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Comprehensive analysis of DNA methylation gene expression profiles in GEO dataset reveals biomarkers related to malignant transformation of sinonasal inverted papilloma
Comprehensive analysis of DNA methylation gene expression profiles in GEO dataset reveals biomarkers related to malignant transformation of sinonasal inverted papilloma
DNA methylation may be involved in the regulation of malignant transformation from sinonasal inverted papilloma (SNIP) to ...
Effects of different surgical approaches on health-related quality of life in pediatric and adolescent patients with papillary thyroid carcinoma
Effects of different surgical approaches on health-related quality of life in pediatric and adolescent patients with papillary thyroid carcinoma
We aimed to compare the health-related quality of life (HRQOL) in pediatric and adolescent patients with papillary thyroid...
Comprehensive analysis of T cell exhaustion related signature for predicting prognosis and immunotherapy response in HNSCC
Comprehensive analysis of T cell exhaustion related signature for predicting prognosis and immunotherapy response in HNSCC
T cell exhaustion (TEX) signifies a condition of T cell disorder which implicate the therapeutic benefits and prognostic s...
The prognostic value of LAYN in HPV-related head and neck squamous cell carcinoma and its influence on immune cell infiltration
The prognostic value of LAYN in HPV-related head and neck squamous cell carcinoma and its influence on immune cell infiltration
HPV-positive head and neck squamous cell carcinoma (HNSCC) exhibits different characteristics from HPV-negative tumors in ...
The prevalence of ADSL (rs3788579) and CYP1A2 (rs17861162) polymorphisms in female breast cancer patients in North-West Iran
The prevalence of ADSL (rs3788579) and CYP1A2 (rs17861162) polymorphisms in female breast cancer patients in North-West Iran
Breast cancer is a prevalent and significant contributor to cancer-related mortality among women worldwide. Its increasing...
Causal relationship between gut microbiota and prostate cancer contributes to the gut-prostate axis: insights from a Mendelian randomization study
Causal relationship between gut microbiota and prostate cancer contributes to the gut-prostate axis: insights from a Mendelian randomization study
Changes in gut microbiota abundance have been linked to prostate cancer development. However, the causality of the gut-pro...
Low serum total cholesterol levels predict inferior prognosis of patients with POEMS syndrome
Low serum total cholesterol levels predict inferior prognosis of patients with POEMS syndrome
Low serum cholesterol levels are associated with increased tumor morbidity and mortality. However, the relationship betwee...
Identification and validation of a novel six-gene signature based on mucinous adenocarcinoma-related gene molecular typing in colorectal cancer
Identification and validation of a novel six-gene signature based on mucinous adenocarcinoma-related gene molecular typing in colorectal cancer
Colorectal mucinous adenocarcinoma (MAC) is a particular pathological type that has yet to be thoroughly studied. This stu...
Unveiling NUSAP1 as a common gene signature linking chronic HBV infection and HBV-related HCC
Unveiling NUSAP1 as a common gene signature linking chronic HBV infection and HBV-related HCC
Hepatitis B virus (HBV) is a significant contributor to the development of hepatocellular carcinoma (HCC). Chronic HBV inf...
The impact of radiomics in the management of soft tissue sarcoma
The impact of radiomics in the management of soft tissue sarcoma
Soft tissue sarcomas (STSs) are rare malignancies. Pre-therapeutic tumour grading and assessment are crucial in making tre...
SAA1 regulated by S1P/S1PR1 promotes the progression of ESCC via β-catenin activation
SAA1 regulated by S1P/S1PR1 promotes the progression of ESCC via β-catenin activation
Serum amyloid A1 (SAA1), an inflammation-related molecule, is associated with the malignant progression of many tumors. Th...
Clinical experience of consolidative radiotherapy for localized metastatic non-small cell lung cancer who showed favorable tumor response after systemic treatment
Clinical experience of consolidative radiotherapy for localized metastatic non-small cell lung cancer who showed favorable tumor response after systemic treatment
Our study has aimed to assess the effects of consolidative high-dose radiotherapy on clinical outcomes in patients with lo...
Identification of gene variation feature for targeted therapy of non-small cell lung cancer through combined method of DNA and RNA sequencing
Identification of gene variation feature for targeted therapy of non-small cell lung cancer through combined method of DNA and RNA sequencing
Next generation sequencing (NGS) is typically used to reveal tumor gene variation feature for targeted therapy of various ...
LncRNA XIST promotes bladder cancer progression by modulating miR-129-5p/TNFSF10 axis
LncRNA XIST promotes bladder cancer progression by modulating miR-129-5p/TNFSF10 axis
The differential expression, biological function, and ceRNA regulatory mechanism of lncRNA XIST in bladder cancer (BC) wer...
Transcriptome and single-cell transcriptomics reveal prognostic value and potential mechanism of anoikis in skin cutaneous melanoma
Transcriptome and single-cell transcriptomics reveal prognostic value and potential mechanism of anoikis in skin cutaneous melanoma
Skin cutaneous melanoma (SKCM) is a highly lethal cancer, ranking among the top four deadliest cancers. This underscores t...
