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Qualitative evaluation of the symptoms and quality of life impacts of long-chain fatty acid oxidation disorders
Qualitative evaluation of the symptoms and quality of life impacts of long-chain fatty acid oxidation disorders
Background:Long-chain fatty acid oxidation disorders (LC-FAOD) are a group of rare autosomal-recessive genetic disorders c...
Lipid ratios and obesity indices are effective predictors of metabolic syndrome in women with polycystic ovary syndrome
Lipid ratios and obesity indices are effective predictors of metabolic syndrome in women with polycystic ovary syndrome
Background:Insulin resistance (IR) is common in women with polycystic ovary syndrome (PCOS). Metabolic syndrome (MS) invol...
Recent advancement in the treatment of boys and adolescents with hypogonadism
Recent advancement in the treatment of boys and adolescents with hypogonadism
Clinical manifestations and the need for treatment varies according to age in males with hypogonadism. Early foetal-onset ...
Metabolic syndrome is associated with prostate enlargement: a systematic review, meta-analysis, and meta-regression on patients with lower urinary tract symptom factors
Metabolic syndrome is associated with prostate enlargement: a systematic review, meta-analysis, and meta-regression on patients with lower urinary tract symptom factors
Background:Metabolic syndrome (MetS) is defined by at least three of the following five criteria: blood pressure ⩾130/85 m...
The influence of gestational hypertension on cord blood adiponectin levels: a case-controlled study
The influence of gestational hypertension on cord blood adiponectin levels: a case-controlled study
Introduction:Gestational hypertension is one of the most common complications of pregnancy and childbirth worldwide and ma...
Decreased serum C1Q/TNF-related protein 4 concentrations are associated with type 2 diabetes mellitus
Decreased serum C1Q/TNF-related protein 4 concentrations are associated with type 2 diabetes mellitus
Objective:To detect serum C1Q/TNF-related protein 4 (CTRP4) concentrations in patients with newly diagnosed type 2 diabete...
Clinical and molecular characterization of thyroid cancer when seen as a second malignant neoplasm
Clinical and molecular characterization of thyroid cancer when seen as a second malignant neoplasm
Background:Second malignant neoplasms (SMN) are among the most serious long-term adverse health conditions in cancer survi...
Novel therapeutic targets and agents for pediatric dyslipidemia
Novel therapeutic targets and agents for pediatric dyslipidemia
Landmark studies have convincingly demonstrated that atherosclerosis begins in youth. While generally asymptomatic, an inc...
Feasibility and acceptance of a virtual multidisciplinary care programme for patients with type 2 diabetes during the COVID-19 pandemic
Feasibility and acceptance of a virtual multidisciplinary care programme for patients with type 2 diabetes during the COVID-19 pandemic
Background and aims:Type 2 diabetes mellitus is one of the major public health concerns. The current lifestyle and advance...
NAFLD in type 1 diabetes: overrated or underappreciated?
NAFLD in type 1 diabetes: overrated or underappreciated?
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in western countries, affecting 25–30% o...
Digital health and diabetes: experience from India
Digital health and diabetes: experience from India
The digitization of healthcare and its usage in the delivery of healthcare have experienced exponential growth across the ...
Impact of TPOAb-negative maternal subclinical hypothyroidism in early pregnancy on adverse pregnancy outcomes
Impact of TPOAb-negative maternal subclinical hypothyroidism in early pregnancy on adverse pregnancy outcomes
Purpose:To investigate the effect of subclinical hypothyroidism on pregnancy outcomes of women early in their pregnancy wi...
The EMRG Consortium: a gate to identify the burden of metabolic (dysfunction)-associated fatty liver disease in Egypt
The EMRG Consortium: a gate to identify the burden of metabolic (dysfunction)-associated fatty liver disease in Egypt
1. Eslam, M, Sarin, SK, Wong, VW, et al The Asian Pacific Association for the Study of the Liver clinical practice guideli...
Designing an integrated, nurse-driven and home-based digital intervention to improve insulin management in under-resourced settings
Designing an integrated, nurse-driven and home-based digital intervention to improve insulin management in under-resourced settings
Background:In South Africa, initiating insulin for people with type 2 diabetes and subsequent titration is a major challen...
Evolution of anaplastic thyroid cancer management: perspectives in the era of precision oncology
Evolution of anaplastic thyroid cancer management: perspectives in the era of precision oncology
Anaplastic thyroid cancer is a rare aggressive malignancy resulting in poor outcomes, including significant morbidity and ...
