SCI Abstract

search
+
How pathogens drive adipose tissue loss in the host
Weight loss is a hallmark of many infections, including those caused by bacteria, fungi and parasites. This loss is often ...
Immune evasion runs in the family: two surface protein families of Plasmodium falciparum–infected erythrocytes
Two protein families are found on the surfaces of erythrocytes infected with Plasmodium falciparum, a causative agent of d...
Moving beyond discovery science to a mechanistic understanding of human malaria
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2025 Elsevier B.V., its licensors, an...
The role of microbial succinate in the pathophysiology of inflammatory bowel disease: mechanisms and therapeutic potential
Inflammatory bowel disease (IBD) is a chronic, immune-mediated condition characterized by inflammation of the gastrointest...
Pathogen adaptation to lung metabolites
Upon invading mucosal tissues such as the lung, opportunistic pathogens must rapidly adapt to locally available carbon sou...
Long-chain fatty acids as nutrients for Gram-negative bacteria: stress, proliferation, and virulence
Fatty acids, carboxylic acids with a saturated or unsaturated aliphatic chain, are classified as short- (<6 carbons), m...
Dividing lines: compartmentalisation and division in Streptomyces
Bacteria display diverse strategies for cell division, exemplified by the multicellular life cycle of Streptomyces, a genu...
Organizing organelles: bacterial strategies for localizing intracellular compartments
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2025 Elsevier B.V., its licensors, an...
Cell cycle regulation in Escherichia coli: from governing principles, checkpoints, and control variables to molecular mechanisms
All cells share the basic challenge of integrating the various processes that ensure their faithful replication. In most b...
Immunometabolism shapes chronic Staphylococcus aureus infection: insights from biofilm infection models
Staphylococcus aureus is a commensal organism that colonizes the skin, nasal passages, and other body sites of approximate...
A solution to the postantibiotic era: phages as precision medicine
With the threat of a postantibiotic era looming, there is great interest in developing new therapeutics to take their plac...
The importance of persistence and dormancy in Trypanosoma cruzi infection and Chagas disease
T. cruzi is a kinetoplastid protozoan and the causative agent of Chagas disease. Despite the restriction of the insect-vec...
Skin models for studying vector-borne kinetoplastid infections
Kinetoplastid infections, caused by Leishmania and Trypanosoma species, pose significant global health challenges, disprop...
Encapsulins: catalysis inside a shell
Internal cellular organization is a defining feature of life, and encapsulins are an effective, protein-based method for p...
A tale of two nitrous oxide reductases: a cautionary perspective
Volume 86, August 2025, 102631Author links open overlay panel, , Highlights•N2O reductases, encoded by nosZ, are phylogene...
Specialized biopolymers: versatile tools for microbial resilience
Specialized biopolymers: versatile tools for microbial resilience
Biopolymers are a chemically diverse group of high-molecular-weight molecules composed of repeating building blocks, such ...
Multilayered regulation of amino acid metabolism in Escherichia coli
Multilayered regulation of amino acid metabolism in Escherichia coli
Escherichia coli primarily constitutes 0.1–5% of the mammalian gut microbiome and can also be found in the gut of birds, r...
Unlocking the potential of optogenetics in microbial applications
Unlocking the potential of optogenetics in microbial applications
Optogenetics is a powerful approach that enables researchers to use light to dynamically manipulate cellular behavior. Sin...
Nutritional control of bacterial DNA replication
Nutritional control of bacterial DNA replication
All cells must ensure precise regulation of DNA replication initiation in coordination with growth rate and in response to...
PhoU: a multifaceted regulator in microbial signaling and homeostasis
PhoU: a multifaceted regulator in microbial signaling and homeostasis
Inorganic phosphate (Pi) is one of the essential molecules required for many biological processes, including synthesis of ...
Matching the β-oxidation gene repertoire with the wide diversity of fatty acids
Matching the β-oxidation gene repertoire with the wide diversity of fatty acids
Bacteria can use fatty acids (FAs) from their environment as carbon and energy source. This catabolism is performed by the...
The multifaceted roles of Myb domain–containing proteins in apicomplexan parasites
The multifaceted roles of Myb domain–containing proteins in apicomplexan parasites
The phylum of apicomplexan parasites is a large and diverse clade of protists that is responsible for significant diseases...
Crosstalk between (p)ppGpp and other nucleotide second messengers
Crosstalk between (p)ppGpp and other nucleotide second messengers
The remarkable ability of bacteria to colonize diverse habitats relies on their efficient response to environmental change...
Environmental adaptation and diversification of bacterial two-component systems
Environmental adaptation and diversification of bacterial two-component systems
Two-component systems (TCSs) are highly conserved signaling mechanisms that allow cells to sense and respond to diverse in...
Innovative and potential treatments for fungal central nervous system infections
Innovative and potential treatments for fungal central nervous system infections
Central nervous system (CNS) infections are caused by diverse microorganisms, including viruses, bacteria, fungi, and para...
Cell cycle-regulated ApiAP2s and parasite development: the Toxoplasma paradigm
Cell cycle-regulated ApiAP2s and parasite development: the Toxoplasma paradigm
The cell division cycle of T. gondii is driven by cyclically expressed ApiAP2 transcription factors (AP2s) that promote ge...
Control of bacterial second messenger signaling and motility by heme-based direct oxygen-sensing proteins
Control of bacterial second messenger signaling and motility by heme-based direct oxygen-sensing proteins
Bacteria sense and respond to their environment, allowing them to maximize their survival and growth under changing condit...
Non-canonical food sources: bacterial metabolism of Maillard reaction products and its regulation
Non-canonical food sources: bacterial metabolism of Maillard reaction products and its regulation
We use cookies to help provide and enhance our service and tailor content and ads. By continuing you agree to the use of c...
Evolution and synthetic biology
Evolution and synthetic biology
Evolutionary observations have often served as an inspiration for biological design. Decoding of the central dogma of life...
Antibiotics from rare actinomycetes, beyond the genus Streptomyces
Antibiotics from rare actinomycetes, beyond the genus Streptomyces
Throughout the golden age of antibiotic discovery, Streptomyces have been unsurpassed for their ability to produce bioacti...
Load More
format_indent_increase