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Chinese Stroke Association guidelines for clinical management of ischaemic cerebrovascular diseases: executive summary and 2023 update
Chinese Stroke Association guidelines for clinical management of ischaemic cerebrovascular diseases: executive summary and 2023 update
HighlightsThe clinical management of ischaemic cerebrovascular diseases comprises a total of 287 recommendations, includin...
Comparing a novel Catfish flow restoration device and the Solitaire stent retriever for thrombectomy revascularisation in emergent largevessel occlusion stroke: a prospective randomised controlled study
Comparing a novel Catfish flow restoration device and the Solitaire stent retriever for thrombectomy revascularisation in emergent largevessel occlusion stroke: a prospective randomised controlled study
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYThere are many distinct kinds o...
Photochemically induced thalamus infarction impairs cognition in a mouse model
Photochemically induced thalamus infarction impairs cognition in a mouse model
IntroductionSmall subcortical infarct, commonly known as lacunar infarct, mostly results from ischaemia in the territory o...
Somatic GJA4 mutation in intracranial extra-axial cavernous hemangiomas
Somatic GJA4 mutation in intracranial extra-axial cavernous hemangiomas
IntroductionExtra-axial cavernous hemangiomas (ECHs) are rare intracranial lesions,1 mostly in the cavernous sinus (repres...
Preclinical evaluation of ZL006-05, a new antistroke drug with fast-onset antidepressant and anxiolytic effects
Preclinical evaluation of ZL006-05, a new antistroke drug with fast-onset antidepressant and anxiolytic effects
IntroductionTo date, stroke remained the second-leading cause of death and one of the leading causes of disability in much...
Enhanced liver X receptor signalling reduces brain injury and promotes tissue regeneration following experimental intracerebral haemorrhage: roles of microglia/macrophages
Enhanced liver X receptor signalling reduces brain injury and promotes tissue regeneration following experimental intracerebral haemorrhage: roles of microglia/macrophages
IntroductionIntracerebral haemorrhage (ICH) accounts for 12%–20% of all types of stroke with over 2 million individuals wo...
Development of machine learning-based models to predict 10-year risk of cardiovascular disease: a prospective cohort study
Development of machine learning-based models to predict 10-year risk of cardiovascular disease: a prospective cohort study
WHAT IS ALREADY KNOWN ON THIS TOPICSeveral cardiovascular diseases (CVD) prediction models have been developed to deliver ...
Prestroke physical activity is associated with admission haematoma volume and the clinical outcome of intracerebral haemorrhage
Prestroke physical activity is associated with admission haematoma volume and the clinical outcome of intracerebral haemorrhage
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSEngaging in regular, light physical activity prior to experiencing ...
Detailed phenotype of RNF213 p.R4810K variant identified by the Chinese patients with acute ischaemic stroke or transient ischaemic attack
Detailed phenotype of RNF213 p.R4810K variant identified by the Chinese patients with acute ischaemic stroke or transient ischaemic attack
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSThis study first identified the RNF213 p.R4810K variant was associa...
Cerebral haemodynamics in symptomatic intracranial atherosclerotic disease: a narrative review of the assessment methods and clinical implications
Cerebral haemodynamics in symptomatic intracranial atherosclerotic disease: a narrative review of the assessment methods and clinical implications
IntroductionIntracranial atherosclerotic disease (ICAD) is a common cause of ischaemic stroke and transient ischaemic atta...
Loss of life expectancy due to stroke and its subtypes in urban and rural areas in China, 2005-2020
Loss of life expectancy due to stroke and its subtypes in urban and rural areas in China, 2005-2020
Materials and methodsData sourceData for mortality of stroke and its subtypes were obtained from the NMSS in China, which ...
Blood pressure-related white matter microstructural disintegrity and associated cognitive function impairment in asymptomatic adults
Blood pressure-related white matter microstructural disintegrity and associated cognitive function impairment in asymptomatic adults
IntroductionBlood pressure (BP) is a major risk factor for cerebrovascular disease.1 Asymptomatic brain pathologies found ...
Long-term functional outcomes improved with deep brain stimulation in patients with disorders of consciousness
Long-term functional outcomes improved with deep brain stimulation in patients with disorders of consciousness
IntroductionDisorders of consciousness (DoCs) are neuropsychiatric disturbances in arousal and awareness that are commonly...
Retinal microvascular signs and recurrent vascular events in patients with TIA or minor stroke
Retinal microvascular signs and recurrent vascular events in patients with TIA or minor stroke
IntroductionMicrovascular changes of the retina have been linked to a higher risk of incidental ischaemic stroke as well a...
Characteristics of intracranial plaque in patients with non-cardioembolic stroke and intracranial large vessel occlusion
Characteristics of intracranial plaque in patients with non-cardioembolic stroke and intracranial large vessel occlusion
What is already known on this topicThe characteristics of intracranial plaque proximal to large vessel occlusion (LVO) in ...
