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Neuropsychiatric side effects of montelukast: time to change prescribing practice?
Neuropsychiatric side effects of montelukast: time to change prescribing practice?
Since 1998, montelukast has been licensed for the treatment of seasonal allergic rhinitis and asthma in people aged over 6...
Correction: Whats hot that the other lot got
Correction: Whats hot that the other lot got
Higginson J. What’s hot that the other lot got. Thorax 2015;70:1010.This Journal club article was originally published wit...
Cost-related nonadherence to medication among people with asthma in the United States: findings that reinforce the relevance of history and healthcare reform
Cost-related nonadherence to medication among people with asthma in the United States: findings that reinforce the relevance of history and healthcare reform
Asthma affects over 20 million (8%) of adults in the United States (US) each year.1 2 As with many chronic conditions, poo...
Beyond glycaemic control: reduced pneumonia and sepsis risk with GLP-1 RAs and SGLT2 inhibitors in patients with type 2 diabetes
Beyond glycaemic control: reduced pneumonia and sepsis risk with GLP-1 RAs and SGLT2 inhibitors in patients with type 2 diabetes
As of 2021, 537 million adults are living with diabetes, globally. This is expected to reach 800 million in 20 years.1 Pat...
Quantitative BAL: a suitable method for the assessment of epithelial lining fluid in alpha-1 antitrypsin deficiency?
Quantitative BAL: a suitable method for the assessment of epithelial lining fluid in alpha-1 antitrypsin deficiency?
Measurements on biological fluids form the mainstay of routine clinical investigations. Samples of blood, urine, etc are, ...
Cost-related non-adherence to medications among adults with asthma in the USA, 2011-2022
Cost-related non-adherence to medications among adults with asthma in the USA, 2011-2022
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYIntroductionAsthma is one of th...
Neuropsychiatric diagnoses after montelukast initiation in paediatric patients with asthma
Neuropsychiatric diagnoses after montelukast initiation in paediatric patients with asthma
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Comparative estimate of glucose-lowering therapies on risk of incident pneumonia and severe sepsis: an analysis of real-world cohort data
Comparative estimate of glucose-lowering therapies on risk of incident pneumonia and severe sepsis: an analysis of real-world cohort data
IntroductionDespite advances in the efficacy of, and access to, antibiotic therapies, pneumonia remains the most common gl...
Optimising bronchoalveolar lavage: lessons from alpha-1 antitrypsin deficiency
Optimising bronchoalveolar lavage: lessons from alpha-1 antitrypsin deficiency
WHAT IS ALREADY KNOWN ON THIS TOPICBronchoalveolar lavage (BAL) is essential in evaluating the biochemical efficacy of nov...
Community-based approaches to improve tuberculosis services: observations from preintervention and postintervention surveys in a high TB burden disadvantaged community in India
Community-based approaches to improve tuberculosis services: observations from preintervention and postintervention surveys in a high TB burden disadvantaged community in India
IntroductionIndia has the highest tuberculosis (TB) burden (26%) and accounts for 34% of the TB deaths in the world.1 The ...
Effect of nostril occlusion and mouth sealing in the measurement of sniff nasal inspiratory pressure
Effect of nostril occlusion and mouth sealing in the measurement of sniff nasal inspiratory pressure
BackgroundRespiratory muscle weakness is a common feature of neuromuscular conditions and can be predictive of outcome1 2;...
Atypical radiological manifestation of sarcoidosis presenting with an anterior mediastinal mass
Atypical radiological manifestation of sarcoidosis presenting with an anterior mediastinal mass
A 44-year-old woman presented with a persistent diffuse skin rash for 3 months, along with progressively worsening dyspnoe...
Pulmonary infection caused by Talaromyces amestolkiae
Pulmonary infection caused by Talaromyces amestolkiae
A 38-year-old woman was admitted for uterine fibroid surgery. A routine preoperative CT chest scan identified bilateral pa...
