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Novel Loss-of-function Variants of ZP3 Associated with Premature Ovarian Insufficiency
Novel Loss-of-function Variants of ZP3 Associated with Premature Ovarian Insufficiency
Premature ovarian insufficiency (POI) is one of the leading causes of female infertility. To date, the genetic etiology of...
The Role of Granulocyte Colony Stimulating Factor in Mitigating the Risk of Recurrent Miscarriages: A Comprehensive Review and Meta-Analysis
The Role of Granulocyte Colony Stimulating Factor in Mitigating the Risk of Recurrent Miscarriages: A Comprehensive Review and Meta-Analysis
Granulocyte colony-stimulating factor (G-CSF), a pivotal hematopoietic cytokine, has been noted for its potential to bolst...
Probiotics Combined with Metformin Improves Sperm Parameters in Obese Male Mice through Modulation of Intestinal Microbiota Equilibrium
Probiotics Combined with Metformin Improves Sperm Parameters in Obese Male Mice through Modulation of Intestinal Microbiota Equilibrium
The decline in sperm parameters among obese males has attracted significant scholarly interest. The intestinal microbiota ...
Association of Parity with Type 2 Diabetes Mellitus in Japan
Association of Parity with Type 2 Diabetes Mellitus in Japan
This study investigates the association between parity and type 2 diabetes mellitus (T2DM) in Japanese women, considering ...
Circ_0008440 Inhibits Proliferation and Promotes Apoptosis of Trophoblast Cells through the miR-194-5p/PFKFB2 Axis
Circ_0008440 Inhibits Proliferation and Promotes Apoptosis of Trophoblast Cells through the miR-194-5p/PFKFB2 Axis
Preeclampsia (PE), an idiopathic hypertensive disorder that arises during pregnancy, poses a serious threat to the health ...
Placental and Fetal Metabolic Reprogramming in Pregnancies with Intrauterine Growth Restriction
Placental and Fetal Metabolic Reprogramming in Pregnancies with Intrauterine Growth Restriction
The high-altitude hypoxia model demonstrates that insufficiently oxygenated placentas activate compensatory mechanisms to ...
The Microbiome Landscape of Adenomyosis: A Systematic Review
The Microbiome Landscape of Adenomyosis: A Systematic Review
Alterations in the microbiome composition have been identified in common gynecologic pathologies such as endometriosis car...
Mid-Pregnancy Placental Transcriptome in a Model of Placental Insufficiency with and without Novel Intervention
Mid-Pregnancy Placental Transcriptome in a Model of Placental Insufficiency with and without Novel Intervention
Fetal growth restriction (FGR) affects between 5-10% of all live births. Placental insufficiency is a leading cause of FGR...
A 12-h Difference in Exogenous Progesterone Initiation Does Not Have an Impact on Ongoing Pregnancy Rates in Artificial Cycles, as Long as Luteal Phase Support Starts Five Days Before Blastocyst Transfer
A 12-h Difference in Exogenous Progesterone Initiation Does Not Have an Impact on Ongoing Pregnancy Rates in Artificial Cycles, as Long as Luteal Phase Support Starts Five Days Before Blastocyst Transfer
To elucidate if morning or evening start of exogenous progesterone (P4) five days before blastocyst embryo transfer (ET) i...
Evaluation of the In Vivo Efficacy of the JAK Inhibitor AZD1480 in Uterine Leiomyomas Using a Patient-derived Xenograft Murine Model
Evaluation of the In Vivo Efficacy of the JAK Inhibitor AZD1480 in Uterine Leiomyomas Using a Patient-derived Xenograft Murine Model
Uterine leiomyomas are common noncancerous hormonally-dependent neoplasms comprised of uterine smooth-muscle cells and fib...
Reclassifying a Novel POMT1 Variant by Integrating Functional Analysis and Bioinformatics: Implications for Preimplantation Genetic Testing
Reclassifying a Novel POMT1 Variant by Integrating Functional Analysis and Bioinformatics: Implications for Preimplantation Genetic Testing
The advancement of next-generation sequencing has spurred the growing adoption of whole-exome sequencing (WES) for genetic...
Research Hotspots and Thematic Trends in the Management of Preeclampsia: A Bibliometric Analysis from 2000 to 2022
Research Hotspots and Thematic Trends in the Management of Preeclampsia: A Bibliometric Analysis from 2000 to 2022
Preeclampsia (PE) is one of the serious complications of pregnancy, and the management of PE remains an important problem ...
Effect of SGLT2 Inhibitors on Improving Glucolipid Metabolism and Reproductive Hormone Status in Overweight/Obese Women with PCOS: A Systematic Review and Meta-Analysis
Effect of SGLT2 Inhibitors on Improving Glucolipid Metabolism and Reproductive Hormone Status in Overweight/Obese Women with PCOS: A Systematic Review and Meta-Analysis
Obesity, insulin resistance, and hyperandrogenemia are commonly seen in women with polycystic ovary syndrome (PCOS), and t...
Visual Analogue Scale Cut-off Point of Seven Represents Poor Quality of Life in Patients with Endometriosis
Visual Analogue Scale Cut-off Point of Seven Represents Poor Quality of Life in Patients with Endometriosis
Establishing objective criteria to assess endometriosis symptoms is crucial in defining therapeutic strategies. The visual...