Efficacy and safety of early anticoagulation after endovascular treatment in patients with atrial fibrillation
Efficacy and safety of early anticoagulation after endovascular treatment in patients with atrial fibrillation
IntroductionIn acute ischaemic stroke (AIS) with large vessel occlusion (LVO), endovascular treatment (EVT) has become one...
Comparison of carotid endarterectomy and repeated carotid angioplasty and stenting for in-stent restenosis (CERCAS trial): a randomised study
Comparison of carotid endarterectomy and repeated carotid angioplasty and stenting for in-stent restenosis (CERCAS trial): a randomised study
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSBoth carotid endarterectomy and repeat percutaneous transluminal an...
Group 2 innate lymphoid cells resolve neuroinflammation following cerebral ischaemia
Group 2 innate lymphoid cells resolve neuroinflammation following cerebral ischaemia
IntroductionInflammation and immune responses are the main events in the pathological process following strokes.1 2 The ce...
Impaired glymphatic system as evidenced by low diffusivity along perivascular spaces is associated with cerebral small vessel disease: a population-based study
Impaired glymphatic system as evidenced by low diffusivity along perivascular spaces is associated with cerebral small vessel disease: a population-based study
IntroductionCerebral small vessel disease (CSVD) is a whole-brain disorder that mainly damages small brain vessels and is ...
Correction: Indobufen versus aspirin in acute ischaemic stroke (INSURE): rationale and design of a multicentre randomised trial
Correction: Indobufen versus aspirin in acute ischaemic stroke (INSURE): rationale and design of a multicentre randomised trial
Pan Y, Meng X, Chen W, et al. Indobufen versus aspirin in acute ischaemic stroke (INSURE): rationale and design of a multi...
Antithrombotic therapy in patients with COVID-19: indications, pharmacotherapy and controversy
Antithrombotic therapy in patients with COVID-19: indications, pharmacotherapy and controversy
Hypercoagulability associated with COVID-19 infection increases risks for either venous or arterial thrombotic events (ATE...
Arteriolosclerosis differs from venular collagenosis in relation to cerebrovascular parenchymal damages: an autopsy-based study
Arteriolosclerosis differs from venular collagenosis in relation to cerebrovascular parenchymal damages: an autopsy-based study
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYIntroductionCerebrovascular par...
Association between statin therapy and the risk of stroke in patients with moyamoya disease: a nationwide cohort study
Association between statin therapy and the risk of stroke in patients with moyamoya disease: a nationwide cohort study
IntroductionMoyamoya disease (MMD) is a rare cerebrovascular disease characterised by progressive non-atherosclerotic sten...
Differences in left and right carotid plaque vulnerability in patients with bilateral carotid plaques: a CARE-II study
Differences in left and right carotid plaque vulnerability in patients with bilateral carotid plaques: a CARE-II study
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYBackgroundAtherosclerosis occur...
Acute right insular ischaemic lesions and poststroke left ventricular dysfunction
Acute right insular ischaemic lesions and poststroke left ventricular dysfunction
WHAT IS ALREADY KNOWN ON THIS TOPICMyocardial injury is related to acute ischaemic stroke even without prior cardiac disea...
Angioarchitecture and prognosis of pediatric intracranial pial arteriovenous fistula
Angioarchitecture and prognosis of pediatric intracranial pial arteriovenous fistula
IntroductionPial arteriovenous fistula (PAVF) is a rare intracranial vascular disease defined as a direct pathological con...
Mechanical thrombectomy with combined stent retriever and contact aspiration versus stent retriever alone for acute large vessel occlusion: data from ANGEL-ACT registry
Mechanical thrombectomy with combined stent retriever and contact aspiration versus stent retriever alone for acute large vessel occlusion: data from ANGEL-ACT registry
MethodsStudy populationFrom November 2017 to March 2019, the Endovascular Treatment Key Technique and Emergency Work Flow ...
Haemorrhage risk of brain arteriovenous malformation during pregnancy and puerperium
Haemorrhage risk of brain arteriovenous malformation during pregnancy and puerperium
IntroductionBrain arteriovenous malformation (bAVM) is a relatively rare disease with an estimated incidence of approximat...
Homocysteine impedes neurite outgrowth recovery after intracerebral haemorrhage by downregulating pCAMK2A
Homocysteine impedes neurite outgrowth recovery after intracerebral haemorrhage by downregulating pCAMK2A
IntroductionAffecting 2 million people worldwide each year, intracerebral haemorrhage (ICH) is a serious type of stroke, a...
Roles of light transmission aggregometry and CYP2C19 genotype in predicting ischaemic complications during interventional therapy for intracranial aneurysms
Roles of light transmission aggregometry and CYP2C19 genotype in predicting ischaemic complications during interventional therapy for intracranial aneurysms
IntroductionEndovascular therapy is currently one of the most commonly used methods of treating unruptured intracranial an...
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