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Efficacy and Safety of Ciprofol Versus Propofol as Anesthetic for Patients Undergoing Painless Colonoscopy
Efficacy and Safety of Ciprofol Versus Propofol as Anesthetic for Patients Undergoing Painless Colonoscopy
Ciprofol is a novel propofol analogue with a characteristic of hemodynamic stability. At present, there is a lack of resea...
Safety of Co-Crystal of Tramadol-Celecoxib (CTC) in Patients with Acute Moderate-to-Severe Pain: Pooled Analysis of Three Phase 3 Randomized Trials
Safety of Co-Crystal of Tramadol-Celecoxib (CTC) in Patients with Acute Moderate-to-Severe Pain: Pooled Analysis of Three Phase 3 Randomized Trials
Multi-modal analgesia is desirable for the management of acute pain since it can provide effective pain relief at lower do...
Comparison of Oliceridine to Remifentanil for Optimal Analgesia in Mechanical Ventilation (CO-ROAM): Study Protocol for a Multicenter Randomized Controlled Trial
Comparison of Oliceridine to Remifentanil for Optimal Analgesia in Mechanical Ventilation (CO-ROAM): Study Protocol for a Multicenter Randomized Controlled Trial
Critically ill patients often endure pain, a distressing experience that can trigger diverse pathophysiological consequenc...
Patients’ Experiences During the Long Journey Before Initiating Migraine Prevention with a Calcitonin Gene-Related Peptide (CGRP) Monoclonal Antibody (mAb)
Patients’ Experiences During the Long Journey Before Initiating Migraine Prevention with a Calcitonin Gene-Related Peptide (CGRP) Monoclonal Antibody (mAb)
Migraine is under-diagnosed and under-treated. Many people with migraine do not seek medical care, and those who do may in...
Clinical Efficacy of Auricular Vagus Nerve Stimulation in the Treatment of Chronic and Acute Pain: A Systematic Review and Meta-analysis
Clinical Efficacy of Auricular Vagus Nerve Stimulation in the Treatment of Chronic and Acute Pain: A Systematic Review and Meta-analysis
Current guidelines for pain treatment recommend a personalized, multimodal and interdisciplinary approach as well as the u...
An Additive Effect of Instrument-Assisted Soft Tissue Mobilization with Spinal Manipulation in Cervicogenic Headache: a Randomized Controlled Trial
An Additive Effect of Instrument-Assisted Soft Tissue Mobilization with Spinal Manipulation in Cervicogenic Headache: a Randomized Controlled Trial
There is a multitude of evidence supporting the use of manual and manipulative therapy techniques for patients with cervic...
Lumbar Sympathetic Block to Treat CRPS in an 18-Month-Old Girl: A Breaking Barriers Case Report and Review of Literature
Lumbar Sympathetic Block to Treat CRPS in an 18-Month-Old Girl: A Breaking Barriers Case Report and Review of Literature
Children under the age of 3 years have been diagnosed with complex regional pain syndrome (CRPS). They were found to be fu...
Preoperative Analgesia Efficacy of Liposomal Bupivacaine Following Pericapsular Nerve Group (PENG) Block in Patients with Hip Fracture: A Randomized Controlled Observer-Blinded Study
Preoperative Analgesia Efficacy of Liposomal Bupivacaine Following Pericapsular Nerve Group (PENG) Block in Patients with Hip Fracture: A Randomized Controlled Observer-Blinded Study
Single-injection pericapsular nerve group (PENG) block with ropivacaine provides clear analgesic effects in preoperative p...
A Decades-Long Journey of Palmitoylethanolamide (PEA) for Chronic Neuropathic Pain Management: A Comprehensive Narrative Review
A Decades-Long Journey of Palmitoylethanolamide (PEA) for Chronic Neuropathic Pain Management: A Comprehensive Narrative Review
Palmitoylethanolamide (PEA) has been prescribed in neuropathic pain management for over 20 years. This study aims...
The Global Burden of Migraine: A 30-Year Trend Review and Future Projections by Age, Sex, Country, and Region
The Global Burden of Migraine: A 30-Year Trend Review and Future Projections by Age, Sex, Country, and Region
Migraine is a prevalent neurological disorder causing significant disability worldwide. Despite extensive research on spec...
