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RFX2 promotes tumor cell stemness through epigenetic regulation of PAF1 in spinal ependymoma
RFX2 promotes tumor cell stemness through epigenetic regulation of PAF1 in spinal ependymoma
Spinal ependymoma (SE) is a rare tumor that is most commonly low-grade and tends to recur when complete tumor resection is...
Focused ultrasound combined with radiotherapy for malignant brain tumor: a preclinical and clinical study
Focused ultrasound combined with radiotherapy for malignant brain tumor: a preclinical and clinical study
Blood–brain barrier (BBB) remains to be the major obstacle to conquer in treating patients with malignant brain tumo...
Ganciclovir as a potential treatment for glioma: a systematic review and meta-analysis
Ganciclovir as a potential treatment for glioma: a systematic review and meta-analysis
Glioma is a challenging malignant tumor with a low survival rate and no effective treatment. Recently, ganciclovir, an ant...
Management strategies for intracranial progression in ALK-positive non-small cell lung cancer: a real-world cohort study
Management strategies for intracranial progression in ALK-positive non-small cell lung cancer: a real-world cohort study
ALK-positive NSCLC patients exhibit a particularly high propensity for the development of brain metastases. Current guidel...
Incidental meningiomas: a current and increasingly common challenge
Incidental meningiomas: a current and increasingly common challenge
Näslund O, Strand PS, Solheim O et al (2023) Incidence, management, and outcome of incidental meningioma: what has happene...
Treatment of very elderly glioblastoma patients ≥ 75 years of age: whom to treat
Treatment of very elderly glioblastoma patients ≥ 75 years of age: whom to treat
The prognosis of patients ≥ 75 years suffering from glioblastoma is poor. Novel therapies are usually re...
Pyruvate kinase M2 (PKM-2) expression and prognostic significance in glioblastoma patients
Pyruvate kinase M2 (PKM-2) expression and prognostic significance in glioblastoma patients
Pyruvate kinase M2 (PKM2) is a key enzyme that catalyzes the irreversible and final step of glycolysis. It is closely asso...
A multi-site phase I trial of Veliparib with standard radiation and temozolomide in patients with newly diagnosed glioblastoma multiforme (GBM)
A multi-site phase I trial of Veliparib with standard radiation and temozolomide in patients with newly diagnosed glioblastoma multiforme (GBM)
A multi-site Phase I trial was conducted to determine the safety, maximum tolerated dose, and pharmacokinetics (PK) of Vel...
Development of a “Geo-Tagged” tumor sample registry: intra-operative linkage of sample location to imaging
Development of a “Geo-Tagged” tumor sample registry: intra-operative linkage of sample location to imaging
There is a growing body of literature documenting glioma heterogeneity in terms of radiographic, histologic, molecular, an...
Liquid biopsy in the setting of leptomeningeal metastases: a systematic review and meta-analysis
Liquid biopsy in the setting of leptomeningeal metastases: a systematic review and meta-analysis
The blood-brain barrier can prevent circulating tumor DNA (ctDNA) derived from the central nervous system from entering th...
Targeted immunotherapy for glioblastoma involving whole tumor-derived autologous cells in the upfront setting after craniotomy
Targeted immunotherapy for glioblastoma involving whole tumor-derived autologous cells in the upfront setting after craniotomy
To date, immunotherapeutic approaches in glioblastoma (GBM) have had limited clinical efficacy as compared to other solid ...
Treatment and survival of patients with small cell lung cancer and brain metastasis
Treatment and survival of patients with small cell lung cancer and brain metastasis
To elucidate treatment patterns and their outcomes in patients with small cell lung cancer (SCLC) and brain metastasis (BM...
Effects of intrathecal pemetrexed on the survival of patients with leptomeningeal metastasis from lung adenocarcinoma: a propensity score matching analysis
Effects of intrathecal pemetrexed on the survival of patients with leptomeningeal metastasis from lung adenocarcinoma: a propensity score matching analysis
To explore the impact of intrathecal pemetrexed (IP) on the survival of lung adenocarcinoma (LUAC) patients with leptomeni...
Generation of patient-derived pediatric pilocytic astrocytoma in-vitro models using SV40 large T: evaluation of a modeling workflow
Generation of patient-derived pediatric pilocytic astrocytoma in-vitro models using SV40 large T: evaluation of a modeling workflow
Although pediatric low-grade gliomas (pLGG) are the most common pediatric brain tumors, patient-derived cell lines reflect...
Capturing evolving definitions of 12 select rare CNS tumors: a timely report from CBTRUS and NCI-CONNECT
Capturing evolving definitions of 12 select rare CNS tumors: a timely report from CBTRUS and NCI-CONNECT
Incidence, prevalence, and survival are population-based statistics describing cancer burden. The National Cancer Institut...
