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Alpha-melanocyte-stimulating hormone-mediated appetite regulation in the central nervous system
Alpha-melanocyte-stimulating hormone-mediated appetite regulation in the central nervous system
Understanding the complex action mechanism of appetite regulation peptides can significantly impact therapeutic options in...
Changes in Visual Long-term Potentiation Show Preserved Cyclicity in Human Females Taking Combined Oral Contraceptives
Changes in Visual Long-term Potentiation Show Preserved Cyclicity in Human Females Taking Combined Oral Contraceptives
Introduction: The combined oral contraceptive pill (COC) is often employed to address physical and neurological symptoms i...
Variant in the dopamine-4-receptor gene (DRD4) in patients with type 1 diabetes
Variant in the dopamine-4-receptor gene (DRD4) in patients with type 1 diabetes
IIntroduction Because dopaminergic signaling pathways are one of the regulators of autoimmunity, we hypothesize that the -...
Cortexin® Ameliorates High Glucose-Induced Neuropathy in Cultured Rat Sensory Neurons
Cortexin® Ameliorates High Glucose-Induced Neuropathy in Cultured Rat Sensory Neurons
Introduction: The aim of this study was to investigate whether Cortexin®, a brain peptide containing agent, has any m...
Glucocorticoids and Water Balance: Implications for Hyponatremia Management and Pituitary Surgery
Glucocorticoids and Water Balance: Implications for Hyponatremia Management and Pituitary Surgery
Water balance is fundamental to all homeostasis. The hypothalamic pituitary adrenal (HPA) axis influences water balance th...
The Effects of Chronic Asprosin Administration on Sense of Smell and Sexual Behavior in Female Rats
The Effects of Chronic Asprosin Administration on Sense of Smell and Sexual Behavior in Female Rats
Introduction Asprosin is an adipokine released from white adipose tissue during fasting and acts through the olfactory rec...
Estradiol Enhances the Development of Addiction-Like Features in a Female Rat Model of Opioid Use Disorder
Estradiol Enhances the Development of Addiction-Like Features in a Female Rat Model of Opioid Use Disorder
<b><i>Introduction:</i></b> Women are more vulnerable than men in many aspects of opioid use disor...
MiRNA-383 AND MiRNA-384 SUPPRESS PROOPIOMELANOCORTIN GENE EXPRESSION IN THE HYPOTHALAMUS: EFFECTS OF EARLY LIFE ETHANOL EXPOSURE
MiRNA-383 AND MiRNA-384 SUPPRESS PROOPIOMELANOCORTIN GENE EXPRESSION IN THE HYPOTHALAMUS: EFFECTS OF EARLY LIFE ETHANOL EXPOSURE
Introduction: Early life ethanol exposure is known to program hypothalamic proopiomelanocortin (POMC) neurons to express a...
Second primary malignancies in patients with a neuroendocrine neoplasm in England
Second primary malignancies in patients with a neuroendocrine neoplasm in England
Introduction Patients with neuroendocrine neoplasms (NENs) may often develop other malignancies. This study aimed to ident...
Changes in corticotropin releasing factor receptor type 1, co-expression with tyrosine hydroxylase and oxytocin neurons, and anxiety-like behaviors across the postpartum period in mice
Changes in corticotropin releasing factor receptor type 1, co-expression with tyrosine hydroxylase and oxytocin neurons, and anxiety-like behaviors across the postpartum period in mice
Introduction: Corticotropin-releasing factor (CRF) and its primary receptor (CRFR1) are critical regulators of behavioral ...
Chromosome 18 loss of heterozygosity in small intestinal neuroendocrine tumours: Multi-omic and tumour composition analyses
Chromosome 18 loss of heterozygosity in small intestinal neuroendocrine tumours: Multi-omic and tumour composition analyses
Background: Small intestinal neuroendocrine tumours (siNETs) are rare neoplasms which present with low mutational burden a...
Identification of the immune subtypes for the prediction of metastasis in pancreatic neuroendocrine tumors
Identification of the immune subtypes for the prediction of metastasis in pancreatic neuroendocrine tumors
Introduction: Most patients with pancreatic neuroendocrine tumors (pNETs) present with unresectable or metastatic disease....
SILIBININ, AN HSP90 INHIBITOR, ON HUMAN ACTH-SECRETING ADENOMAS
SILIBININ, AN HSP90 INHIBITOR, ON HUMAN ACTH-SECRETING ADENOMAS
Introduction. The glucocorticoid receptor is pivotal to control corticotrophin (ACTH) secretion and its function is closel...
Endogenous sex hormones modulate the analgesic effect of tramadol in lean and high fat diet-induced obese Wistar rats: a preclinical molecular approach
Endogenous sex hormones modulate the analgesic effect of tramadol in lean and high fat diet-induced obese Wistar rats: a preclinical molecular approach
Introduction: Differences in pain thresholds may have implications in pain management, as they may account in part for the...
