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Antibody-Drug Conjugates in Breast Cancer: The Road Towards Biologically-Informed Selection and Sequencing
Antibody-Drug Conjugates in Breast Cancer: The Road Towards Biologically-Informed Selection and Sequencing
In this review, we discuss evidence supporting the use of antibody-drug conjugates (ADCs) in breast cancer treatment, desc...
Cardiotoxic Effects Following CAR-T Cell Therapy: A Literature Review
Cardiotoxic Effects Following CAR-T Cell Therapy: A Literature Review
This paper reviewed the current literature on incidence, clinical manifestations, and risk factors of Chimeric Antigen Rec...
Advances in Radiation Oncology in Soft Tissue Sarcoma
Advances in Radiation Oncology in Soft Tissue Sarcoma
To review recent advances with radiation therapy (RT) for soft tissue sarcomas (STS). Newer data showcases hypofractionate...
Novel Surgical Initiatives in Gastroenteropancreatic Neuroendocrine Tumours
Novel Surgical Initiatives in Gastroenteropancreatic Neuroendocrine Tumours
Neuroendocrine tumours (NET) are rare entities arising from hormone producing cells in the gastroentero-pancreatic (GEP) t...
Effectiveness of Pelvic Floor Muscle and Education-based Therapies on Bladder, Bowel, Vaginal, Sexual, Psychological Function, Quality of Life, and Pelvic Floor Muscle Function in Females Treated for Breast Cancer: A Systematic Review
Effectiveness of Pelvic Floor Muscle and Education-based Therapies on Bladder, Bowel, Vaginal, Sexual, Psychological Function, Quality of Life, and Pelvic Floor Muscle Function in Females Treated for Breast Cancer: A Systematic Review
Breast malignancy is the most common cancer in females. Symptoms of pelvic floor disorders and sexual dysfunction secondar...
Weight Management for Fertility-Preservation Therapy in Endometrial Cancer: Opportunities and Challenges
Weight Management for Fertility-Preservation Therapy in Endometrial Cancer: Opportunities and Challenges
Obesity is increasingly recognized as a significant factor impacting the outcomes of fertility-preserving therapies for en...
Paediatric Renal Tumors: A State-of-the-Art Review
Paediatric Renal Tumors: A State-of-the-Art Review
Pediatric renal tumors comprise a wide range of conditions, both malignant and benign, that affect children and require a ...
Cell-free Tumor DNA: a Promising Technology for Diagnosis, Surveillance and Therapeutic Decision in Urothelial Carcinoma of the Bladder
Cell-free Tumor DNA: a Promising Technology for Diagnosis, Surveillance and Therapeutic Decision in Urothelial Carcinoma of the Bladder
This narrative review aims to discuss the latest evidence for cell-free tumor DNA (ctDNA) use in bladder cancer, future pe...
Current State of Evidence on Definitions and Management of High-Risk Multiple Myeloma
Current State of Evidence on Definitions and Management of High-Risk Multiple Myeloma
This review aims to address the subgroup of patients with newly diagnosed multiple myeloma (NDMM) who have high-risk multi...
Epidemiology of cancer in older adults: a systematic review of age-related differences in solid malignancies treatment
Epidemiology of cancer in older adults: a systematic review of age-related differences in solid malignancies treatment
We examined the latest epidemiological research on age-related differences in cancer treatment and selected outcomes, amon...
Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
This review aims to outline the current understanding of the molecular drivers and treatment paradigms of gastrointestinal...
Defining The Role for Hormone Therapy in Biochemically Recurrent Prostate Cancer: What Counts as a Win for Patients?
Defining The Role for Hormone Therapy in Biochemically Recurrent Prostate Cancer: What Counts as a Win for Patients?
We evaluate unique clinical and drug development challenges in biochemically recurrent (BCR) prostate cancer. We examine r...
ChatGPT in Oncology Diagnosis and Treatment: Applications, Legal and Ethical Challenges
ChatGPT in Oncology Diagnosis and Treatment: Applications, Legal and Ethical Challenges
This study aims to systematically review the trajectory of artificial intelligence (AI) development in the medical field, ...
Beneath the Surface: The Emerging Role of Ultra-Processed Foods in Obesity-Related Cancer
Beneath the Surface: The Emerging Role of Ultra-Processed Foods in Obesity-Related Cancer
Ultra-processed foods (UPFs) are becoming more and more important in daily diets around the world; in some cases, they can...
