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SCI Abstract
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Advances and challenges in the treatment of myasthenia gravis
Myasthenia gravis (MG) is a chronic autoimmune disease with fluctuating muscle weakness and fatigability. Standard immunom...
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Adverse events of rituximab in neuromyelitis optica spectrum disorder: a systematic review and meta-analysis
Background:The adverse events (AEs) of rituximab (RTX) for neuromyelitis optica spectrum disorder (NMOSD) are incompletely...
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Anti-GFAP-antibody positive postinfectious acute cerebellar ataxia and myoclonus after COVID-19: a case report
We present a case of acute cerebellar ataxia and myoclonus with detected anti-GFAP-antibodies in a patient recently recove...
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Subcutaneous cladribine to treat multiple sclerosis: experience in 208 patients
Objective:To report on safety and effectiveness of subcutaneous cladribine (Litak®) in multiple sclerosis (MS) patients.Me...
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Radiomics-based prediction of hemorrhage expansion among patients with thrombolysis/thrombectomy related-hemorrhagic transformation using machine learning
Introduction:Patients with hemorrhagic transformation (HT) were reported to have hemorrhage expansion. However, identifica...
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Validation of a shortened FAST-ED algorithm for smartphone app guided stroke triage
Background and Purpose:Large vessel occlusion (LVO) recognition scales were developed to identify patients with LVO-relate...
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Advances in dementia with Lewy bodies
Dementia with Lewy bodies (DLB) is a clinical diagnosis representing a specific presentation of a pathological α-synuclein...
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The German Multiple Sclerosis and Pregnancy Registry: rationale, objective, design, and first results
Objectives:Multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD) predominantly affect women of repro...
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Comment on: Clinico-radiologic features and therapeutic strategies in tumefactive demyelination: a retrospective analysis of 50 consecutive cases
1. Vakrakou, AG, Tzanetakos, D, Evangelopoulos, ME, et al. Clinico-radiologic features and therapeutic strategies in tumef...
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FAST-ED scale smartphone app-based prediction of large vessel occlusion in suspected stroke by emergency medical service
Background and Purpose:Considering the highly time-dependent therapeutic effect of endovascular treatment in patients with...
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A systematic review of relapse rates during pregnancy and postpartum in patients with relapsing multiple sclerosis
Introduction:Pregnancy is widely accepted as a period when relapses of multiple sclerosis (MS) are decreased, with an incr...
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Efficacy and safety of immunosuppressive therapy in myelin oligodendrocyte glycoprotein antibody–associated disease: a systematic review and meta-analysis
Background:A considerable number of patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) ...
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Surgical outcome and prognostic factors in spinal cord ependymoma: a single-center, long-term follow-up study
Objective:Spinal cord ependymomas account for 3–6% of all central nervous system tumors and around 60% of all intramedulla...
Therapeutic Advances In Neurological Disorders
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Longitudinal treatment responsiveness on plasma neurofilament light chain and glial fibrillary acidic protein levels in neuromyelitis optica spectrum disorder
Background:Neurofilament light chain (NfL) and glial fibrilliary acidic protein (GFAP) have been suggested to be biomarker...
Therapeutic Advances In Neurological Disorders
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Corrigendum to “Safety and effectiveness of eculizumab in Japanese patients with generalized myasthenia gravis: interim analysis of post-marketing surveillance”
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Association of serum neurofilament light chain levels and neuropsychiatric manifestations in systemic lupus erythematosus
Background:The aim was to evaluate the diagnostic potential of serum neurofilament light chain (sNfL) measurements in pati...
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Secondary mechanisms of injury and viable pathophysiological targets in intracerebral hemorrhage
Intracerebral hemorrhage (ICH) can be divided into a primary and secondary phase. In the primary phase, hematoma volume is...
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Response to antiseizure medications in epileptic patients with malformation of cortical development
Background:Malformation of cortical development (MCD) is one of the most common causes of pharmacoresistant epilepsy. Impr...
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Cyclophosphamide in highly aggressive Marburg-like multiple sclerosis
1. Vakrakou, AG, Tzanetakos, D, Evangelopoulos, ME, et al. Clinico-radiologic features and therapeutic strategies in tumef...
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Treatment patterns in pediatric patients with multiple sclerosis in Germany—a nationwide claim-based analysis
Background:The manifestation of multiple sclerosis (MS) in childhood and adolescence occurs in 3%−5% of all MS cases. Howe...
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Predictors of adherence and persistence to disease-modifying therapies in Multiple Sclerosis
Background and Aims:In multiple sclerosis (MS), non-adherence/non-persistence is related to suboptimal response to treatme...
Therapeutic Advances In Neurological Disorders
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No evidence for loss of natalizumab effectiveness with every-6-week dosing: a propensity score–matched comparison with every-4-week dosing in patients enrolled in the Tysabri Observational Program (TOP)
Background:Extended interval dosing of natalizumab is associated with significantly lower progressive multifocal leukoence...
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Efficacy and tolerability of antiseizure drugs
Drug-resistant epilepsy occurs in 25–30% of patients. Furthermore, treatment with a first-generation antiseizure drug (ASD...
Therapeutic Advances In Neurological Disorders
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Glycemic variability of acute stroke patients and clinical outcomes: a continuous glucose monitoring study
Introduction:Glycemic variability (GV) has been associated with worse prognosis in critically ill patients. We sought to e...
Therapeutic Advances In Neurological Disorders
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Erratum to “A propensity-matched comparison of long-term disability worsening in patients with multiple sclerosis treated with dimethyl fumarate or fingolimod”
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Therapeutic Advances In Neurological Disorders
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MRI as a first-line imaging modality in acute ischemic stroke: a sustainable concept
Background:Computed tomography (CT) scans are the first-line imaging technique in acute stroke patients based on the argum...
Therapeutic Advances In Neurological Disorders
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Non-invasive markers of liver fibrosis and outcome in large vessel occlusion stroke
Background:Liver fibrosis has been identified as an outcome predictor in cardiovascular disease and has been associated wi...
Therapeutic Advances In Neurological Disorders
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Do somatosensory deficits predict efficacy of neurorehabilitation using neuromuscular electrical stimulation for moderate to severe motor paralysis of the upper limb in chronic stroke?
Background:Various neurorehabilitation programs have been developed to promote recovery from motor impairment of upper ext...
Therapeutic Advances In Neurological Disorders
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Treatment approaches to patients with multiple sclerosis and coexisting autoimmune disorders
The past decades have yielded major therapeutic advances in many autoimmune conditions – such as multiple sclerosis (MS) –...
Therapeutic Advances In Neurological Disorders
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A novel score for evaluating cerebral aneurysms treated with flow diversion: 4F-flow diversion predictive score
Background and purpose:Although grading scales for angiography outcomes following cerebral aneurysm treatment with flow di...
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