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Impact of Bifidobacterium longum1714® on maternal cytokine response in peripheral blood mononuclear cells
Impact of Bifidobacterium longum1714® on maternal cytokine response in peripheral blood mononuclear cells
PurposeThe maternal immune system is implicated in adverse pregnancy outcomes. Manipulation of maternal immune response by...
The causality between systemic inflammatory regulators and chronic respiratory diseases: A bidirectional Mendelian-randomization study
The causality between systemic inflammatory regulators and chronic respiratory diseases: A bidirectional Mendelian-randomization study
Chronic respiratory diseases (CRDs), featuring the constant destruction to the respiratory tract and other lung structures...
Aberrant expression of SOCS impairs the anti-leishmanial immune response
Aberrant expression of SOCS impairs the anti-leishmanial immune response
The balance between Th1- and Th2-related immune responses is a critical determinant of the outcome of Leishmania infection...
Lipopolysaccharide inhibits translation of iron chaperone PCBP1 to regulate inflammatory cytokine response in macrophage
Lipopolysaccharide inhibits translation of iron chaperone PCBP1 to regulate inflammatory cytokine response in macrophage
Macrophages are unique in controlling iron recycling and immunity. They scavenge aged and damaged red blood cells (RBCs) a...
Induction of IL-2 by interleukin-12 p40 homodimer and IL-12, but not IL-23, in microglia and macrophages: Implications for multiple sclerosis
Induction of IL-2 by interleukin-12 p40 homodimer and IL-12, but not IL-23, in microglia and macrophages: Implications for multiple sclerosis
Interleukin-2 (IL-2) is a prototypical T cell growth factor and immunoregulatory cytokine produced by T lymphocytes, dendr...
Impact of IL-6 rs1800795 and IL-17A rs2275913 gene polymorphisms on the COVID-19 prognosis and susceptibility in a sample of Iranian patients
Impact of IL-6 rs1800795 and IL-17A rs2275913 gene polymorphisms on the COVID-19 prognosis and susceptibility in a sample of Iranian patients
Since severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread, over 390 million cases have been infected world...
CXCL6 promotes the progression of NAFLD through regulation of PPARα
CXCL6 promotes the progression of NAFLD through regulation of PPARα
Nonalcoholic fatty liver disease (NAFLD), the most prevalent liver disease, is characterized by lipid deposition and steat...
Pyrogenic and inflammatory mediators are produced by polarized M1 and M2 macrophages activated with D-dimer and SARS-CoV-2 spike immune complexes
Pyrogenic and inflammatory mediators are produced by polarized M1 and M2 macrophages activated with D-dimer and SARS-CoV-2 spike immune complexes
Lung macrophages are the first line of defense against invading respiratory pathogens including SARS-CoV-2, yet activation...
NK cells and the profile of inflammatory cytokines in the peripheral blood of patients with advanced carcinomas
NK cells and the profile of inflammatory cytokines in the peripheral blood of patients with advanced carcinomas
Natural killer (NK) cells are innate lymphoid cells that play an essential role during immune responses against intracellu...
Proinflammatory pattern in the lower airways of non-asthmatic obese adolescents
Proinflammatory pattern in the lower airways of non-asthmatic obese adolescents
BackgroundObesity is known to be a pro-inflammatory condition affecting multiple organs. Obesity as a systemic pro-inflamm...
IGF2BP2 attenuates intestinal epithelial cell ferroptosis in colitis by stabilizing m6A-modified GPX4 mRNA
IGF2BP2 attenuates intestinal epithelial cell ferroptosis in colitis by stabilizing m6A-modified GPX4 mRNA
Ulcerative colitis (UC) is a chronic non-specific inflammatory bowel disease (IBD) that primarily affects the colon and re...
17-β Estradiol (E2) distinctly regulates the expression of IL-4 and IL-13 in Th2 cells via modulating the interplay between GATA3 and PU.1
17-β Estradiol (E2) distinctly regulates the expression of IL-4 and IL-13 in Th2 cells via modulating the interplay between GATA3 and PU.1
17-β Estradiol (E2), the active form of female hormone estrogen is essential for bone homeostasis, cholesterol and glucose...
