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Evaluation of the Safety of Rapid Administration of Undiluted High-Dose Intravenous Levetiracetam
Evaluation of the Safety of Rapid Administration of Undiluted High-Dose Intravenous Levetiracetam
BackgroundIntravenous (IV) levetiracetam (LEV) is an antiseizure medication traditionally given as an intermittent infusio...
Guillain-Barré Syndrome with Rapid Onset and Autonomic Dysfunction Following First Dose of Pfizer-BioNTech COVID-19 Vaccine: A Case Report
Guillain-Barré Syndrome with Rapid Onset and Autonomic Dysfunction Following First Dose of Pfizer-BioNTech COVID-19 Vaccine: A Case Report
Guillain-Barre syndrome (GBS) is an immune-mediated, often post-infectious illness manifesting as an acute, characteristic...
Seizures and Headaches in a 34-Year-Old Woman With Systemic Lupus Erythematosus
Seizures and Headaches in a 34-Year-Old Woman With Systemic Lupus Erythematosus
1. Parente, L . Deflazacort: therapeutic index, relative potency and equivalent doses versus other corticosteroids. BMC Ph...
Unilateral Terson Syndrome Following Distal Middle Cerebral Artery Aneurysm Rupture
Unilateral Terson Syndrome Following Distal Middle Cerebral Artery Aneurysm Rupture
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Anti-NMDAr Encephalitis and COVID-19 in a Patient With Systemic pANCA-Vasculitis and Recurrent Varicella Zoster Infection
Anti-NMDAr Encephalitis and COVID-19 in a Patient With Systemic pANCA-Vasculitis and Recurrent Varicella Zoster Infection
IntroductionThere is a complex interplay between systemic autoimmunity, immunosuppression, and infections. Any or all of t...
COVID-19–Associated Acute Asymmetric Hemorrhagic Necrotizing Encephalopathy: A Case Report
COVID-19–Associated Acute Asymmetric Hemorrhagic Necrotizing Encephalopathy: A Case Report
Background: Coronavirus disease 2019 (COVID-19) has been associated with many neurological complications affecting the cen...
Clinical Problem Solving: Decreased Level of Consciousness and Unexplained Hydrocephalus
Clinical Problem Solving: Decreased Level of Consciousness and Unexplained Hydrocephalus
We present a clinical reasoning case of 42-year-old male with a history of type 1 diabetes who presented to hospital with ...
Return to Work Within Four Months of Grade 3 Diffuse Axonal Injury
Return to Work Within Four Months of Grade 3 Diffuse Axonal Injury
Neuroprognostication following diffuse axonal injury (DAI) has historically relied on neuroimaging techniques with lower s...
5-Fluorouracil Neurotoxicity in the Absence of Dihydropyrimidine Dehydrogenase Deficiency Case Report
5-Fluorouracil Neurotoxicity in the Absence of Dihydropyrimidine Dehydrogenase Deficiency Case Report
5 fluorouracil (5-FU)-related neurotoxicity is a rare and severe complication of 5-FU administration. Dihydropyrimidine de...
Acute Cerebellitis and Myeloradiculitis Associated With SARS-CoV-2 Infection in Common Variable Immunodeficiency—A Case Report
Acute Cerebellitis and Myeloradiculitis Associated With SARS-CoV-2 Infection in Common Variable Immunodeficiency—A Case Report
The role of the adaptive immune system in mediating COVID-19 is largely unknown. Therefore, it is difficult to predict the...
Delayed Thrombus on Carotid Web: Case Report With Escalation of Treatment
Delayed Thrombus on Carotid Web: Case Report With Escalation of Treatment
Carotid artery web is an underrecognized source and is found in about 1-2% of patients with acute ischemic stroke. Althoug...
Cerebral Venous Sinus Thrombosis due to Thrombosis with Thrombocytopenia Syndrome Following Ad26.COV2.S: A First Real-World Case Report of a Male Subject
Cerebral Venous Sinus Thrombosis due to Thrombosis with Thrombocytopenia Syndrome Following Ad26.COV2.S: A First Real-World Case Report of a Male Subject
Thrombosis with Thrombocytopenia Syndrome (TTS) or Vaccine-induced Immune Thrombotic Thrombocytopenia (VITT) had been repo...
Foix-Chavany-Marie Syndrome as Result of Acute Bilateral Frontal-Opercular Strokes
Foix-Chavany-Marie Syndrome as Result of Acute Bilateral Frontal-Opercular Strokes
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Fixed, Dilated, and Conversing—Unreactive Pupil With Preserved Consciousness Indicating Acutely Rising Intracranial Pressure due to Traumatic Intraparenchymal Contusions: Case Report and Review of the Literature
Fixed, Dilated, and Conversing—Unreactive Pupil With Preserved Consciousness Indicating Acutely Rising Intracranial Pressure due to Traumatic Intraparenchymal Contusions: Case Report and Review of the Literature
Patients with fixed and dilated pupils (FDPs) due to rising intracranial pressure (ICP) typically experience a deteriorati...