Uroplakin 1a Interacts with Regucalcin and Proteasome Subunit Beta 1
Uroplakin 1a Interacts with Regucalcin and Proteasome Subunit Beta 1
Uroplakins (UPKs) are specialized proteins that plan an important role in protecting the epithelium of the bladder from to...
Adult-Onset Still’s Disease in Pregnancy: Lessons Learned and an Approach to Subsequent Pregnancies
Adult-Onset Still’s Disease in Pregnancy: Lessons Learned and an Approach to Subsequent Pregnancies
Adult-onset Still’s disease (AOSD) is a rare autoinflammatory disorder with potential for life-threatening complicat...
Prenatal Diagnosis of Diastematomyelia: a Case Report and Literature Review
Prenatal Diagnosis of Diastematomyelia: a Case Report and Literature Review
Diastematomyelia is a type of closed spinal dysraphism in which there is splitting of the spinal cord. It is a rare entity...
Navigation of Knowledge: the Impact of COVID-19 on Pregnancy-a Bibliometric Analysis
Navigation of Knowledge: the Impact of COVID-19 on Pregnancy-a Bibliometric Analysis
Since the outbreak of COVID-19, countries around the world have faced huge economic and social burdens. SARS-COV-2 may exi...
Interleukin-6 Concentration in Single-Embryo Medium Is Associated with Blastocyst Formation
Interleukin-6 Concentration in Single-Embryo Medium Is Associated with Blastocyst Formation
IL-6 plays an important role in oogenesis in humans. However, at the preimplantation stage, IL-6 production and the role i...
Unraveling the Clinical Relevance of Ferroptosis-Related Genes in Human Ovarian Aging
Unraveling the Clinical Relevance of Ferroptosis-Related Genes in Human Ovarian Aging
Ferroptosis, a recently discovered form of cell death, has been implicated in various diseases. However, the genetic relat...
Comparison of Letrozole and Clomiphene Citrate in Pregnancy Outcomes in Patients with Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis
Comparison of Letrozole and Clomiphene Citrate in Pregnancy Outcomes in Patients with Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis
Clomiphene citrate (CC) and letrozole are the predominant medical interventions for the management of infertility in patie...
A Reliable Method for Quantifying Plasma Cell-Free DNA Using an Internal Standard Strategy: Evaluation in a Cohort of Non-Pregnant and Pregnant Women
A Reliable Method for Quantifying Plasma Cell-Free DNA Using an Internal Standard Strategy: Evaluation in a Cohort of Non-Pregnant and Pregnant Women
The use of plasma cell-free DNA (cfDNA) as a useful biomarker in obstetric clinical practice has been delayed due to the l...
Exploring the Effects of Endocrine-Disrupting Chemicals and miRNA Expression in the Pathogenesis of Endometriosis by Unveiling the Pathways: a Systematic Review
Exploring the Effects of Endocrine-Disrupting Chemicals and miRNA Expression in the Pathogenesis of Endometriosis by Unveiling the Pathways: a Systematic Review
Endometriosis, characterized by endometrial-like mucosal tissue outside the uterine cavity, is a reproductive disorder aff...
Etiology of Male Infertility: an Update
Etiology of Male Infertility: an Update
Spermatogenesis is a complex process of germ cell division and differentiation that involves extensive cross-talk between ...
Frontiers in the Etiology and Treatment of Preterm Premature Rupture of Membrane: From Molecular Mechanisms to Innovative Therapeutic Strategies
Frontiers in the Etiology and Treatment of Preterm Premature Rupture of Membrane: From Molecular Mechanisms to Innovative Therapeutic Strategies
Preterm premature rupture of membranes (pPROM) poses a significant threat to fetal viability and increases the risk for ne...
Use of Photoacoustic Imaging to Study the Effects of Anemia on Placental Oxygen Saturation in Normoxic and Hypoxic Conditions
Use of Photoacoustic Imaging to Study the Effects of Anemia on Placental Oxygen Saturation in Normoxic and Hypoxic Conditions
We aimed to evaluate fetal and placental oxygen saturation (sO2) in anemic and non-anemic pregnant rats throughout gestati...
Is Grand Multiparity an Independent Risk Factor for Blood Transfusion?
Is Grand Multiparity an Independent Risk Factor for Blood Transfusion?
The relation between grand multiparity and poor pregnancy outcome, especially postpartum hemorrhage and blood transfusion,...
Clinical Experience of Prenatal Chromosomal Microarray Analysis in 6159 Ultrasonically Abnormal Fetuses
Clinical Experience of Prenatal Chromosomal Microarray Analysis in 6159 Ultrasonically Abnormal Fetuses
A single-center retrospective study of G-band karyotyping and chromosomal microarray analysis (CMA) for the invasive prena...
Clinical Utility of Sperm Function Tests in Predicting Male Fertility: A Systematic Review
Clinical Utility of Sperm Function Tests in Predicting Male Fertility: A Systematic Review
Routine semen analysis provides considerable information regarding sperm parameters; however, it is not solely adequate to...
Down-regulation of FA-BRCA Pathway in Cervical Carcinoma Gradually Reversed During the Development of Chemo-tolerance: Clinical Implications
Down-regulation of FA-BRCA Pathway in Cervical Carcinoma Gradually Reversed During the Development of Chemo-tolerance: Clinical Implications
Cervical cancer is one of the leading causes of cancer death among females, worldwide. The contributory role of different ...
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