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Long-run real-time PCR analysis of repetitive nuclear elements as a novel tool for DNA damage quantification in single cells: an approach validated on mouse oocytes and fibroblasts
Long-run real-time PCR analysis of repetitive nuclear elements as a novel tool for DNA damage quantification in single cells: an approach validated on mouse oocytes and fibroblasts
Since DNA damage is of great importance in various biological processes, its rate is frequently assessed both in research ...
Chloroplast genome of Justicia procumbens: genomic features, comparative analysis, and phylogenetic relationships among Justicieae species
Chloroplast genome of Justicia procumbens: genomic features, comparative analysis, and phylogenetic relationships among Justicieae species
Justicia procumbens L. is a traditional medicinal plant that is widely distributed in China. However, little is known abou...
Bioinformatics to analyze the differentially expressed genes in different degrees of Alzheimer’s disease and their roles in progress of the disease
Bioinformatics to analyze the differentially expressed genes in different degrees of Alzheimer’s disease and their roles in progress of the disease
Employing bioinformatics approaches, this investigation pinpointed pivotal differentially expressed genes (DEGs) across th...
Assessing cytotoxicity and endoplasmic reticulum stress in human blood–brain barrier cells due to silver and copper oxide nanoparticles
Assessing cytotoxicity and endoplasmic reticulum stress in human blood–brain barrier cells due to silver and copper oxide nanoparticles
In recent years, it has been generally accepted that metal-based nanoparticles (NPs) may induce stress in the endoplasmic ...
Peptidylprolyl isomerase D circular RNA sensitizes breast cancer to trastuzumab through remodeling HER2 N4-acetylcytidine modification
Peptidylprolyl isomerase D circular RNA sensitizes breast cancer to trastuzumab through remodeling HER2 N4-acetylcytidine modification
Human epidermal growth factor receptor 2 (HER2) overexpression and activation are crucial for trastuzumab resistance in HE...
Transcriptome meta-analysis-based identification of hub transcription factors and RNA-binding proteins potentially orchestrating gene regulatory cascades and crosstalk in response to abiotic stresses in Arabidopsis thaliana
Transcriptome meta-analysis-based identification of hub transcription factors and RNA-binding proteins potentially orchestrating gene regulatory cascades and crosstalk in response to abiotic stresses in Arabidopsis thaliana
Deteriorating climatic conditions and increasing human population necessitate the development of robust plant varieties re...
The role of multidisciplinary diagnostic and therapeutic model of care in Lamb-Shaffer syndrome - case report
The role of multidisciplinary diagnostic and therapeutic model of care in Lamb-Shaffer syndrome - case report
This case study illustrates a multidisciplinary diagnostic and therapeutic model of care for a 7-year-old male with Lamb&#...
Featured lncRNA-based signature for discriminating prognosis and progression of hepatocellular carcinoma
Featured lncRNA-based signature for discriminating prognosis and progression of hepatocellular carcinoma
Long non-coding RNAs (lncRNAs) have been implicated in carcinogenesis and progression of hepatocellular carcinoma (HCC). T...
Diallel analysis of common bean (Phaseolus vulgaris L.) genotypes for seed dietary fibre, carbohydrate, calcium and phosphorus contents
Diallel analysis of common bean (Phaseolus vulgaris L.) genotypes for seed dietary fibre, carbohydrate, calcium and phosphorus contents
Genetic information of bean seed traits can be an immense help to the breeder in selection of suitable genotypes and the a...
Triticale field phenotyping using RGB camera for ear counting and yield estimation
Triticale field phenotyping using RGB camera for ear counting and yield estimation
Triticale (X Triticosecale Wittmack), a wheat-rye small grain crop hybrid, combines wheat and rye attributes in one hexapl...
Uncovering the role of aquaporin and chromobox family members as potential biomarkers in head and neck squamous cell carcinoma via integrative multiomics and in silico approach
Uncovering the role of aquaporin and chromobox family members as potential biomarkers in head and neck squamous cell carcinoma via integrative multiomics and in silico approach
Head and neck squamous cell carcinoma (HNSC) is a diverse group of tumors arising from oral cavity, oropharynx, larynx, an...
Genomic Profiling Reveals Immune-Related Gene Differences in Lung Cancer Patients Stratified by PD1/PDL1 Expression: Implications for Immunotherapy Efficacy
Genomic Profiling Reveals Immune-Related Gene Differences in Lung Cancer Patients Stratified by PD1/PDL1 Expression: Implications for Immunotherapy Efficacy
Lung cancer remains a leading cause of global cancer-related mortality, and the exploration of innovative therapeutic appr...
A case of non-mosaic X trisomy (65,XXX) in a Thoroughbred mare confirmed by cytogenetic and molecular analysis
A case of non-mosaic X trisomy (65,XXX) in a Thoroughbred mare confirmed by cytogenetic and molecular analysis
A 9-year-old Thoroughbred mare with normal external genitalia and regular oestrus symptoms was gynecologically examined pr...
Enumeration of olive derived lignan, pinoresinol for activity against recent Omicron variant spike protein for structure-based drug design, DFT, molecular dynamics simulations, and MMGBSA studies
Enumeration of olive derived lignan, pinoresinol for activity against recent Omicron variant spike protein for structure-based drug design, DFT, molecular dynamics simulations, and MMGBSA studies
The coronavirus disease 2019 (COVID-19) was first found in Wuhan, China, in December 2019. Because the virus spreads quick...
Convergent evolution of allele-specific gene expression that leads to non-small cell lung cancer in different human populations
Convergent evolution of allele-specific gene expression that leads to non-small cell lung cancer in different human populations
Phenotypical innovations during evolution are caused by novel mutations, which are usually heterozygous at the beginning. ...
