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Dysregulated cholesterol regulatory genes in hepatocellular carcinoma
Dysregulated cholesterol regulatory genes in hepatocellular carcinoma
Cholesterol is an indispensable component in mammalian cells, and cholesterol metabolism performs important roles in vario...
Causal associations between genetically determined common psychiatric disorders and the risk of falls: evidence from Mendelian randomization
Causal associations between genetically determined common psychiatric disorders and the risk of falls: evidence from Mendelian randomization
The causal associations between psychiatric disorders and falls risk remains uncertain. Consequently, this study aimed to ...
Mesenchymal stem cells-derived exosomes: novel carriers for nanoparticle to combat cancer
Mesenchymal stem cells-derived exosomes: novel carriers for nanoparticle to combat cancer
The advancement in novel cancer therapeutics brought a platform combining the properties of exosomes with nanoparticles to...
Differentiation between cerebral alveolar echinococcosis and brain metastases with radiomics combined machine learning approach
Differentiation between cerebral alveolar echinococcosis and brain metastases with radiomics combined machine learning approach
Cerebral alveolar echinococcosis (CAE) and brain metastases (BM) share similar in locations and imaging appearance. Howeve...
Systemic immune-inflammation index (SII) and the risk of all-cause, cardiovascular, and cardio-cerebrovascular mortality in the general population
Systemic immune-inflammation index (SII) and the risk of all-cause, cardiovascular, and cardio-cerebrovascular mortality in the general population
An elevated systemic immune-inflammation index (SII) is associated with higher mortality in patients with coronary artery ...
Comparison of different internal fixation models in ankle arthrodesis using 3D finite-element analysis
Comparison of different internal fixation models in ankle arthrodesis using 3D finite-element analysis
The purpose of this study is to use three-dimensional finite-element analysis to better understand the biomechanical featu...
Association between statin use on delirium and 30-day mortality in patients with chronic obstructive pulmonary disease in the intensive care unit
Association between statin use on delirium and 30-day mortality in patients with chronic obstructive pulmonary disease in the intensive care unit
Delirium occurs frequently in patients with chronic obstructive pulmonary disease in the intensive care unit. Effective pr...
Initiation and rapid titration of methadone and slow-release oral morphine (SROM) in an acute care, inpatient setting: a case series
Initiation and rapid titration of methadone and slow-release oral morphine (SROM) in an acute care, inpatient setting: a case series
Methadone titration in an outpatient setting typically involves initiation with subtherapeutic doses with slow titration t...
Treatment of brainstem and fourth ventricle lesions by the full neuroendoscopic telovelar approach
Treatment of brainstem and fourth ventricle lesions by the full neuroendoscopic telovelar approach
To explore the surgical techniques, advantages, and disadvantages of neuroendoscopic telovelar approach in the treatment o...
Disulfidptosis-related signatures for prognostic and immunotherapy reactivity evaluation in hepatocellular carcinoma
Disulfidptosis-related signatures for prognostic and immunotherapy reactivity evaluation in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most common cancers in the world and a nonnegligible health concern ...
The value of the cinematic volume rendering technique: magnetic resonance imaging in diagnosing tumors associated with the brachial plexus
The value of the cinematic volume rendering technique: magnetic resonance imaging in diagnosing tumors associated with the brachial plexus
To examine the diagnostic advantages and clinical application value of the cinematic volume rendering technique (cVRT) whe...
SNAP25 is a potential target for early stage Alzheimer’s disease and Parkinson’s disease
SNAP25 is a potential target for early stage Alzheimer’s disease and Parkinson’s disease
Alzheimer’s disease (AD) and Parkinson’s disease (PD), two common irreversible neurodegenerative diseases, sha...
Characteristics and outcomes of patients hospitalized for infection with influenza, SARS-CoV-2 or respiratory syncytial virus in the season 2022/2023 in a large German primary care centre
Characteristics and outcomes of patients hospitalized for infection with influenza, SARS-CoV-2 or respiratory syncytial virus in the season 2022/2023 in a large German primary care centre
In 2022/2023, Influenza A and Respiratory Syncytial Virus (RSV) reappeared in hospitalized patients, which was in parallel...
Functional independence, frailty and perceived quality of life in patients who developed delirium during ICU stay: a prospective cohort study
Functional independence, frailty and perceived quality of life in patients who developed delirium during ICU stay: a prospective cohort study
Survivors of critical illness are frequently left with a long-lasting disability. We hypothesised that patients who develo...
Severity of oxidative stress as a hallmark in COVID-19 patients
Severity of oxidative stress as a hallmark in COVID-19 patients
Understanding the mechanisms and identifying effective treatments for the COVID-19 outbreak are imperative. Therefore, thi...
Performance of severity indices for admission and mortality of trauma patients in the intensive care unit: a retrospective cohort study
Performance of severity indices for admission and mortality of trauma patients in the intensive care unit: a retrospective cohort study
Little is known about the performance of severity indices for indicating intensive care and predicting mortality in the In...