SIN3A defects associated with syndromic congenital hypogonadotropic hypogonadism: an overlap with Witteveen-Kolk syndrome
SIN3A defects associated with syndromic congenital hypogonadotropic hypogonadism: an overlap with Witteveen-Kolk syndrome
Introduction: Congenital hypogonadotropic hypogonadism (CHH) is a rare condition caused by GnRH deficiency. More than 40 g...
5-Iodotubercidin Inhibits the Growth of Insulinoma Cells by Inducing Apoptosis
5-Iodotubercidin Inhibits the Growth of Insulinoma Cells by Inducing Apoptosis
Background/Aims: 5-Iodotubercidin, a type of purine derivative, has attracted increasingly attention in tumor chemotherapy...
Author Index Vol. 113, No. 2, 2023
Author Index Vol. 113, No. 2, 2023
Neuroendocri...
Subject Index Vol. 113, No. 2, 2023
Subject Index Vol. 113, No. 2, 2023
Neuroendocri...
ERα stimulation rapidly modulates excitatory synapse properties in female rat nucleus accumbens core
ERα stimulation rapidly modulates excitatory synapse properties in female rat nucleus accumbens core
Introduction: The nucleus accumbens core (NAcc) is a sexually differentiated brain region that is modulated by steroid hor...
Diagnosis and Management of Idiopathic Hypothalamic Dysfunction: A Case Series and Systematic Review
Diagnosis and Management of Idiopathic Hypothalamic Dysfunction: A Case Series and Systematic Review
Introduction Idiopathic hypothalamic dysfunction (IHD) is a rare syndrome with heterogeneous clinical symptoms. This study...
Ultrastructural and molecular evidence of macroautophagy in functioning PitNETs and experimental pituitary tumors
Ultrastructural and molecular evidence of macroautophagy in functioning PitNETs and experimental pituitary tumors
Introduction: Macroautophagy is a lysosome-mediated degradation process that controls the quality of cytoplasmic component...
Paraventricular Nucleus of the Hypothalamus Oxytocin and Incubation of Heroin Seeking
Paraventricular Nucleus of the Hypothalamus Oxytocin and Incubation of Heroin Seeking
Introduction: There are numerous pharmacologic treatments for opioid use disorder (OUD), but none that directly target the...
Increased Lactobacillus Abundance Contributes to Stress Resilience in Mice Exposed to Chronic Social Defeat Stress
Increased Lactobacillus Abundance Contributes to Stress Resilience in Mice Exposed to Chronic Social Defeat Stress
<b><i>Introduction:</i></b> Accumulating evidence indicates that abnormalities in the composition ...
Genetic study in pheochromocytoma ¿is it possible to stratify the risk of hereditary pheochromocytoma?
Genetic study in pheochromocytoma ¿is it possible to stratify the risk of hereditary pheochromocytoma?
Introduction: It is estimated that 30-40% of patients with apparently sporadic pheochromocytomas (PHEOs) have an inherited...
Post-traumatic hypopituitarism - a neglected consequence of traumatic brain injury.
Post-traumatic hypopituitarism - a neglected consequence of traumatic brain injury.
Post-traumatic hypopituitarism (PTHP), described for the first time in 1918, used to be neglected and only considered a ra...
A PROSPECTIVE ANALYSIS OF THE METYRAPONE SHORT TEST USING TARGETED AND UNTARGETED METABOLOMICS
A PROSPECTIVE ANALYSIS OF THE METYRAPONE SHORT TEST USING TARGETED AND UNTARGETED METABOLOMICS
Introduction The present study aimed to prove the metyrapone short test in a day clinic to be suitable for examining the i...
Segmental Abnormalities of White Matter Microstructure in Primary Hypothyroidism Identified by Automated Fiber Quantification
Segmental Abnormalities of White Matter Microstructure in Primary Hypothyroidism Identified by Automated Fiber Quantification
Introduction: Hypothyroidism leads to impaired white matter (WM) integrity, associated with cognitive/neuropsychiatric dys...
Alterations of spontaneous cortical and subcortical activity in type 2 diabetes mellitus with and without depression
Alterations of spontaneous cortical and subcortical activity in type 2 diabetes mellitus with and without depression
Introduction: Type 2 diabetes mellitus (T2DM) patients with depression have a higher risk of complications and mortality t...
Potential of Ascorbic Acid supplements to Ameliorate the Deleterious Effects of Hyperuricemia on Albino Wistar Rats’ Hippocampus (Structural and Functional study)
Potential of Ascorbic Acid supplements to Ameliorate the Deleterious Effects of Hyperuricemia on Albino Wistar Rats’ Hippocampus (Structural and Functional study)
Introduction: Diet rich in purines may increase the serum level of uric acid causing hyperuricemia contributing learning a...
TSAb Modulates Microglia M1 Polarization via Activation of the TSHR-Mediated NF-κB Signaling Pathway
TSAb Modulates Microglia M1 Polarization via Activation of the TSHR-Mediated NF-κB Signaling Pathway
<b><i>Introduction:</i></b> Thyrotropin receptor-stimulating antibody (TSAb) is a pathogenic antib...
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