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Prodrug-based combinational nanomedicine remodels lipid metabolism for reinforced ferroptosis and immune activation
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RNA splicing: novel star in pulmonary diseases with a treatment perspective
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Modified probiotics and the related combinatorial therapeutics
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VenusMutHub: A systematic evaluation of protein mutation effect predictors on small-scale experimental data
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A chemotherapy nano-booster unlocks wider therapeutic window for prostate cancer treatment
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Phenotypic plasticity and secretory heterogeneity in subpopulations derived from single cancer cell
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Mechanism of Alzheimer’s disease treatment by sound and light stimulation
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SMAD4 depletion enhances NHEJ by regulating BRCA1 expression through ARIH1 in pancreatic cancer
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A simple widely applicable hairy root transformation method for gene function studies in medicinal plants
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Precise nanoscale fabrication technologies, the “last mile” of medicinal development
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CDH17-targeting CAR-NK cells synergize with CD47 blockade for potent suppression of gastrointestinal cancers
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Inhaled non-viral delivery systems for RNA therapeutics
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Commentary: Mammokine directs beige adipocytes to reserve energy for milk production in breast
Commentary: Mammokine directs beige adipocytes to reserve energy for milk production in breast
Available online 4 December 2023Author links open overlay panel, KeywordsbeigeBreastEpitheliail cellsscRNA-seqThermogenesi...
Design and discovery of a highly potent ultralong-acting GLP-1 and glucagon co-agonist for attenuating renal fibrosis
Design and discovery of a highly potent ultralong-acting GLP-1 and glucagon co-agonist for attenuating renal fibrosis
Available online 18 November 2023Author links open overlay panel, , , , , , , , , , , , , , , , AbstractThe role of co-ago...
In situ autophagy regulation in synergy with phototherapy for breast cancer treatment
In situ autophagy regulation in synergy with phototherapy for breast cancer treatment
AutophagyTumor phototherapySynergistic sensitizationHCQTRANSFERRINDisulfide bond reconstructionGSHBiomimetic mineralized n...
Late-stage modification of bioactive compounds: Improving druggability through efficient molecular editing
Late-stage modification of bioactive compounds: Improving druggability through efficient molecular editing
Available online 18 November 2023Author links open overlay panel, , , , , , AbstractSynthetic chemistry plays an indispens...
The emerging tumor microbe microenvironment: From delineation to multidisciplinary approach-based interventions
The emerging tumor microbe microenvironment: From delineation to multidisciplinary approach-based interventions
Intratumoral microbiota has become research hotspots, and emerges as a non-negligent new component of tumor microenvironme...
Phase separation of Nur77 mediates XS561-induced apoptosis by promoting the formation of Nur77/Bcl-2 condensates
Phase separation of Nur77 mediates XS561-induced apoptosis by promoting the formation of Nur77/Bcl-2 condensates
Available online 17 November 2023Author links open overlay panel, , , , , , , , , , , AbstractThe orphan nuclear receptor ...