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Deciphering the pharmacodynamic characteristics of acupuncture and neuromodulation therapies: A novel perspective from organoid platforms
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Research progress and prospect on the mechanisms of non-invasive neuromodulation therapy and acupuncture in treating cognitive impairment after traumatic brain injury
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Valproic acid: Mechanistic insights into neuronal actions, epigenetic modulation, and clinical risk
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Personalizing nutrition therapy in inflammatory bowel disease: Practical applications and review of the latest studies
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Orchestrating mitochondrial catastrophe: Mechanistic insights and therapeutic frontiers of cuproptosis in precision pharmacology
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Riluzole in neuroinflammation and neurodegeneration: Mechanistic insights and experimental validation
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Chrono-Immunotherapy in Precision Oncology: Circadian Control of the Tumor Microenvironment and Time-of-Day Optimization of Immune Checkpoint Blockade
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Methotrexate: Integrating Molecular Pharmacology, Systems Toxicology, and Precision Rescue Strategies
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Targeting the Ischemic Cascade: Review on Approved and Investigational Stroke Therapies
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Acupuncture and non-invasive neuromodulation–induced neuro-endocrine-immune changes associated with the amelioration of depression-like behaviors: A systematic review of animal studies
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
The neuro-metabolic epidemic and the CB1R paradox
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State-dependent neurotensin modulation in the brain: From network dynamics to pharmacological opportunity
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Alopecia areata: Mechanisms, targeted therapies, and translational challenges
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Systems pharmacology approaches to modeling immune training and tolerance
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Angiotensin II type 2 receptor signalling as a pain target: Bench, bedside and back-translation
Angiotensin II type 2 receptor signalling as a pain target: Bench, bedside and back-translation
Volume 73, December 2023, 102415Author links open overlay panel, , Highlights•Preclinical to clinical translation for nove...
Interventional functional diagnostics in gastrointestinal endoscopy: Combining diagnostic and therapeutic tools in the endoscopy suite with the functional lumen imaging probe
Interventional functional diagnostics in gastrointestinal endoscopy: Combining diagnostic and therapeutic tools in the endoscopy suite with the functional lumen imaging probe
Volume 73, December 2023, 102414Author links open overlay panel, , AbstractWith technical progress of gastrointestinal fun...
The role of Pannexin-1 channels, ATP, and purinergic receptors in the pathogenesis of HIV and SARS-CoV-2
The role of Pannexin-1 channels, ATP, and purinergic receptors in the pathogenesis of HIV and SARS-CoV-2
Pathogens, including viruses, have evolved to use host-encoded proteins to infect, replicate, and persist in the host [1]....
Pharmacologic treatment of gastroparesis: What is (still) on the horizon?
Pharmacologic treatment of gastroparesis: What is (still) on the horizon?
Volume 72, October 2023, 102395Author links open overlay panel, AbstractGastroparesis is a neuromuscular disorder of the u...
Discerning conformational dynamics and binding kinetics of GPCRs by 19F NMR
Discerning conformational dynamics and binding kinetics of GPCRs by 19F NMR
Available online 21 August 2023, 102377Author links open overlay panel, Abstract19F NMR provides a way of monitoring confo...
Illuminating GPCR signaling mechanisms by NMR spectroscopy with stable-isotope labeled receptors
Illuminating GPCR signaling mechanisms by NMR spectroscopy with stable-isotope labeled receptors
G protein-coupled receptors (GPCRs) are sensory integral membrane proteins that recognize an enormous range of extracellul...
Spinal and bulbar muscular atrophy: From molecular pathogenesis to pharmacological intervention targeting skeletal muscle
SBMA is caused by the expansion of a CAG/glutamine (polyQ) tract in the androgen receptor (AR) gene [1]. The glutamine tra...
Adenosine signaling as target in cardiovascular pharmacology
Cardiovascular diseases (CVDs) are the prominent cause of death globally, taking an estimated 17.9 million lives each year...
Targeting cAMP signaling compartments in iPSC-derived models of cardiovascular disease
Cardiovascular diseases (CVD) are diverse. They include amongst others ischemic heart disease, heart failure, many other h...
Spatiotemporal GPCR signaling illuminated by genetically encoded fluorescent biosensors
G protein-coupled receptors (GPCRs) form the largest class of cell membrane receptors and belong to the most important dru...
Central and peripheral mechanisms involved in the control of GnRH neuronal function by metabolic factors
Volume 71, August 2023, 102382Author links open overlay panel, , , AbstractGonadotropin-releasing hormone (GnRH) neurons a...
Corrigendum to “Antihypertensive effect of soybean bioactive peptides: A review” [Curr Opin Pharmacol (62) (2022) 74–81]
Volume 71, August 2023, 102383Author links open overlay panelTingna Li 1 a, Xiaorui Zhang 1 a, Yuanyuan Ren 1, Yijia Zeng ...
Highlighting vulnerabilities in the alternative lengthening of telomeres pathway
Human chromosomes end in telomeres, 5–15 kilobases of double-stranded (TTAGGG)n repeats that culminate in a 3′ single-stra...
Targeting DNA damage repair precision medicine strategies in cancer
Volume 70, June 2023, 102381Author links open overlay panel, , , , , , AbstractDNA repair targeted therapeutics is a promi...
Extracellular adenosine signaling in bone health and disease
Bone is a dynamic tissue which continuously undergoes remodeling primarily through osteoblast-mediated bone formation and ...
NMR applications to GPCR recognition by peptide ligands
G-protein coupled receptors (GPCR) are the largest superfamily of membrane proteins with more than 800 members that transd...
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