Paroxysmal Hypothermia With Prominent Parkinsonian Features After Suprachiasmatic Tumor Resection
Paroxysmal Hypothermia With Prominent Parkinsonian Features After Suprachiasmatic Tumor Resection
Paroxysmal hypothermia (PH) is a rare syndrome of stereotyped episodes of hypothermia, bradycardia, and altered mental sta...
Extensive Cerebral Arteriovenous Malformation-Associated Intraventricular Hemorrhage
Extensive Cerebral Arteriovenous Malformation-Associated Intraventricular Hemorrhage
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Difficulties Detecting Clinically Relevant Factor Xa Inhibitor Levels Prior to Reversal With Andexanet Alfa for Intracranial Hemorrhage
Difficulties Detecting Clinically Relevant Factor Xa Inhibitor Levels Prior to Reversal With Andexanet Alfa for Intracranial Hemorrhage
Coagulation factor Xa (recombinant), inactivated-zhzo (andexanet alfa) is approved for reversal of life-threatening bleedi...
Primary Sjögren’s Syndrome Presenting as Recurrent Ischemic Strokes
Primary Sjögren’s Syndrome Presenting as Recurrent Ischemic Strokes
Primary Sjogren’s Syndrome (PSS) is an autoimmune exocrinopathy, with protean manifestations affecting multiple organ syst...
Isolated High-Grade Malignancy of the Spinal Cord Presenting as Longitudinally Extensive Transverse Myelitis
Isolated High-Grade Malignancy of the Spinal Cord Presenting as Longitudinally Extensive Transverse Myelitis
This article characterizes 2 cases of longitudinally extensive transverse myelitis (LETM) that did not respond to immunoth...
Spinomedullary Weston Hurst Syndrome After COVID-19 and Influenza Co-Infection: A Case Report
Spinomedullary Weston Hurst Syndrome After COVID-19 and Influenza Co-Infection: A Case Report
The neurological complications of coronavirus disease 2019 (SARS-CoV-2, COVID-19) have so far included a range of para- an...
Herpes Zoster Ophthalmicus Causing Delayed Optic Perineuritis
Herpes Zoster Ophthalmicus Causing Delayed Optic Perineuritis
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Response to Letter to the Editor: Confounding and Misclassification Obscures the Association Between Spinal Manipulation and Spontaneous Intracranial Hypotension
Response to Letter to the Editor: Confounding and Misclassification Obscures the Association Between Spinal Manipulation and Spontaneous Intracranial Hypotension
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Stroke Incidence and Outcome in a Population With COVID-19
Stroke Incidence and Outcome in a Population With COVID-19
Background and Purpose:COVID-19 is associated with systemic thromboembolism including stroke. The study evaluated the 30-d...
Secondary Hemophagocytic Lymphohistiocytosis Causing Hemorrhagic Encephalomyelitis and Spinal Subarachnoid Hemorrhage: A Case Report
Secondary Hemophagocytic Lymphohistiocytosis Causing Hemorrhagic Encephalomyelitis and Spinal Subarachnoid Hemorrhage: A Case Report
We are writing to present an interesting and novel case from our practice of a patient who presented with altered mental s...
Letter to the Editor: Confounding and Misclassification Obscures the Association Between Spinal Manipulation and Spontaneous Intracranial Hypotension
Letter to the Editor: Confounding and Misclassification Obscures the Association Between Spinal Manipulation and Spontaneous Intracranial Hypotension
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Letter to the Editor: Methodological Limitations and Selection Bias Undermine Certainty of Findings Relating Chiropractic to Spontaneous Intracranial Hypotension
Letter to the Editor: Methodological Limitations and Selection Bias Undermine Certainty of Findings Relating Chiropractic to Spontaneous Intracranial Hypotension
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Delayed-Onset Heparin-Induced Thrombocytopenia With Cerebral Venous Sinus Thrombosis Following Total Knee Arthroplasty: Case Report
Delayed-Onset Heparin-Induced Thrombocytopenia With Cerebral Venous Sinus Thrombosis Following Total Knee Arthroplasty: Case Report
Heparin-induced thrombocytopenia (HIT) is a prothrombotic state caused by autoantibodies against platelet factor 4 (PF4)-h...
Delays in Diagnosis and Treatment of Bacterial Meningitis in NYC: Retrospective Cohort Analysis
Delays in Diagnosis and Treatment of Bacterial Meningitis in NYC: Retrospective Cohort Analysis
Community-acquired bacterial meningitis (CABM) morbidity and mortality remains high in those infected. Rapid diagnosis and...
Neurological Considerations for the Care of Patients With Severe Obesity
Neurological Considerations for the Care of Patients With Severe Obesity
Patients with severe obesity tend to have higher rates of morbidities which can complicate and even lengthen their hospita...
Transcirculation Embolization to New Territory During Mechanical Thrombectomy for Acute Ischemic Stroke
Transcirculation Embolization to New Territory During Mechanical Thrombectomy for Acute Ischemic Stroke
Embolization in new territories (ENT) is a known complication of mechanical thrombectomy with incidence dependent upon a v...
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