Transarterial chemoembolization with/without immune checkpoint inhibitors plus tyrosine kinase inhibitors for unresectable hepatocellular carcinoma: a single center, propensity score matching real-world study
Transarterial chemoembolization with/without immune checkpoint inhibitors plus tyrosine kinase inhibitors for unresectable hepatocellular carcinoma: a single center, propensity score matching real-world study
To explore the efficacy and safety of Transarterial chemoembolization (TACE) in combination with immune checkpoint inhibit...
DDOST is associated with tumor immunosuppressive microenvironment in cervical cancer
DDOST is associated with tumor immunosuppressive microenvironment in cervical cancer
Evidence has revealed that DDOST plays an important role in cancer development and progression. However, there are no repo...
GABPB1 plays a cancer-promoting role in non-small cell lung cancer
GABPB1 plays a cancer-promoting role in non-small cell lung cancer
GABPB1, the gene that encodes two isoforms of the beta subunit of GABP, has been identified as an oncogene in multiple mal...
A programmed cell death-related gene signature to predict prognosis and therapeutic responses in liver hepatocellular carcinoma
A programmed cell death-related gene signature to predict prognosis and therapeutic responses in liver hepatocellular carcinoma
Programmed cell death (PCD) functions critically in cancers and PCD-related genes are associated with tumor microenvironme...
Resection margins, lymph node harvest and 3 year survival in open and laparoscopic colorectal cancer surgery; a prospective cohort study
Resection margins, lymph node harvest and 3 year survival in open and laparoscopic colorectal cancer surgery; a prospective cohort study
Laparoscopic colorectal cancer surgery has been gaining popularity in the last decade. However, there are concerns about a...
The adverse outcome pathway for breast cancer: a knowledge management framework bridging biomedicine and toxicology
The adverse outcome pathway for breast cancer: a knowledge management framework bridging biomedicine and toxicology
Breast cancer is the most common cancer worldwide, with an estimated 2.3 million new cases diagnosed every year. Effective...
β-Arrestin2 promotes docetaxel resistance of castration-resistant prostate cancer via promoting hnRNP A1-mediated PKM2 alternative splicing
β-Arrestin2 promotes docetaxel resistance of castration-resistant prostate cancer via promoting hnRNP A1-mediated PKM2 alternative splicing
To investigate the influence of β-arrestin2 on the docetaxel resistance in castration-resistant prostate cancer (CRPC...
ALOX5AP is a new prognostic indicator in acute myeloid leukemia
ALOX5AP is a new prognostic indicator in acute myeloid leukemia
The overexpression of ALOX5AP has been observed in many types of cancer and has been identified as an oncogene. However, i...
Mapping the immunological battlefield in gastric cancer: prognostic implications of an immune gene expression signature
Mapping the immunological battlefield in gastric cancer: prognostic implications of an immune gene expression signature
Gastric cancer (GC) is a heterogeneous malignancy with variable clinical outcomes. The immune system has been implicated i...
ARAP1 negatively regulates stress fibers formation and metastasis in lung adenocarcinoma via controlling Rho signaling
ARAP1 negatively regulates stress fibers formation and metastasis in lung adenocarcinoma via controlling Rho signaling
Small GTPases regulate multiple important cellular behaviors and their activities are strictly controlled by a mass of reg...
A comprehensive analysis of SLC25A1 expression and its oncogenic role in pan-cancer
A comprehensive analysis of SLC25A1 expression and its oncogenic role in pan-cancer
The solute carrier family 25 member 1 (SLC25A1) is currently the only known human transporter for citrat...
Exosomal miR-200c and miR-141 as cerebrospinal fluid biopsy biomarkers for the response to chemotherapy in primary central nervous system lymphoma
Exosomal miR-200c and miR-141 as cerebrospinal fluid biopsy biomarkers for the response to chemotherapy in primary central nervous system lymphoma
To improve early diagnosis and chemotherapy efficacy monitoring in primary central nervous system lymphoma (PCNSL), cerebr...
A risk score model based on lipid metabolism-related genes could predict response to immunotherapy and prognosis of lung adenocarcinoma: a multi-dataset study and cytological validation
A risk score model based on lipid metabolism-related genes could predict response to immunotherapy and prognosis of lung adenocarcinoma: a multi-dataset study and cytological validation
Lipid metabolism is a key factor in tumorigenesis and drug resistance, and models related to lipid metabolism have shown p...
Integrated analysis of single-cell and bulk RNA-sequencing reveals the poor prognostic value of ABCA1 in gastric adenocarcinoma
Integrated analysis of single-cell and bulk RNA-sequencing reveals the poor prognostic value of ABCA1 in gastric adenocarcinoma
ATP-binding cassette A1 (ABCA1) is a potential prognostic marker for various tumor types. However, the biological effects ...
Machine learning-based predictive model for the differential diagnosis of ≤ 5 cm gastric stromal tumor and gastric schwannoma based on CT images
Machine learning-based predictive model for the differential diagnosis of ≤ 5 cm gastric stromal tumor and gastric schwannoma based on CT images
The clinical symptoms of ≤ 5 cm gastric stromal tumor (GST) and gastric schwannoma (GS) are sim...
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