mental illnesses, particularly those associated with the impact of stress, is on the rise globally. Cond...
The effect of pressing needle therapy on depression, anxiety, and sleep for patients in convalescence from COVID-19
The effect of pressing needle therapy on depression, anxiety, and sleep for patients in convalescence from COVID-19
Introduction Coronavirus disease 2019 (COVID-19) is an acute respiratory infectious disease that is characterized by occ...
Cognitive aspects of motor control deteriorate while off treatment following subthalamic nucleus deep brain stimulation surgery in Parkinson’s disease
1 Introduction Following surgery for subthalamic nucleus deep brain stimulation (STN-DBS), people with Parkinson’s disea...
The burden of epilepsy in the People’s Republic of China from 1990 to 2019: epidemiological trends and comparison with the global burden of epilepsy
The burden of epilepsy in the People’s Republic of China from 1990 to 2019: epidemiological trends and comparison with the global burden of epilepsy
BackgroundEpilepsy is associated with a significant global burden of disease, affecting over 50 million people worldwide. ...
Smartphone-based evaluation of static balance and mobility in long-lasting COVID-19 patients
Smartphone-based evaluation of static balance and mobility in long-lasting COVID-19 patients
BackgroundSARS-CoV-2 infection can lead to a variety of persistent sequelae, collectively known as long COVID-19. Deficits...
Dexmedetomidine, an alpha 2A receptor agonist, triggers seizures unilaterally in GAERS during the pre-epileptic phase: does the onset of spike-and-wave discharges occur in a focal manner?
Dexmedetomidine, an alpha 2A receptor agonist, triggers seizures unilaterally in GAERS during the pre-epileptic phase: does the onset of spike-and-wave discharges occur in a focal manner?
IntroductionThe genetic absence epilepsy rat from Strasbourg (GAERS) is a rat model for infantile absence epilepsy with sp...
Risk factors for the rupture of intracranial aneurysms: a systematic review and meta-analysis
Risk factors for the rupture of intracranial aneurysms: a systematic review and meta-analysis
PurposeThe study aimed to identify potential risk factors for aneurysm rupture by performing a systematic review and meta-...
Cohort analysis of novel SPAST variants in SPG4 patients and implementation of in vitro and in vivo studies to identify the pathogenic mechanism caused by splicing mutations
Cohort analysis of novel SPAST variants in SPG4 patients and implementation of in vitro and in vivo studies to identify the pathogenic mechanism caused by splicing mutations
IntroductionPure hereditary spastic paraplegia (SPG) type 4 (SPG4) is caused by mutations of SPAST gene. This study aimed ...
Motor fiber function in spinal muscular atrophy—analysis of conduction velocity distribution
Motor fiber function in spinal muscular atrophy—analysis of conduction velocity distribution
ObjectivesThe motor neuron survival protein, which is deficient in spinal muscular atrophy (SMA), performs numerous cellul...
High-resolution DNA methylation screening of the major histocompatibility complex in multiple sclerosis
High-resolution DNA methylation screening of the major histocompatibility complex in multiple sclerosis
BackgroundThe HLA-DRB1 gene in the major histocompatibility complex (MHC) region in chromosome 6p21 is the strongest genet...
The impact of platelet indices on ischemic stroke: a Mendelian randomization study and mediation analysis
The impact of platelet indices on ischemic stroke: a Mendelian randomization study and mediation analysis
IntroductionPlatelet indices (PIs) are hematological parameters that indicate the number, morphology, and activation of pl...
The effect of general anesthesia and conscious sedation in endovascular thrombectomy for acute ischemic stroke: an updated meta-analysis of randomized controlled trials and trial sequential analysis
The effect of general anesthesia and conscious sedation in endovascular thrombectomy for acute ischemic stroke: an updated meta-analysis of randomized controlled trials and trial sequential analysis
ObjectivesGeneral anesthesia (GA) and conscious sedation (CS) are common methods for endovascular thrombectomy (EVT) in ac...
A systematic review on functional electrical stimulation based rehabilitation systems for upper limb post-stroke recovery
A systematic review on functional electrical stimulation based rehabilitation systems for upper limb post-stroke recovery
BackgroundStroke is one of the most common neurological conditions that often leads to upper limb motor impairments, signi...
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