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Long-term effects of a COMPASS program on the caregiving journey: 1-year follow-up in a randomized controlled trial
Long-term effects of a COMPASS program on the caregiving journey: 1-year follow-up in a randomized controlled trial
Introduction: The number of older adults requiring long-term care (LTC) is increasing rapidly worldwide. The primary famil...
Blood Biomarkers for Healthy Aging
Blood Biomarkers for Healthy Aging
Measuring the abundance of biological molecules and their chemical modifications in blood and tissues has been the corners...
Brain Structural Correlates of Obstacle Negotiation in Mild Cognitive Impairment: Results from The Gait and Brain Study
Brain Structural Correlates of Obstacle Negotiation in Mild Cognitive Impairment: Results from The Gait and Brain Study
Introduction- Mild Cognitive Impairment (MCI) affects obstacle negotiation capabilities, potentially increasing the risk ...
The role of brain integrity in the association between occupational complexity and cognitive performance in subjects with increased risk of dementia
The role of brain integrity in the association between occupational complexity and cognitive performance in subjects with increased risk of dementia
Introduction: Mechanisms underlying the positive association between occupational mental demands and late-life cognition a...
Leisure Activities, Genetic Risk, and Frailty: Evidence from the Chinese Adults Aged 80 Years or Older
Leisure Activities, Genetic Risk, and Frailty: Evidence from the Chinese Adults Aged 80 Years or Older
Introduction: About half of adults aged ≥ 80 years suffer from frailty. Exercise is considered effective in preventing fra...
Aging with HIV: Working to Ensure Equity and Inclusion
Aging with HIV: Working to Ensure Equity and Inclusion
Due to effective anti-retroviral therapy (ART), the people with HIV are aging, and this is observed globally wherever ART ...
Caregiver Involvement and Concerns with Care of Residents of Assisted Living Before and During the COVID-19 Pandemic
Caregiver Involvement and Concerns with Care of Residents of Assisted Living Before and During the COVID-19 Pandemic
Introduction Family/friend caregivers play an essential role in promoting the physical and mental health of older adults i...
Prevalence and Risk Score for Hypertonic Dehydration Among Community-Dwelling Older Adults: an Analysis of the Bangkok Falls Study
Prevalence and Risk Score for Hypertonic Dehydration Among Community-Dwelling Older Adults: an Analysis of the Bangkok Falls Study
Introduction: Dehydration is associated with morbidity, and many factors affect dehydration in older adults including age ...
Suitability of Goal Attainment Scaling in Older Adult Populations with Neurodegenerative Disease Experiencing Cognitive Impairment: A Systematic Review and Meta-Analysis
Suitability of Goal Attainment Scaling in Older Adult Populations with Neurodegenerative Disease Experiencing Cognitive Impairment: A Systematic Review and Meta-Analysis
Introduction: Identifying responsive outcome measures for assessing functional change related to cognition, communication,...
Depression trajectories, genetic risk, and cognitive performance in older adults: multilevel model with a 10-year longitudinal cohort
Depression trajectories, genetic risk, and cognitive performance in older adults: multilevel model with a 10-year longitudinal cohort
Background: Cognitive performance in older ages is strongly affected by individuals’ genetic predispositions. We investiga...
Parkinson's Disease as a Risk Factor for Prostate Adenocarcinoma: a Molecular Point of View
Parkinson's Disease as a Risk Factor for Prostate Adenocarcinoma: a Molecular Point of View
Introduction: Cancer and neurodegeneration are two major leading causes of morbidity and death worldwide. Neurodegene...
Comparing the Effects of Two Perturbation-based Balance Training Paradigms in Fall-prone Older Adults: A Randomized Controlled Trial
Comparing the Effects of Two Perturbation-based Balance Training Paradigms in Fall-prone Older Adults: A Randomized Controlled Trial
Introduction There is increasing evidence that perturbation-based balance training (PBT) is highly effective in preventing...
Life Course Education, Health, and Ageing Well: A Short Inter-Academic Report
Life Course Education, Health, and Ageing Well: A Short Inter-Academic Report
After the first wave of the COVID-19 pandemic, during which the severity of the disease in certain countries was attribute...
The Role of Social Variables and Lifestyle Behaviors
The Role of Social Variables and Lifestyle Behaviors
<b><i>Introduction:</i></b> While some condition clusters represent the chance co-occurrence of co...
Activation of the Vascular Smooth Muscle GLP-1/NCX1 Pathway Regulates Cytoplasmic Ca2+ Homeostasis and Improves Blood Pressure Variability in Hypertension
Activation of the Vascular Smooth Muscle GLP-1/NCX1 Pathway Regulates Cytoplasmic Ca2+ Homeostasis and Improves Blood Pressure Variability in Hypertension
<b><i>Background:</i></b> Hypertension is the most common cardiovascular disease, and its main har...
