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Long non-coding RNA ENSMUST00000197208 promotes a shift in the Th17/Treg ratio via the P2X7R-NLRP3 inflammasome axis in collagen-induced arthritis
Long non-coding RNA ENSMUST00000197208 promotes a shift in the Th17/Treg ratio via the P2X7R-NLRP3 inflammasome axis in collagen-induced arthritis
Recently, long non‑coding RNAs (lncRNAs) have been implicated in several human diseases, including arthritis. Howeve...
A ubiquitin–proteasome system-related signature to predict prognosis, immune infiltration, and therapy efficacy for breast cancer
A ubiquitin–proteasome system-related signature to predict prognosis, immune infiltration, and therapy efficacy for breast cancer
The ubiquitin–proteasome system (UPS) is an essential regulatory system for maintaining homeostasis, and its dysfunc...
Immune cells and hypertension
Immune cells and hypertension
Hypertension is one of the leading causes of death due to target organ injury from cardiovascular disease. Although there ...
Correction: Major histocompatibility complex class I molecule expression by pancreatic cancer cells is regulated by activation and inhibition of the epidermal growth factor receptor
Correction: Major histocompatibility complex class I molecule expression by pancreatic cancer cells is regulated by activation and inhibition of the epidermal growth factor receptor
Cite this articleKnoche, S.M., Larson, A.C., Brumfield, G.L. et al. Correction: Major histocompatibility complex class I m...
Fructus lycii oligosaccharide alleviates acute liver injury via PI3K/Akt/mTOR pathway
Fructus lycii oligosaccharide alleviates acute liver injury via PI3K/Akt/mTOR pathway
Regulating the immune-environment is essential for treating acute liver injury (ALI). However, the deficiency of an effect...
Comparative analyses of various IgE-mediated and non-IgE-mediated inducers of mast cell degranulation for in vitro study
Comparative analyses of various IgE-mediated and non-IgE-mediated inducers of mast cell degranulation for in vitro study
In vitro investigations of mast cell (MC) degranulation are essential for studying many diseases, particularly allergy and...
Impact of microparticles released during murine systemic inflammation on macrophage activity and reactive nitrogen species regulation
Impact of microparticles released during murine systemic inflammation on macrophage activity and reactive nitrogen species regulation
Microparticles (MPs) packaged with numerous bioactive molecules are essential vehicles in cellular communication in variou...
Insights into the immunological description of cryoglobulins with regard to detection and characterization in Slovenian rheumatological patients
Insights into the immunological description of cryoglobulins with regard to detection and characterization in Slovenian rheumatological patients
The detection of cryoglobulins (CG) used to diagnose cryoglobulinemic vasculitis requires strict adherence to protocol, wi...
Semaphorin 3 a restores the ability of type 1 regulatory T cells to suppress food allergy
Semaphorin 3 a restores the ability of type 1 regulatory T cells to suppress food allergy
Food allergy (FA) is a common immune disorder that involves dysfunctional immune regulation. More remedies for restoring i...
Prevalence and sociodemographic correlates of antinuclear antibody testing by indirect immunofluorescence or solid-phase assays in a Spanish population: the Camargo Cohort
Prevalence and sociodemographic correlates of antinuclear antibody testing by indirect immunofluorescence or solid-phase assays in a Spanish population: the Camargo Cohort
Autoantibodies are the hallmark of autoimmunity, and specifically, antinuclear antibodies (ANA) are one of the most releva...
Association of IL-23R and IL-10 variations with Behçet disease: a genetic analysis study
Association of IL-23R and IL-10 variations with Behçet disease: a genetic analysis study
Behçet disease (BD) is an autoimmune and autoinflammatory disease mainly affecting the Silk Road countries. The inter...
Role of LINC00240 on T-helper 9 differentiation in allergic rhinitis through influencing DNMT1-dependent methylation of PU.1
Role of LINC00240 on T-helper 9 differentiation in allergic rhinitis through influencing DNMT1-dependent methylation of PU.1
Allergic rhinitis (AR) is a common allergic disease with increasing prevalence globally. However, the molecular mechanism ...
Increased synthesis and intestinal expression of IL-39 in patients with inflammatory bowel disease
Increased synthesis and intestinal expression of IL-39 in patients with inflammatory bowel disease
IL-39 (Interleukin-39) is a heterodimeric cytokine composed of IL-23p19 and EBI3 (Epstein-Barr virus-induced gene 3) subun...
Rational design of multi-epitope-based vaccine by exploring all dengue virus serotypes proteome: an immunoinformatic approach
Rational design of multi-epitope-based vaccine by exploring all dengue virus serotypes proteome: an immunoinformatic approach
Millions of people’s lives are being devastated by dengue virus (DENV), a severe tropical and subtropical illness sp...
Differential expression of TOB/BTG family members in patients with plaque psoriasis: cross-sectional study
Differential expression of TOB/BTG family members in patients with plaque psoriasis: cross-sectional study
TOB/BTG is a family of antiproliferative proteins that play an important role in the regulation of immune responses, actin...
