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SCI Abstract
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Identification of a New Compound (4-Fluoro-2-Trifluoromethyl Imidazole) Extracted From a New Halophilic Bacillus aquimaris Strain Persiangulf TA2 Isolated From the Northern Persian Gulf With Broad-Spectrum Antimicrobial Effect
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Molecular identification of Juglans regia endophyte LTL-G3, its antifungal potential and bioactive substances
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Enhancement of Essential Oil Production and Expression of Some Menthol Biosynthesis-Related Genes in Mentha piperita Using Cyanobacteria
Background: Mentha piperita L. is one of the most important aromatic crops and is cultivated worldwide for essential oils ...
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Green Synthesis of Polylactic acid/Fe3O4@β-Cyclodextrin Nanofibrous Nanocomposite Loaded with Ferulago Angulata Extract as a Novel Nano-biosorbent: Evaluation of Diazinon Removal and Antibacterial Activity
Background: Organophosphate pesticides are one of the most extensively applied insecticides in agriculture. These insectic...
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Gene Networks Analysis of Salmonella Typhimurium Reveals New Insights on Key Genes Involved in Response to Low Water Activity
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Research on Circular RNA Expression Profiles in the Photoaging Mouse Model
Background: Nude mouse has been widely used to study photoaging induced by long-term chronic UV exposure. Circular RNAs (c...
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CRISPR/Cas9-Induced Fam83h knock-out Leads to Impaired Wnt/β-Catenin Pathway and Altered Expression of Tooth Mineralization Genes in Mice
Background: Dental enamel formation is a complex process that is regulated by various genes. One such gene, Family With Se...
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Introns and their therapeutic applications in biomedical researches: A Review
Context: Although for a long time, it was thought that intervening sequences (introns) were junk DNA without any function,...
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A Comprehensive Review of the Key Characteristics of the Genus Mentha, Natural Compounds and Biotechnological Approaches for the Production of Secondary Metabolites
Context: The genus Mentha is one of the most aromatic and well-known members of the Lamiaceae family. A wide range of bioa...
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Optimization of Affinity Chromatography Based on Sepharose 4Bchitin for Rapid Purification of Urtica dioica Agglutinin
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The Effect of Collagen and Fibrin Hydrogels Encapsulated with Adipose Tissue Mesenchymal Stem Cell-Derived Exosomes for Treatment of Spinal Cord Injury in a Rat Model
Background: Mesenchymal stem cell (MSC) derived exosomes (MSC-DE) have been demonstrated to be potential candidates for th...
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SOX2 Overlapping Transcript (SOX2-OT) enhances the Lung cancer malignancy through interaction with miR-194-5p/SOX5 axis
Background: Lung cancer is one of the most common types of cancer and a leading cause of cancer-related deaths worldwide. ...
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Cloning, Prokaryotic Expression and Functional Characterization of nifH Gene from the Associative Nitrogen-fixing Bacteria Klebsiella variicola DX120E
Background: Biological nitrogen fixation (BNF) is a unique mechanism in which microorganisms utilize the nitrogenase enzym...
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MiRNA-145-5p restrains malignant behaviors of breast cancer cells via downregulating H2AFX expression
Background: Breast cancer is a prevalent tumor with high aggressiveness among female populations. MiRNA-145-5p plays an im...
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In vitro gluten degradation using recombinant Eurygaster integriceps prolyl endoprotease : Implications for Celiac Disease
Background: Celiac disease (CD) is a gluten-sensitive chronic autoimmune enteropathy. A strict life-long gluten-free diet ...
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Data-mining of Barley to identify salt stress hub genes, gene expression analysis, and recombinant plasmid construction
Background: Salinity is one of the major abiotic stresses that limit the production and yields of crops worldwide. Objecti...
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PPI Identification of immune-related biomarkers in esophageal cancer on the basis of gene co-expression network
Background: The mortality rate of esophageal cancer is on the continuous increase. Fortunately, with the development of im...
Iranian Journal Of Biotechnology
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Optimization of Affinity Chromatography Based on Sepharose 4B-chitin for Rapid Purification of Urtica dioica Agglutinin
Background: Today, numerous antimicrobial and anticancer properties have been reported for plant lectins due to their abil...
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Anti-inflammatory properties of extract of the hairy root of native Portulaca oleracea L. and its effect on some inflammatory genes expression in rat microglial cells
Background: Most herbs play significant roles in the treatment of various diseases. Because dopamine functions in the anti...
Iranian Journal Of Biotechnology
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Dexmedetomidine suppresses glutamate-stimulated neuronal injury via microRNA-433/Janus kinase 2/Signal transducer and activator of transcription 3 pathway
Objective: To explore the protective action and mechanism of dexmedetomidine (Dex) on HT22. Materials and Methods: Constru...
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The Effect of Collagen and Fibrin Hydrogels Encapsulated with Adipose Tissue Mesenchymal Stem Cell Derived Exosomes for Treatment of Spinal Cord Injury (SCI) In A Rat Animal Model
Background: Mesenchymal Stem Cell (MSC) Derived Exosomes (Mscs-DE) Have Been Demonstrated to Be Potential Candidates for T...
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Inhibition of NO Production in LPS-Stimulated Primary Rat Glial Cells by Gnidilatimonoein and Extract of Daphne mucronata
Background: In the CNS, glial cells are involved in neuroinflammation and neuropathic pain. The glial cells are activated ...
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Multi-Objective Optimization of Copper Bioleaching: Comparative Study of Pure and Co-Cultured Cultivation
Background: Bioleaching is a practical method to recover metals from low-grade mineral sulfides. The most frequent bacteri...
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Response Surface Methodology To Optimize The Expression Efficiency Of Recombinant Reteplase
Background: over expression of Reteplase enzyme has already been studies in the periplasmic space of Escherichia coli (E. ...
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Isolation, Identification, and Characterization of the Native Yeast Strains from Homemade Cheese to Assess their Eliminating Impact on the Aflatoxin B1 and M1 of the Simulated Gastrointestinal Fluid
Background: The occurrence of aflatoxins in food products is a silent threat to human health worldwide. A range of strateg...
Iranian Journal Of Biotechnology
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Preparation and Characterization of Crayfish (Astacus leptodactylus) Chitosan with Different Deacetylation Degrees
Background: In this study, chitosan with various deacetylation degrees was extracted from crayfish (Astacus leptodactylus)...
Iranian Journal Of Biotechnology
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Efficient CRISPR/Cas9-mediated BAX Gene Ablation In CHO Cells To Impair Apoptosis and Enhance Recombinant Protein Production
Background: Despite recent advances in recombinant biotherapeutics production using CHO cells, their productivity remains ...
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Pan-cancer analysis reveals SRC may link lipid metabolism and macrophages
Background: SRC is a member of the membrane-associated non-receptor protein tyrosine kinase superfamily. It has been repor...
Iranian Journal Of Biotechnology
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Inhibition of NO Production in LPS-Stimulated Primary Rat Glia Cells by Gnidilatimonoein and Extract of Daphne Mucronata
Background: Glia cells in the CNS play key roles in neuro-inflammation and neuropathic pain. They are activated upon vario...
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Evaluating and Validating Sunflower Reference Genes for Q-PCR Studies Under High Temperature Condition
Background: Q-PCR is the method of choice for PCR- based transcriptomics and validating microarray-based and RNA-seq resul...
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