Emerging Therapeutic Targets of Neuroendocrine Prostate Cancer
Emerging Therapeutic Targets of Neuroendocrine Prostate Cancer
Treatment-emergent neuroendocrine prostate cancer (NEPC) is aggressive and lethal. As androgen receptor signaling inhibito...
Correction to: Postmastectomy Functional Impairments
Correction to: Postmastectomy Functional Impairments
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Integrative Approaches in the Treatment of Patients Affected by Lymphoma
Integrative Approaches in the Treatment of Patients Affected by Lymphoma
Lymphoma is the most frequent hematological malignancy with wide disease spectrum of watchful waiting period, active treat...
Shifting Strategies in the Treatment of Pediatric Craniopharyngioma
Shifting Strategies in the Treatment of Pediatric Craniopharyngioma
Craniopharyngiomas represent one of the most challenging diseases to treat. Despite their benign histology, and after many...
Genomic Landscape of Pleural Mesothelioma and Therapeutic Aftermaths
Genomic Landscape of Pleural Mesothelioma and Therapeutic Aftermaths
In this article, we provide a comprehensive analysis of recent progress in the genetic characterisation of pleural mesothe...
Limb Amputations in Cancer: Modern Perspectives, Outcomes, and Alternatives
Limb Amputations in Cancer: Modern Perspectives, Outcomes, and Alternatives
This review summarizes current findings regarding limb amputation within the context of cancer, especially in osteosarcoma...
Postmastectomy Functional Impairments
Postmastectomy Functional Impairments
This narrative review aims to offer a thorough summary of functional impairments commonly encountered by breast cancer sur...
Immune Priming with Spatially Fractionated Radiation Therapy
Immune Priming with Spatially Fractionated Radiation Therapy
This review aims to summarize the current preclinical and clinical evidence of nontargeted immune effects of spatially fra...
Advances in Treatment of Waldenström Macroglobulinemia
Advances in Treatment of Waldenström Macroglobulinemia
The discovery of recurring somatic mutations, in particular MYD88 and CXCR4 mutations, in Waldenström macroglobulinem...
What Is New in Cutaneous T Cell Lymphoma?
What Is New in Cutaneous T Cell Lymphoma?
This review focuses on updates in prognosis, pathogenesis, and treatment of cutaneous T cell lymphoma (CTCL). Cohort studi...
Prostate Cancer in Transgender Women: Epidemiology, Clinical Characteristics, and Management Challenges
Prostate Cancer in Transgender Women: Epidemiology, Clinical Characteristics, and Management Challenges
To systematically review the evidence on prostate cancer (PCa) in transgender women (TGW). A total of 25 studies were incl...
Navigating the Rapidly Evolving Advanced Urothelial Carcinoma Treatment Landscape: Insights from Italian Experts
Navigating the Rapidly Evolving Advanced Urothelial Carcinoma Treatment Landscape: Insights from Italian Experts
To discuss recent advances in the treatment of advanced urothelial carcinoma (UC) and how best to incorporate new therapie...
Evolving Role of CAR T Cell Therapy in First- and Second-Line Treatment of Large B Cell Lymphoma
Evolving Role of CAR T Cell Therapy in First- and Second-Line Treatment of Large B Cell Lymphoma
We review the recent practice-changing trials of anti-CD19 chimeric antigen receptor (CAR) T cell therapies in large B cel...
Advances in the Management of Recurrent Cervical Cancer: State of the Art and Future Perspectives
Advances in the Management of Recurrent Cervical Cancer: State of the Art and Future Perspectives
This review aims to give an insight into the currently available options for recurrent/metastatic (R/M) cervical cancer (C...
Towards Improving the Efficacy of PSMA-Targeting Radionuclide Therapy for Late-Stage Prostate Cancer—Combination Strategies
Towards Improving the Efficacy of PSMA-Targeting Radionuclide Therapy for Late-Stage Prostate Cancer—Combination Strategies
[177Lu]Lu-PSMA-617 is a radiopharmaceutical that emits beta-minus radiation and targets prostate-specific membrane antigen...
Novel Therapeutic Options for Small Cell Lung Cancer
Novel Therapeutic Options for Small Cell Lung Cancer
The aim of this review is to focus on the recent advances in the molecular knowledge of small cell lung cancer (SCLC) and ...
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