Association study between killer immunoglobulin-like receptor polymorphisms and susceptibility to COVID-19 disease: a systematic review and meta-analysis
Association study between killer immunoglobulin-like receptor polymorphisms and susceptibility to COVID-19 disease: a systematic review and meta-analysis
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a known virus that leads to a respiratory disease called c...
Palpitation in women with silicone breast implants: association with autoantibodies against autonomic nervous system
Palpitation in women with silicone breast implants: association with autoantibodies against autonomic nervous system
We explored a possible association between palpitation manifestation in women with silicone breast implants (SBIs) with ci...
Current genetic defects in common variable immunodeficiency patients on the geography between Europe and Asia: a single-center experience
Current genetic defects in common variable immunodeficiency patients on the geography between Europe and Asia: a single-center experience
Identification of the causes of monogenetic common variable immunodeficiency (CVID) patients has rapidly increased in the ...
Harmonization of ANA testing challenge: quantification strategy to accurately predict end-point titers avoiding serial dilution
Harmonization of ANA testing challenge: quantification strategy to accurately predict end-point titers avoiding serial dilution
Despite the advantages of automated systems for antinuclear antibody (ANA) analysis, the prediction of end-point titers av...
Total serum IgA levels and HLA-DQB1*02:01 allelic status
Total serum IgA levels and HLA-DQB1*02:01 allelic status
Immunoglobulin A Deficiency (IgAD) is the most common primary immunodeficiency and is significantly associated wi...
Diverse functions of myeloid-derived suppressor cells in autoimmune diseases
Diverse functions of myeloid-derived suppressor cells in autoimmune diseases
Since myeloid-derived suppressor cells (MDSCs) were found suppressing immune responses in cancer and other pathological co...
MiR-7 deficiency promotes Th1 polarization of CD4+T cells and enhances the antitumor effect in adoptive cell therapy for lung cancer
MiR-7 deficiency promotes Th1 polarization of CD4+T cells and enhances the antitumor effect in adoptive cell therapy for lung cancer
Adoptive-cell-therapy (ACT) is important therapeutic approach against cancer. We previously showed that miR-7 deficiency e...
Elevated neutrophil-lymphocyte ratio is associated with high rates of ICU mortality, length of stay, and invasive mechanical ventilation in critically ill patients with COVID-19
Elevated neutrophil-lymphocyte ratio is associated with high rates of ICU mortality, length of stay, and invasive mechanical ventilation in critically ill patients with COVID-19
Neutrophil and lymphocyte ratio (NLR) has emerged as a complementary marker in intensive care. This study aimed to associa...
Nanotechnology-based theranostic and prophylactic approaches against SARS-CoV-2
Nanotechnology-based theranostic and prophylactic approaches against SARS-CoV-2
SARS-CoV-2 (COVID-19) pandemic has been an unpredicted burden on global healthcare system by infecting over 700 million in...
ANCA detection with solid phase chemiluminescence assay: diagnostic and severity association in vasculitis
ANCA detection with solid phase chemiluminescence assay: diagnostic and severity association in vasculitis
ANCA-associated vasculitis (AAV) comprises a group of necrotizing vasculitis that mainly affects small- and medium-sized v...
MICA and NLRP3 gene polymorphisms interact synergistically affecting the risk of ankylosing spondylitis
MICA and NLRP3 gene polymorphisms interact synergistically affecting the risk of ankylosing spondylitis
Ankylosing spondylitis (AS) is an autoinflammatory disease that affects the sacroiliac joints, causing stiffness and pain ...
How the immune response to the structural proteins of SARS-CoV-2 affects the retinal vascular endothelial cells: an immune thrombotic and/or endotheliopathy process with in silico modeling
How the immune response to the structural proteins of SARS-CoV-2 affects the retinal vascular endothelial cells: an immune thrombotic and/or endotheliopathy process with in silico modeling
Thrombotic events associated with SARS-CoV-2 at the vascular endothelium still remains unclear. The aim of the current stu...
A high affinity and specificity anti-HER2 single-domain antibody (VHH) that targets trastuzumab’s epitope with versatile biochemical, biological, and medical applications
A high affinity and specificity anti-HER2 single-domain antibody (VHH) that targets trastuzumab’s epitope with versatile biochemical, biological, and medical applications
In the past decade, various single-domain antibodies from llamas, also known as VHH or nanobody, have been discovered with...
Dominance and improved survivability of human γδT17 cell subset aggravates the immunopathogenesis of pemphigus vulgaris
Dominance and improved survivability of human γδT17 cell subset aggravates the immunopathogenesis of pemphigus vulgaris
Human γδ T cells are highly enriched in epithelial cell-dominated compartments like skin. Nonetheless, their fun...
Integrating core subtractive proteomics and reverse vaccinology for multi-epitope vaccine design against Rickettsia prowazekii endemic typhus
Integrating core subtractive proteomics and reverse vaccinology for multi-epitope vaccine design against Rickettsia prowazekii endemic typhus
Rickettsia prowazekii is an intracellular, obligate, gram-negative coccobacillus responsible for epidemic typhus. Usually,...
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