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Moving with the Times: The Health Science Alliance (HSA) Biobank, Pathway to Sustainability
Moving with the Times: The Health Science Alliance (HSA) Biobank, Pathway to Sustainability
Human biobanks are recognised as vital components of translational research infrastructure. With the growth in personalise...
Cytokine Profiling in Plasma from Patients with Brain Tumors Versus Healthy Individuals using 2 Different Multiplex Immunoassay Platforms
Cytokine Profiling in Plasma from Patients with Brain Tumors Versus Healthy Individuals using 2 Different Multiplex Immunoassay Platforms
We compared the performance of two 96-well multiplex immunoassay platforms in assessing plasma cytokine concentrations in ...
Quality Considerations When Using Tissue Samples for Biomarker Studies in Cancer Research
Quality Considerations When Using Tissue Samples for Biomarker Studies in Cancer Research
Tissue obtained from biobanks is frequently employed in biomarker studies. Biomarkers define objective, measurable charact...
The Assessment of the Usefulness of Selected Markers in the Diagnosis of Chronic Kidney Disease in Children
The Assessment of the Usefulness of Selected Markers in the Diagnosis of Chronic Kidney Disease in Children
Introduction:The kidney deterioration, which starts in childhood often leads to end-stage renal failure in the future. The...
Mind Over Matter: Confronting Challenges in Post-Mortem Brain Biobanking for Glioblastoma Multiforme
Mind Over Matter: Confronting Challenges in Post-Mortem Brain Biobanking for Glioblastoma Multiforme
Over the past 10 years, there has been limited progress for the treatment of brain cancer and outcomes for patients are no...
Multiple Sclerosis Biomarker Discoveries by Proteomics and Metabolomics Approaches
Multiple Sclerosis Biomarker Discoveries by Proteomics and Metabolomics Approaches
Multiple sclerosis (MS) is an autoimmune inflammatory disorder of the central nervous system (CNS) resulting in demyelinat...
Circadian, Week-to-Week, and Physical Exercise-Induced Variation of Serum Microfibrillar-Associated Protein 4
Circadian, Week-to-Week, and Physical Exercise-Induced Variation of Serum Microfibrillar-Associated Protein 4
Serum microfibrillar-associated protein 4 (sMFAP4) has been investigated as a biomarker for various diseases and is demons...
Companion Diagnostics: State of the Art and New Regulations
Companion Diagnostics: State of the Art and New Regulations
Companion diagnostics (CDx) hail promise of improving the drug development process and precision medicine. However, there ...
Prognostic Utility of Pretreatment Neutrophil-Lymphocyte Ratio in Advanced Larynx Cancer
Prognostic Utility of Pretreatment Neutrophil-Lymphocyte Ratio in Advanced Larynx Cancer
Purpose:Neutrophil-lymphocyte ratio has been explored as a prognosticator in several cancer types, but its association wit...
Advancing the Care of Pancreatic Cancer Patients: Moving Beyond Just Tumour Tissue
Advancing the Care of Pancreatic Cancer Patients: Moving Beyond Just Tumour Tissue
Biobanking efforts, to establish and grow the pool of available tissue from which evidence on aetiology, therapeutic susce...
Serum Neurofilament Light as a Biomarker of Traumatic Brain Injury in the Presence of Concomitant Peripheral Injury
Serum Neurofilament Light as a Biomarker of Traumatic Brain Injury in the Presence of Concomitant Peripheral Injury
Introduction:Serum neurofilament light (NfL) is an emerging biomarker of traumatic brain injury (TBI). However, the effect...
suPAR Cut-Offs for Risk Stratification in Patients With Symptoms of COVID-19
suPAR Cut-Offs for Risk Stratification in Patients With Symptoms of COVID-19
Objectives:Elevated soluble urokinase Plasminogen Activator Receptor (suPAR) is a biomarker associated with adverse outcom...
Update on Biomarkers in Spinal Muscular Atrophy
Update on Biomarkers in Spinal Muscular Atrophy
The availability of disease modifying therapies for spinal muscular atrophy (SMA) has created an urgent need to identify c...
Prognostic Value of Inflammatory Biomarkers in Patients with Severe COVID-19: A Single-Center Retrospective Study
Prognostic Value of Inflammatory Biomarkers in Patients with Severe COVID-19: A Single-Center Retrospective Study
Background:The current knowledge about novel coronavirus-2019 (COVID-19) indicates that the immune system and inflammatory...
IL-6 and Other Biomarkers associated with Poor Prognosis in a Cohort of Hospitalized Patients with COVID-19 in Madrid
IL-6 and Other Biomarkers associated with Poor Prognosis in a Cohort of Hospitalized Patients with COVID-19 in Madrid
Objectives:There are several published works on the prognostic value of biomarkers in relation to the severity or fatal ou...
Extracellular Vesicle Proteome of Breast Cancer Patients with and Without Cognitive Impairment Following Anthracycline-based Chemotherapy: An Exploratory Study
Extracellular Vesicle Proteome of Breast Cancer Patients with and Without Cognitive Impairment Following Anthracycline-based Chemotherapy: An Exploratory Study
Cognitive impairment due to cancer and its therapy is a major concern among cancer patients and survivors. Extracellular v...
Effect of Methylprednisolone on Inflammation and Coagulation in Patients with Severe COVID-19: A Retrospective Cohort Study
Effect of Methylprednisolone on Inflammation and Coagulation in Patients with Severe COVID-19: A Retrospective Cohort Study
Corticosteroids reduced mortality rate in patients with coronavirus disease 2019 (COVID-19). Previously, we hypothesized t...
Building Research Support Capacity across Human Health Biobanks during the COVID-19 Pandemic
Building Research Support Capacity across Human Health Biobanks during the COVID-19 Pandemic
Human health biobanks are forms of research infrastructure that supply biospecimens and associated data to researchers, an...
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