New management pathways for follow-up of CPAP-treated sleep apnoea patients including digital medicine and multimodal telemonitoring
New management pathways for follow-up of CPAP-treated sleep apnoea patients including digital medicine and multimodal telemonitoring
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Correction: Night shift work is associated with an increased risk of asthma
Correction: Night shift work is associated with an increased risk of asthma
Maidstone RJ, Turner J, Vetter C, et al. Night shift work is associated with an increased risk of asthma. Thorax 2021;76:5...
Novel electromagnetic navigation bronchoscopy system for the diagnosis of peripheral pulmonary nodules: a prospective, multicentre study
Novel electromagnetic navigation bronchoscopy system for the diagnosis of peripheral pulmonary nodules: a prospective, multicentre study
WHAT IS ALREADY KNOWN ON THIS TOPICElectromagnetic navigation bronchoscopy (ENB) has been shown to improve the diagnostic ...
Readmission following hospital admission for community-acquired pneumonia in England
Readmission following hospital admission for community-acquired pneumonia in England
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Moving mountains in community-acquired pneumonia: stone by stone we progress
Moving mountains in community-acquired pneumonia: stone by stone we progress
Community-acquired pneumonia (CAP) is a leading cause of hospitalisation with high inpatient mortality. Mortality and morb...
Increasing respiratory burden of prematurity: can we turn the tide?
Increasing respiratory burden of prematurity: can we turn the tide?
Despite many improvements in neonatal care, prematurity remains a significant cause of childhood mortality and morbidity, ...
Outcomes of systemic sclerosis associated interstitial lung disease patients with a persistent inflammatory phenotype based on serial CRP measurements
Outcomes of systemic sclerosis associated interstitial lung disease patients with a persistent inflammatory phenotype based on serial CRP measurements
Interstitial lung disease (ILD) is a serious complication of systemic sclerosis (SSc) with a variable clinical trajectory....
Recent trends in asthma diagnosis, preschool wheeze diagnosis and asthma exacerbations in English children and adolescents: a SABINA Jr study
Recent trends in asthma diagnosis, preschool wheeze diagnosis and asthma exacerbations in English children and adolescents: a SABINA Jr study
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSUsing routinely collected data from primary care practice in the UK...
Atopic and non-atopic effects of fish oil supplementation during pregnancy
Atopic and non-atopic effects of fish oil supplementation during pregnancy
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Phenotyping by persistent inflammation in systemic sclerosis associated interstitial lung disease: a EUSTAR database analysis
Phenotyping by persistent inflammation in systemic sclerosis associated interstitial lung disease: a EUSTAR database analysis
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Fragmentation of care between intensive and primary care settings and opportunities for improvement
Fragmentation of care between intensive and primary care settings and opportunities for improvement
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Early experience of a new national lung allocation scheme in the UK based on clinical urgency
Early experience of a new national lung allocation scheme in the UK based on clinical urgency
IntroductionIn the UK, there are five adult lung transplant centres. Until 2017, for the purpose of donor lung allocation,...
Donor lung allocation scheme: how can we measure success?
Donor lung allocation scheme: how can we measure success?
The National Health Service Blood and Transplant Cardiothoracic Advisory Group, in line with the principles of priority to...
Risk factors for poorer respiratory outcomes in adolescents and young adults born preterm
Risk factors for poorer respiratory outcomes in adolescents and young adults born preterm
WHAT IS ALREADY KNOWN ON THIS TOPICThe literature overwhelmingly reports (although largely by spirometry only) that those ...
Respiratory management and outcomes in high-risk preterm infants with development of a population outcome dashboard
Respiratory management and outcomes in high-risk preterm infants with development of a population outcome dashboard
IntroductionBronchopulmonary dysplasia (BPD) remains one of the most common and costly conditions affecting preterm infant...
Core outcome set for pulmonary rehabilitation of patients with COPD: results of a modified Delphi survey
Core outcome set for pulmonary rehabilitation of patients with COPD: results of a modified Delphi survey
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Lung function tracking in children with perinatally acquired HIV following early antiretroviral therapy initiation
Lung function tracking in children with perinatally acquired HIV following early antiretroviral therapy initiation
IntroductionHIV-associated lung disease has evolved with the introduction of vertical transmission prophylaxis and antiret...
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