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Endocrine-disrupting chemical, methylparaben, in environmentally relevant exposure promotes hazardous effects on the hypothalamus-pituitary-thyroid axis
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A Guide to Pathophysiology, Signaling Pathways, and Preclinical Models of Liver Fibrosis
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EDNRB negatively regulates glycolysis to exhibit anti-tumor functions in prostate cancer by cGMP/PKG pathway
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Transcriptomic Analysis of Effects of Developmental PCB Exposure in the Hypothalamus of Female Rats
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Salvia hispanica L. (chia) seed have beneficial effects upon visceral adipose tissues extracellular matrix disorders and inflammation developed in a sucrose-rich diet-induced adiposity rodent model
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Genetic loss of Uchl1 leads to female infertility by affecting oocyte quality and follicular development
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Melatonin induces white-to-beige adipocyte transdifferentiation through melatonin receptor 1-mediated direct browning and indirect M2 polarization
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Liraglutide promotes osteogenic differentiation of mesenchymal stem cells by inhibiting M1 macrophage polarization and CXCL9 release in vitro
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Simultaneous treatment with palm-LEAP2(1–14) and feeding high-fat diet attenuates liver lipid metabolism but not obesity: Sign of selective resistance to palm-LEAP2(1–14)
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Nicotine increases hepatocyte transthyretin turnover: A possible mechanism for the protective effect of smoking on preeclampsia?
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NAT10 drives endometriosis progression through acetylation and stabilization of TGFB1 mRNA
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Characterization of thyroid hormone transport in a human choroid plexus papilloma cell line (HIBCPP) as an in vitro blood-cerebrospinal fluid barrier model
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MDPAO1 peptide from human milk enhances brown adipose tissue thermogenesis and mitigates obesity
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FDA-approved polypeptide PTH 1–34 impedes palmitic acid-mediated osteoblasts dysfunction by promoting its differentiation and thereby improving skeletal health
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Corrigendum to “PTH-dependent stabilization of RANKL mRNA is associated with increased phosphorylation of the KH-type splicing regulatory protein” [Molecul. Cellul. Endocrinol. 595 (2025) 112412]
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Housing temperature influences metabolic phenotype of heart failure with preserved ejection fraction in J vs N strain C57BL/6 mice
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Functional analysis of SRY variants in individuals with 46,XY differences of sex development
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USP7 promotes decidualization of ESCs by STAT3/PR axis during early pregnancy
USP7 promotes decidualization of ESCs by STAT3/PR axis during early pregnancy
A prospective human pregnancy requires successful implantation and decidualization, which are two critically orchestrated ...
Nrf2 inhibition regulates intracellular lipid accumulation in mouse insulinoma cells and improves insulin secretory function
Nrf2 inhibition regulates intracellular lipid accumulation in mouse insulinoma cells and improves insulin secretory function
Obesity and overweight can raise the risk of type 2 diabetes (T2D). A high amount of fat in the pancreas, known as intrapa...
Temperature- and genotype-dependent stress response and activation of the hypothalamus-pituitary-interrenal axis during temperature-induced sex reversal in pejerrey Odontesthes bonariensis, a species with genotypic and environmental sex determination
Temperature- and genotype-dependent stress response and activation of the hypothalamus-pituitary-interrenal axis during temperature-induced sex reversal in pejerrey Odontesthes bonariensis, a species with genotypic and environmental sex determination
In fish, genetic and environmental factors may interact to determine gonadal fate (Hattori et al., 2020). Genetic factors ...
Endosomal signaling via cAMP in parathyroid hormone (PTH) type 1 receptor biology
Endosomal signaling via cAMP in parathyroid hormone (PTH) type 1 receptor biology
Available online 20 November 2023, 112107Author links open overlay panel, , AbstractCompartmentalization of GPCR signaling...
A MUFA/carotenoid-rich oil ameliorated insulin resistance by improving inflammation and oxidative stress in obese rats
A MUFA/carotenoid-rich oil ameliorated insulin resistance by improving inflammation and oxidative stress in obese rats
Obesity is characterized by excessive fat accumulation in adipose tissue, and its origin is multifactorial. The excessive ...
The BRAFV600E mutation maintains the aggressiveness of papillary thyroid cancers requiring downregulation of primary cilia
The BRAFV600E mutation maintains the aggressiveness of papillary thyroid cancers requiring downregulation of primary cilia
Papillary thyroid cancers (PTCs) account for more than 80% of all thyroid cancers (TCs). PTC generally has an indolent nat...
17β-Estradiol inhibits hydrogen peroxide-induced senescence and apoptosis in human umbilical vein endothelial cells by regulating the THBS1/TGF-β/Smad axis
17β-Estradiol inhibits hydrogen peroxide-induced senescence and apoptosis in human umbilical vein endothelial cells by regulating the THBS1/TGF-β/Smad axis
Cardiovascular diseases (CVDs), including a series of high age-associated disorders, such as atherosclerosis, hypertension...
Novel regulatory roles of small G protein GDP dissociation stimulator (smgGDS) in insulin secretion from pancreatic β-cells
Novel regulatory roles of small G protein GDP dissociation stimulator (smgGDS) in insulin secretion from pancreatic β-cells
It is well established that GSIS from pancreatic β-cells requires the generation of soluble second messengers including cy...
Downregulation of homeobox A1 in human granulosa cells is involved in diminished ovarian reserve through promoting cell apoptosis and mitochondrial dysfunction
Downregulation of homeobox A1 in human granulosa cells is involved in diminished ovarian reserve through promoting cell apoptosis and mitochondrial dysfunction
Diminished ovarian reserve (DOR) is a reproductive endocrine disease that causes impaired female fertility due to a reduct...
Male-specific vasotocin expression in the medaka tuberal hypothalamus: Androgen dependence and probable role in aggression
Male-specific vasotocin expression in the medaka tuberal hypothalamus: Androgen dependence and probable role in aggression
Aggression is an adaptive behavioral trait that is crucial for competition for territories, food, and mating partners and ...
Comparison of INSM1 immunostaining with established neuroendocrine markers synaptophysin and chromogranin A in over 14,000 neuroendocrine and non-neuroendocrine tumors
Comparison of INSM1 immunostaining with established neuroendocrine markers synaptophysin and chromogranin A in over 14,000 neuroendocrine and non-neuroendocrine tumors
Author links open overlay panelKatharina Möller a, Ria Uhlig a, Natalia Gorbokon a, David Dum a, Anne Menz a, Franziska Bü...
Activation of mitophagy improves cognitive dysfunction in diabetic mice with recurrent non-severe hypoglycemia
Activation of mitophagy improves cognitive dysfunction in diabetic mice with recurrent non-severe hypoglycemia
Maintaining blood sugar level is critical for the management of patients with diabetes. However, accidental recurrent exce...
Deregulation of ABCG1 early in life contributes to prostate carcinogenesis in maternally malnourished offspring rats
Deregulation of ABCG1 early in life contributes to prostate carcinogenesis in maternally malnourished offspring rats
Over the past decades, the incidence of non-communicable chronic diseases (NCDs), such as cardiovascular diseases, respira...
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