The ruse of reduction – comment to Zeng et al.
The ruse of reduction – comment to Zeng et al.
Share this articleAnyone you share the following link with will be able to read this content:Get shareable linkSorry, a sh...
The long non-coding RNA OTX2-AS1 promotes tumor growth and predicts response to BCL-2 inhibition in medulloblastoma
The long non-coding RNA OTX2-AS1 promotes tumor growth and predicts response to BCL-2 inhibition in medulloblastoma
Primary brain tumors are a leading cause of cancer-related death in children, and medulloblastoma is the most common malig...
Stereotactic radiosurgery for large vestibular schwannomas: 2.5 cm and beyond
Stereotactic radiosurgery for large vestibular schwannomas: 2.5 cm and beyond
Pikis S, Mantziaris G, Kormath Anand R, Nabeel AM, Sheehan D, Sheehan K, Reda WA, Tawadros SR, Abdelkarim K, El-Shehaby AM...
Particle beam radiotherapy in the treatment of WHO grade 2 and 3 meningiomas: an early experience from Shanghai Proton and Heavy Ion Center
Particle beam radiotherapy in the treatment of WHO grade 2 and 3 meningiomas: an early experience from Shanghai Proton and Heavy Ion Center
To investigate the efficacy and safety of particle beam radiotherapy (PBRT) in the management of patients with WHO grade 2...
Expertise in neuro-oncology: 10,000 h/10 years and opportunities for flattening the curve
Expertise in neuro-oncology: 10,000 h/10 years and opportunities for flattening the curve
Competing interests The authors declare no competing intere...
Focused ultrasound for brain metastases: an update on global clinical trials
Focused ultrasound for brain metastases: an update on global clinical trials
Despite advances in immunotherapy and targeted treatments for malignancies of the central nervous system (CNS), the treatm...
Predictors for delayed awakening in adult glioma patients receiving awake craniotomy under monitored anesthesia care
Predictors for delayed awakening in adult glioma patients receiving awake craniotomy under monitored anesthesia care
Delayed awakening after anesthetic discontinuation during awake craniotomy is associated with somnolence during functional...
Qualitative MR features to identify non-enhancing tumors within glioblastoma’s T2-FLAIR hyperintense lesions
Qualitative MR features to identify non-enhancing tumors within glioblastoma’s T2-FLAIR hyperintense lesions
To identify qualitative MRI features of non-(contrast)-enhancing tumor (nCET) in glioblastoma’s T2-FLAIR hyperintens...
Correction to: Undetected pseudoprogressions in the CeTeG/NOA-09 trial: hints from postprogression survival and MRI analyses
Correction to: Undetected pseudoprogressions in the CeTeG/NOA-09 trial: hints from postprogression survival and MRI analyses
Thomas Zeyen and Daniel Paech have contributed equally.Division of Clinical Neurooncology, Department of Neurology, Univer...
Enhanced sensitivity of electrocorticography during awake craniotomy using a novel circular grid electrode
Enhanced sensitivity of electrocorticography during awake craniotomy using a novel circular grid electrode
Awake craniotomy with intraoperative functional brain mapping (FBM) bedside neurological testing is an important technique...
Correction to: Impact of boost sequence in concurrent chemo-radiotherapy on newly diagnosed IDH-wildtype glioblastoma multiforme
Correction to: Impact of boost sequence in concurrent chemo-radiotherapy on newly diagnosed IDH-wildtype glioblastoma multiforme
Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam...
Incidence, management, and outcome of incidental meningioma: what has happened in 10 years?
Incidence, management, and outcome of incidental meningioma: what has happened in 10 years?
The aim of this study was to study the use of brain scanning, and the subsequent findings of presumed incidental meningiom...
Clinical outcomes of stereotactic biopsy on children with pontine diffuse midline glioma
Clinical outcomes of stereotactic biopsy on children with pontine diffuse midline glioma
Diffuse midline glioma (DMG) of the pons occurs in pediatric patients and carries a dismal prognosis. Biopsy is not necess...
Safety of microneurosurgical interventions for superficial and deep-seated brain metastases: single-center cohort study of 637 consecutive cases
Safety of microneurosurgical interventions for superficial and deep-seated brain metastases: single-center cohort study of 637 consecutive cases
Microneurosurgical techniques have greatly improved over the past years due to the introduction of new technology and surg...
Postoperative stereotactic radiosurgery for intracranial solitary fibrous tumors: systematic review and pooled quantitative analysis
Postoperative stereotactic radiosurgery for intracranial solitary fibrous tumors: systematic review and pooled quantitative analysis
Intracranial solitary fibrous tumors (SFTs), formerly hemangiopericytomas (HPCs), are rare, aggressive dural-based mesench...
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