In vitro evaluation of biofilm phenotypic and genotypic characteristics among clinical isolates of Pseudomonas aeruginosa in Hamadan, West of Iran
In vitro evaluation of biofilm phenotypic and genotypic characteristics among clinical isolates of Pseudomonas aeruginosa in Hamadan, West of Iran
Due to high antimicrobial resistance and biofilm-forming ability, Pseudomonas aeruginosa is one of the seriously life-thre...
High expression of ACKR1 predicts a good prognosis and suppresses sarcoma cell progression via regulating the tumor immune microenvironment
High expression of ACKR1 predicts a good prognosis and suppresses sarcoma cell progression via regulating the tumor immune microenvironment
Sarcoma is a malignant tumor originating from mesenchymal tissue with a poor prognosis. Atypical chemokine receptor 1 (ACK...
Molecular complexity of diffuse large B-cell lymphoma: a molecular perspective and therapeutic implications
Molecular complexity of diffuse large B-cell lymphoma: a molecular perspective and therapeutic implications
Diffuse large B-cell lymphoma (DLBCL) stands as a formidable challenge in the landscape of non-Hodgkin’s lymphomas. ...
Correction to: Combining MTI‑31 with RAD001 inhibits tumor growth and invasion of kidney cancer by activating autophagy
Correction to: Combining MTI‑31 with RAD001 inhibits tumor growth and invasion of kidney cancer by activating autophagy
Huashan Hospital, Fudan University, 12 Middle Urumqi Road, Shanghai, 200040, ChinaWenye Zhang, Chen Yang, Lujia Zou, Yiwen...
Complex effects of the exo-xis region of the Shiga toxin-converting bacteriophage Φ24B genome on the phage development and the Escherichia coli host physiology
Complex effects of the exo-xis region of the Shiga toxin-converting bacteriophage Φ24B genome on the phage development and the Escherichia coli host physiology
Lambdoid bacteriophages are excellent models in studies on molecular aspects of virus-host interactions. However, some of ...
Combining MTI-31 with RAD001 inhibits tumor growth and invasion of kidney cancer by activating autophagy
Combining MTI-31 with RAD001 inhibits tumor growth and invasion of kidney cancer by activating autophagy
At most of the times, patients who are diagnosed with kidney cancer should be provided with systemic treatment as drug res...
The improvement of the in vitro plant regeneration in barley with the epigenetic modifier of histone acetylation, trichostatin A
The improvement of the in vitro plant regeneration in barley with the epigenetic modifier of histone acetylation, trichostatin A
Genotype-limited plant regeneration is one of the main obstacles to the broader use of genetic transformation in barley br...
Integrating ferroptosis-related genes (FRGs) and prognostic models to enhance UCEC outcome prediction and therapeutic insights
Integrating ferroptosis-related genes (FRGs) and prognostic models to enhance UCEC outcome prediction and therapeutic insights
Ferroptosis is closely associated with uterine corpus endometrial carcinoma (UCEC) development. This project aimed to iden...
The use of weighted multiple linear regression to estimate QTL × QTL × QTL interaction effects of winter wheat (Triticum aestivum L.) doubled-haploid lines
The use of weighted multiple linear regression to estimate QTL × QTL × QTL interaction effects of winter wheat (Triticum aestivum L.) doubled-haploid lines
Knowledge of the magnitude of gene effects and their interactions, their nature, and contribution to determining quantitat...
The forerunners and successful partnerships behind the BioNTech mRNA vaccine
The forerunners and successful partnerships behind the BioNTech mRNA vaccine
The discovery of nucleic acids stands as a paramount achievement in the history of scientific endeavors. By applying trans...
Identification of potential biomarkers for melanoma cancer (black tumor) using bioinformatics strategy: a study based on GEO and SRA datasets
Identification of potential biomarkers for melanoma cancer (black tumor) using bioinformatics strategy: a study based on GEO and SRA datasets
Melanoma, a highly invasive type of skin cancer that penetrates the entire dermis layer, is associated with increased mort...
The mitogenomes characterization of two Peltigera species (Peltigera elisabethae and Peltigera polydactylon) and comparative mitogenomic analyses of six Peltigera
The mitogenomes characterization of two Peltigera species (Peltigera elisabethae and Peltigera polydactylon) and comparative mitogenomic analyses of six Peltigera
In the present study, the mitochondrial genomes of Peltigera elisabethae and P. polydactylon were sequenced and assembled....
Genetic variants of MTHFR gene in relation to folic acid levels and bone mineral density in Polish patients with inflammatory bowel disease
Genetic variants of MTHFR gene in relation to folic acid levels and bone mineral density in Polish patients with inflammatory bowel disease
Lower bone mineral density (BMD) constitutes a common issue in inflammatory bowel disease (IBD). Studies often explore the...
Comprehensive bioinformatics analysis reveals the oncogenic role of FoxM1 and its impact on prognosis, immune microenvironment, and drug sensitivity in osteosarcoma
Comprehensive bioinformatics analysis reveals the oncogenic role of FoxM1 and its impact on prognosis, immune microenvironment, and drug sensitivity in osteosarcoma
Osteosarcoma, a highly malignant bone tumor primarily affecting adolescents, presents a significant challenge in cancer th...
SARS-CoV-2 continuously optimizes its codon usage to adapt to human lung environment
SARS-CoV-2 continuously optimizes its codon usage to adapt to human lung environment
Viruses need to utilize the resources from host cells to reproduce themselves. RNA translation rate, which is largely dete...
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