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The mediating effect of perceived stress on the relationship between big five personality traits and suboptimal health status in Chinese population: a nationwide survey in the framework of predictive, preventive, and personalized medicine
The mediating effect of perceived stress on the relationship between big five personality traits and suboptimal health status in Chinese population: a nationwide survey in the framework of predictive, preventive, and personalized medicine
The effects of psychological factors on suboptimal health status (SHS) have been widely described; however, mechanisms beh...
Automated detection of nine infantile fundus diseases and conditions in retinal images using a deep learning system
Automated detection of nine infantile fundus diseases and conditions in retinal images using a deep learning system
We developed an Infant Retinal Intelligent Diagnosis System (IRIDS), an automated system to aid early diagnosis and monito...
Frailty mediating the causality between leucocyte telomere length and mortality: a cohort study of 440,551 UK Biobank participants
Frailty mediating the causality between leucocyte telomere length and mortality: a cohort study of 440,551 UK Biobank participants
Previous studies reported leucocyte telomere length (LTL) and frailty were associated with mortality, but it remains uncle...
Cancer screening in hospitalized ischemic stroke patients: a multicenter study focused on multiparametric analysis to improve management of occult cancers
Cancer screening in hospitalized ischemic stroke patients: a multicenter study focused on multiparametric analysis to improve management of occult cancers
The reciprocal promotion of cancer and stroke occurs due to changes in shared risk factors, such as metabolic pathways and...
Nitroproteomics is instrumental for stratification and targeted treatments of astrocytoma patients: expert recommendations for advanced 3PM approach with improved individual outcomes
Nitroproteomics is instrumental for stratification and targeted treatments of astrocytoma patients: expert recommendations for advanced 3PM approach with improved individual outcomes
Protein tyrosine nitration is a selectively and reversible important post-translational modification, which is closely rel...
Impacts of a multipurpose outpatient hospital pharmacy in the framework of 3P medicine
Impacts of a multipurpose outpatient hospital pharmacy in the framework of 3P medicine
In recent years, we have been witnessing a change in the performance of hospital pharmacists, aimed at increasing their pa...
Diabetes, glycemic control and arterial stiffness: a real-world cohort study in the context of predictive, preventive, and personalized medicine
Diabetes, glycemic control and arterial stiffness: a real-world cohort study in the context of predictive, preventive, and personalized medicine
Arterial stiffness is a major contributor to morbidity and mortality worldwide. Although several metabolic markers associa...
The predictive, preventive, and personalized medicine of insomnia: gut microbiota and inflammation
The predictive, preventive, and personalized medicine of insomnia: gut microbiota and inflammation
The human gut microbiota (GM) has been recognized as a significant factor in the development of insomnia, primarily throug...
Emerging frontiers of artificial intelligence and machine learning in ischemic stroke: a comprehensive investigation of state-of-the-art methodologies, clinical applications, and unraveling challenges
Emerging frontiers of artificial intelligence and machine learning in ischemic stroke: a comprehensive investigation of state-of-the-art methodologies, clinical applications, and unraveling challenges
At present, stroke remains the second highest cause of death globally and a leading cause of disability. From 1990 to 2019...
Predicting 1-, 3-, 5-, and 8-year all-cause mortality in a community-dwelling older adult cohort: relevance for predictive, preventive, and personalized medicine
Predicting 1-, 3-, 5-, and 8-year all-cause mortality in a community-dwelling older adult cohort: relevance for predictive, preventive, and personalized medicine
Population aging is a global public health issue involving increased prevalence of age-related diseases, and concomitant b...
Conceptualised psycho-medical footprint for health status outcomes and the potential impacts for early detection and prevention of chronic diseases in the context of 3P medicine
Conceptualised psycho-medical footprint for health status outcomes and the potential impacts for early detection and prevention of chronic diseases in the context of 3P medicine
The Suboptimal Health Status Questionnaire-25 (SHSQ-25) is a distinctive medical psychometric diagnostic tool designed for...
Artificial intelligence to improve ischemia prediction in Rubidium Positron Emission Tomography—a validation study
Artificial intelligence to improve ischemia prediction in Rubidium Positron Emission Tomography—a validation study
Patients are referred to functional coronary artery disease (CAD) testing based on their pre-test probability (PTP) to sea...
Causal relationship between gut Prevotellaceae and risk of sepsis: a two-sample Mendelian randomization and clinical retrospective study in the framework of predictive, preventive, and personalized medicine
Causal relationship between gut Prevotellaceae and risk of sepsis: a two-sample Mendelian randomization and clinical retrospective study in the framework of predictive, preventive, and personalized medicine
Gut microbiota is closely related to sepsis. Recent studies have suggested that Prevotellaceae could be associated with in...
Development and validation of a short-form suboptimal health status questionnaire
Development and validation of a short-form suboptimal health status questionnaire
Suboptimal health status (SHS) is a reversible, borderline state between optimal health and disease. Although this conditi...
Identification of novel serum protein biomarkers in the context of 3P medicine for intravenous leiomyomatosis: a data-independent acquisition mass spectrometry-based proteomics study
Identification of novel serum protein biomarkers in the context of 3P medicine for intravenous leiomyomatosis: a data-independent acquisition mass spectrometry-based proteomics study
Intravenous leiomyomatosis (IVL) is a rare endocrine-associated tumor with unique characteristics of intravascular invasio...
Machine learning–couched treatment algorithms tailored to individualized profile of patients with primary anterior chamber angle closure predisposed to the glaucomatous optic neuropathy
Machine learning–couched treatment algorithms tailored to individualized profile of patients with primary anterior chamber angle closure predisposed to the glaucomatous optic neuropathy
Primary angle closure glaucoma (PACG) is still one of the leading causes of irreversible blindness, with a trend towards a...
