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Janus kinase inhibition prevents autoimmune diabetes in LEW.1WR1 rats
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LAMP3-mediated epithelial-mesenchymal transition promotes the invasion and excessive proliferation of fibroblast-like synoviocytes in rheumatoid arthritis
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Histological pattern of non-infectious thoracic aortitis impacts mortality
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CAR-T cell targeting three receptors on autoreactive B cells for systemic lupus erythematosus therapy
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Associations between domestic hard water exposure and incident psoriasis in adults: Insights from the UK Biobank cohort study
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Pulmonary and serum cytokine profiles of patients with anti-ARS and anti-MDA5 antibodies
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Primary Cesarean delivery and future risk of maternal autoimmune disease: A population-based cohort study
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Identification of clonally expanded T-cell receptor sequences in giant cell arteritis
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Familial patterns of alopecia areata: A systematic review and meta-analysis
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Anti-retinal immune response in sarcoid uveitis: A potential role for PCLO as an antigenic target
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Diversity and function of regulatory T cells in health and autoimmune diseases
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Glycobiology of psoriasis: A review
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The impact of gut microbiome on immune and metabolic homeostasis in type 1 diabetes: Clinical insights for prevention and treatment strategies
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Immunobiology of bile and cholangiocytes
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Selective disruption of Traf1/cIAP2 interaction attenuates inflammatory responses and rheumatoid arthritis
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Treg fitness signatures as a biomarker for disease activity in Juvenile Idiopathic Arthritis
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Loss of function of XBP1 splicing activity of IRE1α favors B cell tolerance breakdown
Loss of function of XBP1 splicing activity of IRE1α favors B cell tolerance breakdown
Autoimmune diseases affect around 10 % of the world population, and are characterized by a complex etiology, combining gen...
Associations between CD70 methylation of T cell DNA and age in adults with systemic lupus erythematosus and population controls: The Michigan Lupus Epidemiology & Surveillance (MILES) Program
Associations between CD70 methylation of T cell DNA and age in adults with systemic lupus erythematosus and population controls: The Michigan Lupus Epidemiology & Surveillance (MILES) Program
Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease for which specific etiologic agents remain largely u...
High-resolution HLA genotyping in inclusion body myositis refines 8.1 ancestral haplotype association to DRB1*03:01:01 and highlights pathogenic role of arginine-74 of DRβ1 chain
High-resolution HLA genotyping in inclusion body myositis refines 8.1 ancestral haplotype association to DRB1*03:01:01 and highlights pathogenic role of arginine-74 of DRβ1 chain
ObjectivesInclusion body myositis (IBM) is a progressive inflammatory-degenerative muscle disease of older individuals, wi...
Neointimal myofibroblasts contribute to maintaining Th1/Tc1 and Th17/Tc17 inflammation in giant cell arteritis
Neointimal myofibroblasts contribute to maintaining Th1/Tc1 and Th17/Tc17 inflammation in giant cell arteritis
Vascular smooth muscle cells (VSMCs) have been shown to play a role in the pathogenesis of giant cell arteritis (GCA) thro...
AIM/CD5L ameliorates autoimmune arthritis by promoting removal of inflammatory DAMPs at the lesions
AIM/CD5L ameliorates autoimmune arthritis by promoting removal of inflammatory DAMPs at the lesions
Volume 142, January 2024, 103149Author links open overlay panel, , , , , , , , , , , Highlights•Autoimmune arthritis is re...
2023 International Consensus Guidance for the use of Tripterygium Wilfordii Hook F in the treatment of active rheumatoid arthritis
2023 International Consensus Guidance for the use of Tripterygium Wilfordii Hook F in the treatment of active rheumatoid arthritis
BackgroundRheumatoid arthritis (RA) is a chronic autoimmune disorder that affects the joints and produces pain, swelling, ...
Lung transplantation in pulmonary sarcoidosis
Lung transplantation in pulmonary sarcoidosis
Sarcoidosis is a multisystem inflammatory disease characterized by noncaseating granulomas of unknown etiology [1,2]. Up t...
Targeting NF-κB signaling in B cells as a potential new treatment modality for ANCA-associated vasculitis
Targeting NF-κB signaling in B cells as a potential new treatment modality for ANCA-associated vasculitis
B lineage cells are critically involved in ANCA-associated vasculitis (AAV), evidenced by alterations in circulating B cel...
Novel biomarker discovery through comprehensive proteomic analysis of lupus mouse serum
Novel biomarker discovery through comprehensive proteomic analysis of lupus mouse serum
Systemic lupus erythematosus (SLE; lupus) primarily affects women of reproductive age [1]. Unpredictable flares of inflamm...
Integrative single-cell analysis reveals distinct adaptive immune signatures in the cutaneous lesions of pemphigus
Integrative single-cell analysis reveals distinct adaptive immune signatures in the cutaneous lesions of pemphigus
Pemphigus is an organ-specific autoimmune bullous disease characterized by the presence of IgG autoantibodies (autoAbs) ta...
Single-cell transcriptomic profiling reveals a pathogenic role of cytotoxic CD4+ T cells in giant cell arteritis
Single-cell transcriptomic profiling reveals a pathogenic role of cytotoxic CD4+ T cells in giant cell arteritis
Giant cell arteritis (GCA) is a systemic vasculitis mediated by an aberrant immunological response against the blood vesse...
Novel and unique rheumatoid factors cross-react with viral epitopes in COVID-19
Novel and unique rheumatoid factors cross-react with viral epitopes in COVID-19
Rheumatoid factors (RFs) are antibodies of any isotype that bind the Fc region of IgG. Initially discovered in 1939 [1], R...
K2P2.1 is a regulator of inflammatory cell responses in idiopathic inflammatory myopathies
K2P2.1 is a regulator of inflammatory cell responses in idiopathic inflammatory myopathies
K2P2.1 (TREK1), a two-pore domain potassium channel, has emerged as regulator of leukocyte transmigration into the central...
Pathogenicity of functionally activated PD-1+CD8+ cells and counterattacks by muscular PD-L1 through IFNγ in myositis
Pathogenicity of functionally activated PD-1+CD8+ cells and counterattacks by muscular PD-L1 through IFNγ in myositis
Polymyositis (PM) and dermatomyositis (DM), subsets of idiopathic inflammatory myopathies (IIMs), are chronic autoimmune d...
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