Socially assistive robots for people living with dementia in long-term facilities: A systematic review and meta-analysis of randomized controlled trials
Socially assistive robots for people living with dementia in long-term facilities: A systematic review and meta-analysis of randomized controlled trials
Background and Objective: The purpose of our study was to explore the immediate and long-term effects of socially assistiv...
Effect of Youthful Blood Environment and Its Key Stem Cell Factor on Renal Interstitial Fibrosis in Elderly Mice
Effect of Youthful Blood Environment and Its Key Stem Cell Factor on Renal Interstitial Fibrosis in Elderly Mice
<b><i>Introduction:</i></b> Youthful blood environment was shown to decelerate the aging process o...
Life Course education, health, and aging well: A short inter-academic report
Life Course education, health, and aging well: A short inter-academic report
After the first wave of the COVID 19 pandemic, the severity of the disease in certain countries was attributed to a lack o...
Multimorbidity and functional disability among older adults - the role of inflammation and glycemic status: An Observational Longitudinal Study
Multimorbidity and functional disability among older adults - the role of inflammation and glycemic status: An Observational Longitudinal Study
Introduction: Specific multimorbidity combinations, in particular those including arthritis, stroke, and cognitive impairm...
Coping Patterns in Advanced Old Age: Findings from the Fordham Centenarian Study
Coping Patterns in Advanced Old Age: Findings from the Fordham Centenarian Study
Introduction. Research on coping in advanced old age is scarce. In the present study, we explored coping patterns in near-...
Covid-19 as an Independent Risk Factor for Weight Loss in Older Adults living in Nursing Homes
Covid-19 as an Independent Risk Factor for Weight Loss in Older Adults living in Nursing Homes
Introduction In nursing homes, where residents are at elevated risk for malnutrition, the specific additive effect of the ...
Supporting resilience of older adults with cognitive decline requires a multi-level system approach
Supporting resilience of older adults with cognitive decline requires a multi-level system approach
The concept of resilience, i.e., the capacity of a system to bounce back after a stressor, is gaining interest across many...
Multimorbidity patterns in older adults: the role of social variables and lifestyle behaviors
Multimorbidity patterns in older adults: the role of social variables and lifestyle behaviors
Introduction: While some conditions clusters represent the chance co-occurrence of common individual conditions, others ma...
The effect of social isolation on sarcopenia: a longitudinal study among the middle-aged and older population in China
The effect of social isolation on sarcopenia: a longitudinal study among the middle-aged and older population in China
Introduction: Although social isolation is associated with premature death and somatic and mental diseases, evidence of it...
Effect of youthful blood environment and its key factor SCF on renal interstitial fibrosis in elderly mice
Effect of youthful blood environment and its key factor SCF on renal interstitial fibrosis in elderly mice
Introduction: Youthful blood environment was shown to decelerate the aging process of kidney and to attenuate senile renal...
Probable Sarcopenia, Obesity, and Risk of All-Cause Mortality: A Pooled Analysis of 4,612 Participants
Probable Sarcopenia, Obesity, and Risk of All-Cause Mortality: A Pooled Analysis of 4,612 Participants
<b><i>Introduction:</i></b> Conflicting evidence exists concerning whether having sarcopenic obesi...
Role of NADPH Oxidases in Renal Aging
Role of NADPH Oxidases in Renal Aging
Introduction: Aging of the kidney is associated with complex molecular, histological, and functional changes. Although the...
Occurrence, characteristics and outcome of hypoxic liver injury among patients aged ≥ 90 years admitted to the intensive care unit – a retrospective cohort study
Occurrence, characteristics and outcome of hypoxic liver injury among patients aged ≥ 90 years admitted to the intensive care unit – a retrospective cohort study
Introduction: Hypoxic liver injury (HLI) is a frequent and life-threatening complication occurring in up to 10 % of critic...
Up-regulation of FGF7 induced Intra-vesical Prostatic Protrusion of Benign Prostatic Hyperplasia via the ERK1/2 signaling pathway
Up-regulation of FGF7 induced Intra-vesical Prostatic Protrusion of Benign Prostatic Hyperplasia via the ERK1/2 signaling pathway
Introduction: Intra-vesical Prostatic Protrusion (IPP) has been reported to be associated with bladder outlet obstruction ...
Acute sarcopenia
Acute sarcopenia
Sarcopenia is currently understood as an organ insufficiency. However, the distinction of acute and chronic sarcopenia as ...
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