The importance of physical activity in management of type 2 diabetes and COVID-19
The importance of physical activity in management of type 2 diabetes and COVID-19
Over time, various guidelines have emphasised the importance of physical activity and exercise training in the management ...
Current updates on protein as biomarkers for diabetic kidney disease: a systematic review
Current updates on protein as biomarkers for diabetic kidney disease: a systematic review
Background:In the past decade, researchers have been focused on discovering protein biomarkers for diabetic kidney disease...
Circulating microRNA-194 levels in Chinese patients with diabetic kidney disease: a case–control study
Circulating microRNA-194 levels in Chinese patients with diabetic kidney disease: a case–control study
Objective:MicroRNAs (miRNAs) regulate gene expression and are involved in diabetic kidney disease (DKD) pathogenesis. We i...
Current concept of stress fractures with an additional category of atypical fractures: a perspective review with representative images
Current concept of stress fractures with an additional category of atypical fractures: a perspective review with representative images
Stress fractures have traditionally been classified into three categories: fatigue fractures due to overuse of bone with n...
Alteration of serum neuregulin 4 and neuregulin 1 in gestational diabetes mellitus
Alteration of serum neuregulin 4 and neuregulin 1 in gestational diabetes mellitus
Context:Neuregulin 4 (Nrg4) and neuregulin 1 (Nrg1) have been shown to play vital roles in several disorders of glucose me...
Endotrophin as a novel marker in PCOS and its relation with other adipokines and metabolic parameters: a pilot study
Endotrophin as a novel marker in PCOS and its relation with other adipokines and metabolic parameters: a pilot study
Background:Polycystic ovary syndrome is known to be the most common hormonal disorder in women of reproductive age. Curren...
Medullary thyroid carcinoma: recent advances in identification, treatment, and prognosis
Medullary thyroid carcinoma: recent advances in identification, treatment, and prognosis
Medullary thyroid carcinoma (MTC) is a neuroendocrine tumor that represents <5% of all thyroid malignancies and is gene...
Diabetes mellitus in dialysis and renal transplantation
Diabetes mellitus in dialysis and renal transplantation
Diabetes mellitus is the commonest cause of end-stage kidney failure worldwide and is a proven and significant risk factor...
The prognostic value of thyroid-stimulating immunoglobulin in the management of Graves’ disease
The prognostic value of thyroid-stimulating immunoglobulin in the management of Graves’ disease
Background:The bioassay of thyroid-stimulating immunoglobulin was reported to have a similar performance to the commonly u...
Therapeutics for type-2 diabetes mellitus: a glance at the recent inclusions and novel agents under development for use in clinical practice
Therapeutics for type-2 diabetes mellitus: a glance at the recent inclusions and novel agents under development for use in clinical practice
Diabetes mellitus (DM) is a chronic, progressive, and multifaceted illness resulting in significant physical and psycholog...
Effects of SGLT2 inhibitors on cardiovascular death and all-cause death in patients with type 2 diabetes and chronic kidney disease: an updated meta-analysis including the SCORED trial
Effects of SGLT2 inhibitors on cardiovascular death and all-cause death in patients with type 2 diabetes and chronic kidney disease: an updated meta-analysis including the SCORED trial
Background:The effects of sodium-glucose transporter 2 (SGLT2) inhibitors on cardiovascular death (CV death) and all-cause...
Therapeutic approaches for non-alcoholic steatohepatitis
Therapeutic approaches for non-alcoholic steatohepatitis
Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) have been reported as a novel worldwide...
Sex and ethnic differences in the cardiovascular complications of type 2 diabetes
Sex and ethnic differences in the cardiovascular complications of type 2 diabetes
Diabetes mellitus represents a global health concern affecting 463 million adults and is projected to rapidly rise to 700 ...
A case of adrenal Cushing’s syndrome and primary hyperparathyroidism due to an atypical parathyroid adenoma
A case of adrenal Cushing’s syndrome and primary hyperparathyroidism due to an atypical parathyroid adenoma
Cushing’s syndrome is a rare disorder of cortisol excess and is associated with significant morbidity and mortality. Hyper...
Clinical associations with stage B heart failure in adults with type 2 diabetes
Clinical associations with stage B heart failure in adults with type 2 diabetes
Background:There is a high prevalence of asymptomatic (American Heart Association Stage B) heart failure (SBHF) in people ...
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