Ultrasound-Guided Thoracic Paravertebral Injection of Platelet-Rich Plasma for the Treatment of Thoracic Herpes Zoster-Related Pain: A Study Protocol
Ultrasound-Guided Thoracic Paravertebral Injection of Platelet-Rich Plasma for the Treatment of Thoracic Herpes Zoster-Related Pain: A Study Protocol
Herpes zoster (HZ), triggered by the reactivation of the varicella-zoster virus, manifests as a painful rash known as zost...
The Diagnosis and Management of Meralgia Paresthetica: A Narrative Review
The Diagnosis and Management of Meralgia Paresthetica: A Narrative Review
Meralgia paresthetica (MP) is a sensory mononeuropathy affecting the lateral femoral cutaneous nerve. Diagnosis is typical...
Complementary Approaches to Postoperative Pain Management: A Review of Non-pharmacological Interventions
Complementary Approaches to Postoperative Pain Management: A Review of Non-pharmacological Interventions
Postoperative pain significantly affects many surgical patients. While opioids are crucial for pain management, they come ...
Comparative Evaluation of Cyclooxygenase Inhibition Profiles Across Various NSAID Forms and Doses: Implications for Efficacy and Adverse Effects
Comparative Evaluation of Cyclooxygenase Inhibition Profiles Across Various NSAID Forms and Doses: Implications for Efficacy and Adverse Effects
Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used for pain disorders and exert pharmacological effects by in...
Intercostal Nerve Cryoablation During Lobectomy for Postsurgical Pain: A Safe and Cost-Effective Intervention
Intercostal Nerve Cryoablation During Lobectomy for Postsurgical Pain: A Safe and Cost-Effective Intervention
The cost benefit of intercostal nerve cryoablation during surgical lobectomy for postoperative pain management is unknown....
Endoscopic Epidurolysis for the Management of Chronic Spinal Pain: A Delphi-Based Italian Experts Consensus
Endoscopic Epidurolysis for the Management of Chronic Spinal Pain: A Delphi-Based Italian Experts Consensus
Endoscopic epidurolysis (EE) is a minimally invasive procedure used to manage chronic spinal pain, particularly in cases u...
Potential Role of Focal Microvibration (Equistasi®) in the Management of Chronic Pain: A Pilot Study
Potential Role of Focal Microvibration (Equistasi®) in the Management of Chronic Pain: A Pilot Study
Chronic pain is one of the leading causes of medical consultation with a dramatic psychophysical and socioeconomic impact....
Effect of CT-Guided Repeated Pulsed Radiofrequency on Controlling Acute/Subacute Zoster-Associated Pain: A Retrospective Cohort Study
Effect of CT-Guided Repeated Pulsed Radiofrequency on Controlling Acute/Subacute Zoster-Associated Pain: A Retrospective Cohort Study
Zoster-associated pain (ZAP) treatment and management is still inadequate. Repeated intervention protocol is often applied...
CT-Guided Radiofrequency Ablation Targeting the Herniation Edge of the Cervical Disc for the Treatment of Neck Pain: A Retrospective Study
CT-Guided Radiofrequency Ablation Targeting the Herniation Edge of the Cervical Disc for the Treatment of Neck Pain: A Retrospective Study
Sinuvertebral nerve overactivation is one of the mechanisms of neck pain caused by cervical disc herniation. Radiofrequenc...
Whole-Body Electrostatic Pain Treatment in Adults with Chronic Pain: A Prospective Multicentric Observational Clinical Trial
Whole-Body Electrostatic Pain Treatment in Adults with Chronic Pain: A Prospective Multicentric Observational Clinical Trial
In the treatment of patients with chronic pain, whole-body electrostatic therapy using the Elosan Cabin C1 has been propos...
