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Rewiring cancer: 3D genome determinants of cancer hallmarks
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Recipes and ingredients for deep learning models of 3D genome folding
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Principles of long-range gene regulation
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Fine-tuned programming of placenta trophoblast determines optimal maternal–fetal nutrient allocation
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Recent insights into the in vitro culture systems for mammalian embryos
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Insights and Interventions in Age-Associated Inflammation
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Decoding N6-methyladenosine’s dynamic role in stem cell fate and early embryo development: insights into RNA–chromatin interactions
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Modeling forebrain regional development and connectivity by human brain organoids
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Editorial overview: Regaining architecture and cell cross-talk upon regeneration
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Exploring the connection between RNA splicing and intellectual disability
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Bridging spatial and temporal scales of developmental gene regulation
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Genomic snowflakes: how the uniqueness of DNA folding allows us to smell the chemical universe
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Editorial overview: Peering into our history through a genetic lens: How advances in genetics are changing our understanding of human evolution
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R-loop homeostasis in genome dynamics, gene expression and development
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Multi-organelle-mediated mRNA localization in neurons and links to disease
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Modification of the RNA methylome in neurodevelopmental disorders
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Alternative splicing in addiction
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Pluripotent stem cell–derived mesenchymal stem cells for therapeutic applications, developmental study, and cancer research
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Interplay of transposable elements and ageing: epigenetic regulation and potential epitranscriptomic influence
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Totipotency or plenipotency: rethinking stem cell bipotentiality
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Topical section: embryonic models (2023) for Current Opinion in Genetics & Development
Topical section: embryonic models (2023) for Current Opinion in Genetics & Development
In recent years, modeling embryo development with stem cells has opened up new avenues in developmental biology. By recons...
Human blastoid as an in vitro model of human blastocysts
Human blastoid as an in vitro model of human blastocysts
Human development is a highly coordinated process, with any abnormalities during the early embryonic stages that can often...
‘Enhancing’ skeletal muscle and stem cells in three-dimensions: genome regulation of skeletal muscle in development and disease
‘Enhancing’ skeletal muscle and stem cells in three-dimensions: genome regulation of skeletal muscle in development and disease
Skeletal muscle (SkM) is one of the most plastic tissues in the human body with an amazing ability to adapt to imposed dem...
Modifying gastruloids to dissect mechanisms of tissue-specific induction
Modifying gastruloids to dissect mechanisms of tissue-specific induction
How functional organisms arise from a single cell is a fundamental question in biology with direct relevance to understand...
Somatic mutation burden in relation to aging and functional life span: implications for cellular reprogramming and rejuvenation
Somatic mutation burden in relation to aging and functional life span: implications for cellular reprogramming and rejuvenation
Our understanding of somatic mutations and their connection to the aging process has seen significant advancements over th...
‘Enhancing’ skeletal muscle and stem cells in three-dimensional: genome regulation of skeletal muscle in development and disease
‘Enhancing’ skeletal muscle and stem cells in three-dimensional: genome regulation of skeletal muscle in development and disease
Skeletal muscle (SkM) is one of the most plastic tissues in the human body with an amazing ability to adapt to imposed dem...
Editorial overview: Conflicts, conflicts everywhere
Editorial overview: Conflicts, conflicts everywhere
Harmit Malik obtained his Ph.D. from the Department of Biology at the University of Rochester (Rochester, NY) under the me...
Divergent outcomes of genetic conflict on the UV sex chromosomes of Marchantia polymorpha and Ceratodon purpureus
Divergent outcomes of genetic conflict on the UV sex chromosomes of Marchantia polymorpha and Ceratodon purpureus
Many eukaryotes have separate female and male individuals. In such species, one genome must implement two distinct develop...
Insights and applications of direct neuronal reprogramming
Insights and applications of direct neuronal reprogramming
Cell fate is determined through a coordinated activity of transcription factors (TFs) and chromatin-remodeling complexes t...
Overcoming muscle stem cell aging
Overcoming muscle stem cell aging
Volume 83, December 2023, 102127Author links open overlay panel, Reduced muscle strength and mass is one of the hallmarks ...
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