Quantitative phosphoproteomics reveals molecular pathway network alterations in human early-stage primary hepatic carcinomas: potential for 3P medical approach
Quantitative phosphoproteomics reveals molecular pathway network alterations in human early-stage primary hepatic carcinomas: potential for 3P medical approach
Hepatic carcinoma is one of the most common types of malignant tumors in the digestive system, and its biological characte...
The correlation between primary open-angle glaucoma (POAG) and gut microbiota: a pilot study towards predictive, preventive, and personalized medicine
The correlation between primary open-angle glaucoma (POAG) and gut microbiota: a pilot study towards predictive, preventive, and personalized medicine
Glaucoma is the leading cause of irreversible blindness worldwide. Emerged evidence has shown that glaucoma is considered ...
Identifying oxidative stress-related biomarkers in idiopathic pulmonary fibrosis in the context of predictive, preventive, and personalized medicine using integrative omics approaches and machine-learning strategies
Identifying oxidative stress-related biomarkers in idiopathic pulmonary fibrosis in the context of predictive, preventive, and personalized medicine using integrative omics approaches and machine-learning strategies
Idiopathic pulmonary fibrosis (IPF) is a rare interstitial lung disease with a poor prognosis that currently lacks effecti...
Royal jelly: a predictive, preventive and personalised strategy for novel treatment options in non-communicable diseases
Royal jelly: a predictive, preventive and personalised strategy for novel treatment options in non-communicable diseases
Royal jelly (RJ) is a bee product produced by young adult worker bees, composed of water, proteins, carbohydrates and lipi...
COVID-19 lessons to protect populations against future pandemics by implementing PPPM principles in healthcare
COVID-19 lessons to protect populations against future pandemics by implementing PPPM principles in healthcare
The coronavirus disease 2019 (COVID-19) pandemic has continued for more than 3 years, placing a huge burden on so...
Anatomic characteristics of shoulder based on MRI accurately predict incomplete rotator cuff injuries in patients: relevance for predictive, preventive, and personalized healthcare strategies
Anatomic characteristics of shoulder based on MRI accurately predict incomplete rotator cuff injuries in patients: relevance for predictive, preventive, and personalized healthcare strategies
In the diagnosis of incomplete rotator cuff injuries (IRCI), magnetic resonance imaging (MRI) and ultrasound examination o...
Genetically predicted the causal relationship between gut microbiota and infertility: bidirectional Mendelian randomization analysis in the framework of predictive, preventive, and personalized medicine
Genetically predicted the causal relationship between gut microbiota and infertility: bidirectional Mendelian randomization analysis in the framework of predictive, preventive, and personalized medicine
Several studies have reported the association between gut microbiota and infertility; however, the causal association betw...
Ubiquitinomics revealed disease- and stage-specific patterns relevant for the 3PM approach in human sigmoid colon cancers
Ubiquitinomics revealed disease- and stage-specific patterns relevant for the 3PM approach in human sigmoid colon cancers
The patients with sigmoid colorectal cancer commonly show high mortality and poor prognosis. Increasing evidence has demon...
Growth hormone proteoformics atlas created to promote predictive, preventive, and personalized approach in overall management of pituitary neuroendocrine tumors
Growth hormone proteoformics atlas created to promote predictive, preventive, and personalized approach in overall management of pituitary neuroendocrine tumors
Human growth hormone (GH) is the indispensable hormone for the maintenance of normal physiological functions of the human ...
Quality of life and cost-effectiveness of different breast cancer surgery procedures: a Markov decision tree-based approach in the framework of Predictive, Preventive, and Personalized Medicine
Quality of life and cost-effectiveness of different breast cancer surgery procedures: a Markov decision tree-based approach in the framework of Predictive, Preventive, and Personalized Medicine
Breast cancer is a complex disease with heterogeneous outcomes that may benefit from the implementation of Predictive, Pre...
Mechanical power normalized to aerated lung predicts noninvasive ventilation failure and death and contributes to the benefits of proning in COVID-19 hypoxemic respiratory failure
Mechanical power normalized to aerated lung predicts noninvasive ventilation failure and death and contributes to the benefits of proning in COVID-19 hypoxemic respiratory failure
Concern exists that noninvasive ventilation (NIV) may promote ventilation-induced lung injury(VILI) and worsen outcome in ...
Multi-omics identification of an immunogenic cell death-related signature for clear cell renal cell carcinoma in the context of 3P medicine and based on a 101-combination machine learning computational framework
Multi-omics identification of an immunogenic cell death-related signature for clear cell renal cell carcinoma in the context of 3P medicine and based on a 101-combination machine learning computational framework
Clear cell renal cell carcinoma (ccRCC) is a prevalent urological malignancy associated with a high mortality rate. The la...
Ideal cardiovascular health metrics and life expectancy free of cardiovascular diseases: a prospective cohort study
Ideal cardiovascular health metrics and life expectancy free of cardiovascular diseases: a prospective cohort study
Whether cardiovascular health (CVH) metrics impact longevity with and without cardiovascular diseases (CVDs) has not been ...
Clarifying the effect of gut microbiota on allergic conjunctivitis risk is instrumental for predictive, preventive, and personalized medicine: a Mendelian randomization analysis
Clarifying the effect of gut microbiota on allergic conjunctivitis risk is instrumental for predictive, preventive, and personalized medicine: a Mendelian randomization analysis
Allergic conjunctivitis is an ocular immune disease which affects the conjunctiva, eyelids, and cornea. Growing evidence i...
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