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Temporal and spatial expression of Phosphodiesterase-4B after sciatic nerve compression in rats and its mechanism of action on sciatic nerve repair
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Neuro-nutraceuticals: Emerging molecular and functional insights into how natural products improve brain health
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Reduction in presynaptic glutamate release and the prevention of glutamate excitotoxicity by lupeol in rats
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Dysregulation of immune system markers, gut microbiota and short-chain fatty acid production following prenatal alcohol exposure: A developmental perspective
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Kaempferol promotes angiogenesis through HIF-1α/VEGF-A/Notch1 pathway in ischemic stroke rats
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Astrocyte-Neuron Metabolic Crosstalk in Ischaemic Stroke
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DOT1L in neural development and neurological and psychotic disorders
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CB1 receptor signaling: Linking neuroplasticity, neuronal types, and mental health outcomes
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Beyond plaques and tangles: The role of immune cell dysfunction in Alzheimer's disease
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TDP-43 transports ferritin heavy chain mRNA to regulate oxidative stress in neuronal axons
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Cerebellum KCC2 protein expression plasticity in response to cerebral cortical stroke
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Sigma-1 receptor activation produces faster antidepressant-like effect through enhancement of hippocampal neuroplasticity: Focus on sigma-1-5-HT1A heteroreceptor complex
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Vagus nerve stimulation inhibits PANoptosis and promotes neurofunctional recovery of cerebral ischemic stroke in a Sirt1-dependent manner
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The novel peptide DBCH reduces LPS-stimulated NF-κB/MAPK signaling in BV-2 microglia and ameliorates cognitive impairment in scopolamine-treated mice by modulating BDNF/CREB
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An overview of mild traumatic brain injuries and emerging therapeutic targets
An overview of mild traumatic brain injuries and emerging therapeutic targets
The majority of traumatic brain injuries (TBIs), approximately 90%, are classified as mild (mTBIs). Globally, an estimated...
Research progress on mechanisms of ischemic stroke: Regulatory pathways involving Microglia
Research progress on mechanisms of ischemic stroke: Regulatory pathways involving Microglia
Ischemic stroke (IS), is caused by a transient or permanent reduction in local cerebral blood flow, leading to downstream ...
Trends and hotspots in research of traumatic brain injury from 2000 to 2022: A bibliometric study
Trends and hotspots in research of traumatic brain injury from 2000 to 2022: A bibliometric study
Traumatic brain injury (TBI) has become a major public health burden worldwide (Rubiano et al., 2015; Flanagan, 2015) and ...
PKR inhibitor protects spinal cord injury through mitigating endoplasmic reticulum stress and pyroptosis
PKR inhibitor protects spinal cord injury through mitigating endoplasmic reticulum stress and pyroptosis
Spinal cord injury (SCI) is a common neurological disorder characterized by severe inflammation as well as eternal deficit...
Inhibition of PTEN-induced kinase 1 autophosphorylation may assist in preventing epileptogenesis induced by pentylenetetrazol
Inhibition of PTEN-induced kinase 1 autophosphorylation may assist in preventing epileptogenesis induced by pentylenetetrazol
Epilepsy is a common neurological disease, characterized by repeated seizures (Lopes et al., 2015). At present, the effect...
Matrix Metalloproteinase-9 inhibitors as therapeutic drugs for traumatic brain injury
Matrix Metalloproteinase-9 inhibitors as therapeutic drugs for traumatic brain injury
Despite the advances in our knowledge of the complex pathophysiology of TBI, it remains one of the leading causes of morbi...
Interleukin-33 has the protective effect on oligodendrocytes against impairment induced by cuprizone intoxication
Interleukin-33 has the protective effect on oligodendrocytes against impairment induced by cuprizone intoxication
Oligodendrocytes (OLs) are a cell population in the central nervous system (CNS) responsible for producing myelin that wra...
Role of regulatory non-coding RNAs in traumatic brain injury
Role of regulatory non-coding RNAs in traumatic brain injury
Traumatic brain injury (TBI) is widely acknowledged as a predominant public health issue, as it has the highest incidence ...
Role of trigger receptor 2 expressed on myeloid cells in neuroinflammation－neglected multidimensional regulation of microglia
Role of trigger receptor 2 expressed on myeloid cells in neuroinflammation－neglected multidimensional regulation of microglia
Neuroinflammation is described as an inflammatory cascade in the nervous tissue that plays a pivotal role in various neuro...
P2Y12 receptor mediates apoptosis and demyelination to affect functional recovery in mice with spinal cord injury
P2Y12 receptor mediates apoptosis and demyelination to affect functional recovery in mice with spinal cord injury
Spinal cord injury (SCI) has long been regarded as a devastating condition that frequently results in motor, sensory, and ...
Projections from anteromedial thalamus nucleus to the midcingulate cortex mediate pain and anxiety-like behaviors in mice
Projections from anteromedial thalamus nucleus to the midcingulate cortex mediate pain and anxiety-like behaviors in mice
Experiencing pain or pain-related sickness can lead to an unpleasant emotional and sensory experience. Patients enduring p...
Calcium-binding protein parvalbumin in the spinal cord and dorsal root ganglia
Calcium-binding protein parvalbumin in the spinal cord and dorsal root ganglia
Ca2+ is universal secondary messenger within eukaryotic cells, triggering multiple cascades of physiological processes in ...
Mechanisms and treatments of chronic pain after traumatic brain injury
Mechanisms and treatments of chronic pain after traumatic brain injury
Traumatic brain injury (TBI) is a significant health issue that affects members of the military, Veterans, and the general...
Brain cholesterol homeostasis and its association with neurodegenerative diseases
Brain cholesterol homeostasis and its association with neurodegenerative diseases
The brain is considered to be the organ with the highest cholesterol content in the individual, despite representing a mer...
Estrogen receptor β exerts neuroprotective effects by fine-tuning mitochondrial homeostasis through NRF1/PGC-1α
Estrogen receptor β exerts neuroprotective effects by fine-tuning mitochondrial homeostasis through NRF1/PGC-1α
Alzheimer's disease (AD) is the most common form of dementia, accounting for approximately 60–80% of all dementia cases (A...
Mechanism of anti-AD action of OAB-14 by enhancing the function of glymphatic system
Mechanism of anti-AD action of OAB-14 by enhancing the function of glymphatic system
Alzheimer's disease (AD) is a prevalent chronic neurodegenerative disorder and the leading cause of dementia, characterize...
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