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Prostate ductal adenocarcinoma with MLH1 copy number loss, microsatellite instability high and BRCA2 mutation
Prostate ductal adenocarcinoma with MLH1 copy number loss, microsatellite instability high and BRCA2 mutation
Mismatch repair deficiency (MMRd) or microsatellite instability high (MSI-H) is rare in prostate cancer and more frequentl...
Prophylactic use of duloxetine hydrochloride in oxaliplatin-induced first-bite syndrome
Prophylactic use of duloxetine hydrochloride in oxaliplatin-induced first-bite syndrome
First-bite syndrome (FBS) is manifested as acute and severe pain in the parotid region occurring at the first bite of a me...
Successful immunotherapy with ipilimumab and nivolumab in a patient with pulmonary sclerosing pneumocytoma
Successful immunotherapy with ipilimumab and nivolumab in a patient with pulmonary sclerosing pneumocytoma
Pulmonary sclerosing pneumocytoma (PSP) is a rare form of lung cancer that occasionally presents with lymph node and extra...
Successful osimertinib treatment for Meckel’s cave metastasis: a case report
Successful osimertinib treatment for Meckel’s cave metastasis: a case report
Osimertinib has emerged as the standard first-line treatment for advanced non-small cell lung cancer (NSCLC) with EGFR mut...
Reduction of bleeding by cabozantinib in metastatic renal cell carcinoma with hereditary hemorrhagic telangiectasia
Reduction of bleeding by cabozantinib in metastatic renal cell carcinoma with hereditary hemorrhagic telangiectasia
Hereditary hemorrhagic telangiectasia (HHT) is a rare genetic disorder characterized by refractory recurrent epistaxis and...
Colorectal anastomotic leakage after conversion surgery for advanced endometrial cancer treated with lenvatinib plus pembrolizumab: a case report
Colorectal anastomotic leakage after conversion surgery for advanced endometrial cancer treated with lenvatinib plus pembrolizumab: a case report
The combination therapy of lenvatinib plus pembrolizumab (LP) is increasingly recognized as an important second-line regim...
Resistant PRL-secreting PitNET associated with breast carcinoma: a case report and literature review
Resistant PRL-secreting PitNET associated with breast carcinoma: a case report and literature review
In several studies, hyperprolactinemia has been associated with increased breast cancer risk. Evidence shows that prolacti...
Squamous cell carcinoma in a long-standing suprapubic cystostomy: a urological oddball
Squamous cell carcinoma in a long-standing suprapubic cystostomy: a urological oddball
Squamous cell carcinoma (SCC) rarely accounts for 2–5% of urinary bladder cancer. Chronic irritation of the bladder ...
Long-term conservative treatment of chylous ascites in gynecological malignant surgery: a case report and literature review
Long-term conservative treatment of chylous ascites in gynecological malignant surgery: a case report and literature review
Chylous ascites is a rare complication of abdominal surgery. Although most patients show improvement with conservative tre...
Thoracoscopic right apical segmentectomy in a patient with tracheal bronchus: a case report and review of literature
Thoracoscopic right apical segmentectomy in a patient with tracheal bronchus: a case report and review of literature
A 70-year-old female patient was referred to our department for further abnormal chest shadow assessment in the right uppe...
Chronic progressive pulmonary aspergillosis within the irradiated field after stereotactic body radiotherapy: two case reports
Chronic progressive pulmonary aspergillosis within the irradiated field after stereotactic body radiotherapy: two case reports
Stereotactic body radiation therapy (SBRT) is the standard treatment for patients who are medically inoperable or who refu...
A case of remarkable response to combined radiation therapy, enfortumab vedotin, and pembrolizumab in metastatic urothelial carcinoma
A case of remarkable response to combined radiation therapy, enfortumab vedotin, and pembrolizumab in metastatic urothelial carcinoma
Enfortumab Vedotin (EV), an antibody–drug conjugate targeting Nectin-4, combined with pembrolizumab (Pem), has becom...
Cisplatin-induced therapy-related myelodysplastic syndrome during avelumab maintenance therapy for metastatic urothelial carcinoma
Cisplatin-induced therapy-related myelodysplastic syndrome during avelumab maintenance therapy for metastatic urothelial carcinoma
A 64 year-old man underwent a radical cystectomy for muscle-invasive bladder cancer. Five years later, lung and m...
Gastrectomy after neoadjuvant chemotherapy in five cases of locally advanced gastric cancer with pancreatic head invasion
Gastrectomy after neoadjuvant chemotherapy in five cases of locally advanced gastric cancer with pancreatic head invasion
Locally advanced gastric cancer (LAGC) with pancreatic head invasion (T4b) carries a poor prognosis despite radical surger...
Laparoscopically resected appendiceal dual tumor composed of goblet cell carcinoma and low-grade mucinous neoplasm: a case report and literature review
Laparoscopically resected appendiceal dual tumor composed of goblet cell carcinoma and low-grade mucinous neoplasm: a case report and literature review
Dual tumors, comprising two different types of tumor, are uncommon pathologic findings. Appendiceal goblet cell carcinoid ...
Exceptional response to brigatinib following alectinib failure in a patient with ALK fusion-positive duodenal carcinoma
Exceptional response to brigatinib following alectinib failure in a patient with ALK fusion-positive duodenal carcinoma
Patients with advanced duodenal carcinoma typically have a poor prognosis due to limited practical chemotherapy options. W...