A J-shaped relationship between body mass index and the risk of elevated liver stiffness: a cross-sectional study
A J-shaped relationship between body mass index and the risk of elevated liver stiffness: a cross-sectional study
Liver stiffness (LS) is regarded as an indicator of the stages of liver fibrosis and liver cirrhosis. Numerous studies hav...
Adhatoda vasica and Tinospora cordifolia extracts ameliorate clinical and molecular markers in mild COVID-19 patients: a randomized open-label three-armed study
Adhatoda vasica and Tinospora cordifolia extracts ameliorate clinical and molecular markers in mild COVID-19 patients: a randomized open-label three-armed study
SARS-CoV-2 infections caused mild-to-moderate illness. However, a sizable portion of infected people experience a rapid pr...
Validation of non-invasive indicators in the screening of metabolic dysfunction-associated fatty liver disease: a cross-sectional study among Uighurs in rural Xinjiang
Validation of non-invasive indicators in the screening of metabolic dysfunction-associated fatty liver disease: a cross-sectional study among Uighurs in rural Xinjiang
Metabolic dysfunction-associated fatty liver disease (MAFLD) is the most common chronic liver disease in China. Our study ...
Role of advanced glycation end products in diabetic vascular injury: molecular mechanisms and therapeutic perspectives
Role of advanced glycation end products in diabetic vascular injury: molecular mechanisms and therapeutic perspectives
In diabetic metabolic disorders, advanced glycation end products (AGEs) contribute significantly to the development of car...
Clinico-biological-radiomics (CBR) based machine learning for improving the diagnostic accuracy of FDG-PET false-positive lymph nodes in lung cancer
Clinico-biological-radiomics (CBR) based machine learning for improving the diagnostic accuracy of FDG-PET false-positive lymph nodes in lung cancer
The main problem of positron emission tomography/computed tomography (PET/CT) for lymph node (LN) staging is the high fals...
Predicting the prognosis, immune response, and immunotherapy in head and neck squamous cell carcinoma using a novel risk model based on anoikis-related lncRNAs
Predicting the prognosis, immune response, and immunotherapy in head and neck squamous cell carcinoma using a novel risk model based on anoikis-related lncRNAs
Head and neck squamous cell carcinoma (HNSCC) is an extremely heterogeneous and metastatic disease. Anoikis, which is a sp...
Network pharmacology‑based investigation of potential targets of triptonodiol acting on non-small-cell lung cancer
Network pharmacology‑based investigation of potential targets of triptonodiol acting on non-small-cell lung cancer
Triptonodiol is a very promising antitumor drug candidate extracted from the Chinese herbal remedy Tripterygium wilfordii ...
Clinicopathological characteristics and prognosis of medullary thyroid microcarcinoma: a tumor with a similar prognosis to macrocarcinoma
Clinicopathological characteristics and prognosis of medullary thyroid microcarcinoma: a tumor with a similar prognosis to macrocarcinoma
Tumor size plays an important role in the staging and treatment of thyroid carcinoma. A tumor with a maximum diameter of 1...
The FDA-approved anti-amyloid-β monoclonal antibodies for the treatment of Alzheimer’s disease: a systematic review and meta-analysis of randomized controlled trials
The FDA-approved anti-amyloid-β monoclonal antibodies for the treatment of Alzheimer’s disease: a systematic review and meta-analysis of randomized controlled trials
Alzheimer’s disease (AD) is a worldwide public health problem and is difficult to cure. Drugs aimed at slowing the p...
Global cluster analysis and network visualization in cancer-associated fibroblast: insights from Web of Science database from 1999 to 2021
Global cluster analysis and network visualization in cancer-associated fibroblast: insights from Web of Science database from 1999 to 2021
A scientific and comprehensive analysis of the current status and trends in the field of cancer-associated fibroblast (CAF...
The epidemiology of Helicobacter pylori resistance in a university affiliated hospital: a comparison between two time periods—a cross-sectional design
The epidemiology of Helicobacter pylori resistance in a university affiliated hospital: a comparison between two time periods—a cross-sectional design
During the last few decades, the increased use of various types of antibiotics in the general population caused a signific...
Nanotechnology development in surgical applications: recent trends and developments
Nanotechnology development in surgical applications: recent trends and developments
This paper gives a detailed analysis of nanotechnology's rising involvement in numerous surgical fields. We investigat...
Activating transcription factor (ATF) 6 upregulates cystathionine β synthetase (CBS) expression and hydrogen sulfide (H2S) synthesis to ameliorate liver metabolic damage
Activating transcription factor (ATF) 6 upregulates cystathionine β synthetase (CBS) expression and hydrogen sulfide (H2S) synthesis to ameliorate liver metabolic damage
Activating transcription factor 6 (ATF6) is an endoplasmic reticulum stress responsive gene. We previously reported that c...
A landscape on disorders following different COVID-19 vaccination: a systematic review of Iranian case reports
A landscape on disorders following different COVID-19 vaccination: a systematic review of Iranian case reports
There have been massive studies to develop an effective vaccine against SARS-CoV-2 which fortunately led to manage the rec...
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