Glycosaminoglycan Replacement Therapy with Intravesical Instillations of Combined Hyaluronic Acid and Chondroitin Sulfate in Patients with Recurrent Cystitis, Post-radiation Cystitis and Bladder Pain Syndrome: A Narrative Review
Glycosaminoglycan Replacement Therapy with Intravesical Instillations of Combined Hyaluronic Acid and Chondroitin Sulfate in Patients with Recurrent Cystitis, Post-radiation Cystitis and Bladder Pain Syndrome: A Narrative Review
Defects in the glycosaminoglycan layer (GAG) of the bladder mucosa have been identified as a significant contributor to th...
Progress in Radiofrequency Therapy for Zoster-Associated Pain About Parameters, Modes, Targets, and Combined Therapy: A Narrative Review
Progress in Radiofrequency Therapy for Zoster-Associated Pain About Parameters, Modes, Targets, and Combined Therapy: A Narrative Review
Zoster-associated pain (ZAP) is a painful condition that significantly impacts a patient’s quality of life, often le...
Temporary Peripheral Nerve Stimulation as Treatment for Chronic Pain
Temporary Peripheral Nerve Stimulation as Treatment for Chronic Pain
Chronic pain is a growing problem across the world, and in the midst of an opioid epidemic, it is imperative that alternat...
Combined Efficacy of Systemically Acting Diclofenac Sodium Patch and Alpha-2-Delta Calcium Channel Ligand in Chronic Low Back Pain: Subanalysis of a Phase III Study
Combined Efficacy of Systemically Acting Diclofenac Sodium Patch and Alpha-2-Delta Calcium Channel Ligand in Chronic Low Back Pain: Subanalysis of a Phase III Study
Chronic low back pain often comprises mixed pain types and involves multiple factors. Therefore, we hypothesized that the ...
Letter to the Editor Regarding ‘Deep Neuromuscular Block Attenuates Chronic Postsurgical Pain and Enhances Long-Term Postoperative Recovery After Spinal Surgery: A Randomized Controlled Trial’
Letter to the Editor Regarding ‘Deep Neuromuscular Block Attenuates Chronic Postsurgical Pain and Enhances Long-Term Postoperative Recovery After Spinal Surgery: A Randomized Controlled Trial’
With profound interest we read the article by Tang et al. published in the August iss...
“I’m Not the Same Person Anymore”: Thematic Analysis Exploring Experiences of Dependence to Prescribed Analgesics in Patients with Chronic Pain in the UK
“I’m Not the Same Person Anymore”: Thematic Analysis Exploring Experiences of Dependence to Prescribed Analgesics in Patients with Chronic Pain in the UK
The rising issue of dependence to prescribed pain medication for patients with chronic pain has been highlighted in the li...
A Response to: Letter to the Editor Regarding “Deep Neuromuscular Block Attenuates Chronic Postsurgical Pain and Enhances Long-Term Postoperative Recovery After Spinal Surgery: A Randomized Controlled Trial”
A Response to: Letter to the Editor Regarding “Deep Neuromuscular Block Attenuates Chronic Postsurgical Pain and Enhances Long-Term Postoperative Recovery After Spinal Surgery: A Randomized Controlled Trial”
Conflict of Interest Yan Wu, Xihui Tang, Jie Guo, Qingsong Chen, Yu...
Do Electrical Stimulation Devices Reduce Pain and Improve Function?—A Comparative Review
Do Electrical Stimulation Devices Reduce Pain and Improve Function?—A Comparative Review
Multiple forms of electrical stimulation (ES) potentially offer widely varying clinical benefits. Diminished function comm...
Arts Therapy and Its Implications in Chronic Pain Management: A Narrative Review
Arts Therapy and Its Implications in Chronic Pain Management: A Narrative Review
Chronic nonmalignant pain is recognized as a complex, dynamic, phenomenological interplay between biological, psychologica...
Promising Subjective and Objective Benefits of Modified Mindfulness-Based Stress Reduction Training for Chinese Adults with Chronic Pain: A Pilot Randomized Control Study
Promising Subjective and Objective Benefits of Modified Mindfulness-Based Stress Reduction Training for Chinese Adults with Chronic Pain: A Pilot Randomized Control Study
Mindfulness-based stress reduction (MBSR) has demonstrated its effectiveness in reducing pain-related stress in adults wit...
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