Coexistence of plasmablastic lymphoma and adenocarcinoma in the stomach: a case report and literature review
Coexistence of plasmablastic lymphoma and adenocarcinoma in the stomach: a case report and literature review
Plasmablastic lymphoma (PBL) is a rare B-cell lymphoma. Reports on primary gastric PBL are limited, and its endoscopic fea...
Maintenance avelumab therapy for urothelial carcinoma in a hemodialysis patient: a case report
Maintenance avelumab therapy for urothelial carcinoma in a hemodialysis patient: a case report
In recent years, immune checkpoint inhibitors have attracted attention in treatment for urothelial carcinoma. However, man...
Potential drug interactions between pazopanib and proton pump inhibitors/potassium-competitive acid blockers in patients with soft tissue sarcoma
Potential drug interactions between pazopanib and proton pump inhibitors/potassium-competitive acid blockers in patients with soft tissue sarcoma
Because absorption of the oral drug pazopanib depends on gastric pH, concomitant use of proton pump inhibitors (PPIs)/pota...
Endometrioid adenocarcinoma arising from inguinal endometriosis during follow-up for gastric cancer surgery: a case report and literature review
Endometrioid adenocarcinoma arising from inguinal endometriosis during follow-up for gastric cancer surgery: a case report and literature review
Malignant transformation of inguinal endometriosis is rare. A 56-year-old woman underwent surgery for advanced gastric can...
Ureteral obstruction following transurethral resection of bladder cancer within the Hutch’s diverticulum
Ureteral obstruction following transurethral resection of bladder cancer within the Hutch’s diverticulum
Here, we report a rare case of bladder cancer within the left congenital periureteral diverticulum, termed the Hutch’...
A case of massive hemoptysis caused by lung cancer saved by V-V ECMO and hemostasis achieved by radiotherapy
A case of massive hemoptysis caused by lung cancer saved by V-V ECMO and hemostasis achieved by radiotherapy
Massive hemoptysis is one of the fatal complications of lung cancer. There is no established standard treatment method for...
Bilateral adrenal metastases from renal cell carcinoma after robot-assisted partial nephrectomy
Bilateral adrenal metastases from renal cell carcinoma after robot-assisted partial nephrectomy
Renal cell carcinoma often metastasizes to the adrenals; however, bilateral adrenal metastases are rare. We here report a ...
S-1 as an alternative treatment after 5-fluorouracil-induced coronary vasospasm in a patient with small bowel adenocarcinoma: a case report
S-1 as an alternative treatment after 5-fluorouracil-induced coronary vasospasm in a patient with small bowel adenocarcinoma: a case report
5-Fluorouracil (5-FU) is a chemotherapeutic agent used worldwide to treat various solid tumors. It may cause adverse cardi...
Relapsing cytokine release syndrome in a patient with metastatic renal cell carcinoma treated with pembrolizumab and axitinib therapy
Relapsing cytokine release syndrome in a patient with metastatic renal cell carcinoma treated with pembrolizumab and axitinib therapy
As immune checkpoint inhibitors become more widely available, the optimal management of immune-related adverse events (irA...
A case of difficult-to-diagnose hepatic reactive lymphoid hyperplasia finally diagnosed by using PCR analysis of IgH-gene rearrangements: a case report
A case of difficult-to-diagnose hepatic reactive lymphoid hyperplasia finally diagnosed by using PCR analysis of IgH-gene rearrangements: a case report
Reactive lymphoid hyperplasia (RLH) of the liver is extremely rare. Despite advancements in diagnostic imaging technology,...
Two cases of dermatomyositis associated with neuroendocrine tumors
Two cases of dermatomyositis associated with neuroendocrine tumors
Dermatomyositis is an idiopathic inflammatory myopathy with cutaneous manifestations, which is associated with several typ...
Tumor lysis syndrome followed by tumor regression after COVID-19 in a patient with chronic lymphocytic leukemia
Tumor lysis syndrome followed by tumor regression after COVID-19 in a patient with chronic lymphocytic leukemia
Coronavirus disease 2019 (COVID-19) can become lethal in patients with hematological malignancies; however, several cases ...
Sarcomatoid renal cell carcinoma with an inferior vena cava tumor thrombus that was completely resected by robot-assisted laparoscopic radical nephrectomy after neoadjuvant therapy nivolumab plus ipilimumab: a case report
Sarcomatoid renal cell carcinoma with an inferior vena cava tumor thrombus that was completely resected by robot-assisted laparoscopic radical nephrectomy after neoadjuvant therapy nivolumab plus ipilimumab: a case report
We here present a patient with a sarcomatoid renal cell carcinoma complicated by inferior vena cava tumor thrombus that we...
Conversion surgery after successful response to chemotherapy (S-1 + oxaliplatin + nivolumab) in a patient with stage IV gastric cancer with peritoneal metastasis (P1, CY1): a case report
Conversion surgery after successful response to chemotherapy (S-1 + oxaliplatin + nivolumab) in a patient with stage IV gastric cancer with peritoneal metastasis (P1, CY1): a case report
We here present a case report of a patient with Stage IV gastric cancer with peritoneal metastasis (P1, CY1) who underwent...
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