Macrophages-derived exo-miR-4449 induced by Cryptococcus affects HUVEC permeability and promotes pyroptosis in BEAS-2B via the HIC1 pathway
Macrophages-derived exo-miR-4449 induced by Cryptococcus affects HUVEC permeability and promotes pyroptosis in BEAS-2B via the HIC1 pathway
Cryptococcus is widely distributed in natural environments such as soil and bird excrement, encompassing two primary serot...
Clinical utility of circulating TWEAK and CD163 as biomarkers of iron-induced cardiac decompensation in transfusion dependent thalassemia major
Clinical utility of circulating TWEAK and CD163 as biomarkers of iron-induced cardiac decompensation in transfusion dependent thalassemia major
Iron-induced cardiac decompensation (IICD) is the main cause of death in transfusion dependent thalassemia major (TDTM) pa...
Exploring the causal relationship between inflammatory cytokines and inflammatory arthritis: A Mendelian randomization study
Exploring the causal relationship between inflammatory cytokines and inflammatory arthritis: A Mendelian randomization study
ObjectivesPrevious studies have reported an association between inflammatory cytokines and inflammatory arthritis, includi...
Suppression of DNMT2/3 by proinflammatory cytokines inhibits CtBP1/2-dependent genes to promote the occurrence of atrophic nonunion
Suppression of DNMT2/3 by proinflammatory cytokines inhibits CtBP1/2-dependent genes to promote the occurrence of atrophic nonunion
Bone healing failure after a fracture often leads to nonunion, which can cause prolonged pain and disability for patients ...
Inflammatory marker levels in children with tobacco smoke exposure
Inflammatory marker levels in children with tobacco smoke exposure
Tobacco smoke exposure (TSE) in children is associated with clinical illnesses such as bronchiolitis, asthma, pneumonia, a...
Isthmin: A multifunctional secretion protein
Isthmin: A multifunctional secretion protein
Edgar identified a new secretion protein using secretion cloning to screen the secretion protein of Xenopus gastrula embry...
Allograft inflammatory factor-1 enhances inflammation and oxidative stress via the NF-κB pathway of bladder urothelium in diabetic rat model
Allograft inflammatory factor-1 enhances inflammation and oxidative stress via the NF-κB pathway of bladder urothelium in diabetic rat model
Diabetes mellitus (DM) is one of the most common chronic diseases around the world. Diabetic cystopathy (DCP), disorders a...
Even one dose of tocilizumab could hinder bad prognosis of cytokines storm in COVID-19 patients
Even one dose of tocilizumab could hinder bad prognosis of cytokines storm in COVID-19 patients
The COVID-19 pandemic has posed a major threat to public health and raised the pressure on international medical practices...
Cytokine storm in COVID-19 and malaria: Annals of pro-inflammatory cytokines
Cytokine storm in COVID-19 and malaria: Annals of pro-inflammatory cytokines
Infectious diseases are one of the major problems of the world. Despite the availability of the various high throughput sy...
The role of Interleukin-21 in autoimmune Diseases: Mechanisms, therapeutic Implications, and future directions
The role of Interleukin-21 in autoimmune Diseases: Mechanisms, therapeutic Implications, and future directions
There has been a marked increase in the prevalence and incidence of autoimmune diseases in the second half of the twentiet...
Albumin-binding recombinant human IL-18BP ameliorates macrophage activation syndrome and atopic dermatitis via direct IL-18 inactivation
Albumin-binding recombinant human IL-18BP ameliorates macrophage activation syndrome and atopic dermatitis via direct IL-18 inactivation
KeywordsIL-18 binding proteinInflammationMacrophage activating syndromeAtopic dermatitisSL335AbbreviationsAOSDadult-onset ...
Inflammation and comorbidities of chronic obstructive pulmonary disease: The cytokines put on a mask!
Inflammation and comorbidities of chronic obstructive pulmonary disease: The cytokines put on a mask!
Chronic obstructive pulmonary disease (COPD) is a common disease among elderly individuals, affecting more than 600 millio...