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A novel adiponectin receptor agonist (AdipoAI) ameliorates type 2 diabetes‐associated periodontitis by enhancing autophagy in osteoclasts.
A novel adiponectin receptor agonist (AdipoAI) ameliorates type 2 diabetes‐associated periodontitis by enhancing autophagy in osteoclasts.
Abstract Background and Objective Type 2 diabetes (T2D)-associated periodontitis is severe and refractory in many cases. C...
Herpes simplex virus type 1 in subgingival plaque and periodontal diseases. Meta‐analysis of observational studies
Herpes simplex virus type 1 in subgingival plaque and periodontal diseases. Meta‐analysis of observational studies
Abstract Background and objectives This meta-analysis of observational studies (PROSPERO registration number CRD4202123605...
Plasminogen gene polymorphisms [c.924C>T and IVS 8+14 G>A] in periodontitis and familial Mediterranean fever: A case‐control study
Plasminogen gene polymorphisms [c.924C>T and IVS 8+14 G>A] in periodontitis and familial Mediterranean fever: A case‐control study
Abstract Background and objective The plasminogen (PLG) activation system plays an essential role in severe inflammation b...
Distribution of neutrophil and monocyte/macrophage populations induced by the CXCR4 inhibitor AMD3100 in blood and periodontal tissue early after periodontitis induction
Distribution of neutrophil and monocyte/macrophage populations induced by the CXCR4 inhibitor AMD3100 in blood and periodontal tissue early after periodontitis induction
Abstract CXCR4, a CXCL12 receptor, is expressed on epithelial cells, fibroblasts, and inflammatory cells. The CXCR4-CXCL12...
Wound healing in periodontal disease induces macrophage polarization characterized by different arginine‐metabolizing enzymes
Wound healing in periodontal disease induces macrophage polarization characterized by different arginine‐metabolizing enzymes
Abstract Background and objective Macrophages play important roles from the initiation of inflammation to wound healing. T...
Abnormal hsa_circ_0003948 expression affects chronic periodontitis development by regulating miR‐144‐3p/NR2F2/PTEN signaling
Abnormal hsa_circ_0003948 expression affects chronic periodontitis development by regulating miR‐144‐3p/NR2F2/PTEN signaling
Abstract Background and Objective This study aimed to investigate the correlation between chronic periodontitis (CP) and a...
Chemomechanical preparation influences the microbial community and the levels of LPS, LTA and cytokines in combined endodontic‐periodontal lesions: A clinical study
Chemomechanical preparation influences the microbial community and the levels of LPS, LTA and cytokines in combined endodontic‐periodontal lesions: A clinical study
Abstract Background This study was conducted to compare the microbiomes, the levels of lipopolysaccharides (LPS), lipoteic...
LncRNA LOXL1‐AS1 inhibits proliferation of PDLSCs and downregulates IL‐1β in periodontitis patients
LncRNA LOXL1‐AS1 inhibits proliferation of PDLSCs and downregulates IL‐1β in periodontitis patients
Abstract Background The carcinogenic role of lncRNA LOXL1-AS1 in thoracic aortic aneurysm has been confirmed, but its role...
Interdental and subgingival microbiota may affect the tongue microbial ecology and oral malodour in health, gingivitis and periodontitis
Interdental and subgingival microbiota may affect the tongue microbial ecology and oral malodour in health, gingivitis and periodontitis
Abstract Background and Objective Oral malodour is often observed in gingivitis and chronic periodontitis patients, and th...
Food hardness can regulate orthodontic tooth movement in mice
Food hardness can regulate orthodontic tooth movement in mice
Abstract Background and objectives Orthodontic treatment is often accompanied with prescription of softer foods to patient...
The Th17/Treg cell balance: crosstalk among the immune system, bone and microbes in periodontitis
The Th17/Treg cell balance: crosstalk among the immune system, bone and microbes in periodontitis
Abstract Periodontopathic bacteria constantly stimulate the host, which causes an immune response, leading to host-induced...
Is TIMP‐1 a biomarker for periodontal disease? A systematic review and meta‐analysis
Is TIMP‐1 a biomarker for periodontal disease? A systematic review and meta‐analysis
Abstract Objective One of the most important families of proteases associated with periodontal disease is the family of th...
Is periodontitis a risk factor of benign or malignant colorectal tumor? A population‐based cohort study
Is periodontitis a risk factor of benign or malignant colorectal tumor? A population‐based cohort study
Abstract Objective To examine the risk of developing benign or malignant colorectal tumors in patients with periodontitis ...
Iron accumulation is associated with periodontal destruction in a mouse model of HFE‐related haemochromatosis
Iron accumulation is associated with periodontal destruction in a mouse model of HFE‐related haemochromatosis
Abstract Objective To investigate the effect of Hfe gene mutation on the distribution of iron and periodontal bone loss in...
Human oral mucosa‐derived neural crest‐like stem cells differentiate into functional osteoprogenitors that contribute to regeneration of critical size calvaria defects
Human oral mucosa‐derived neural crest‐like stem cells differentiate into functional osteoprogenitors that contribute to regeneration of critical size calvaria defects
Abstract Background and objective Regeneration of large bony defects is an unmet medical need. The therapeutic effect of f...
Functional Adaptation of LPS‐affected Dentoalveolar Fibrous Joints in Rats
Functional Adaptation of LPS‐affected Dentoalveolar Fibrous Joints in Rats
Abstract Introduction The functional interplay between cementum of the root and alveolar bone of the socket is tuned by a ...
Macro and trace elements signature of periodontitis in saliva: A systematic review with quality assessment of ionomics studies
Macro and trace elements signature of periodontitis in saliva: A systematic review with quality assessment of ionomics studies
Abstract Objectives The present systematic review examined the available evidence on distinctive salivary ion profile in p...
Abnormal mitochondrial structure and function are retained in gingival tissues and human gingival fibroblasts from patients with chronic periodontitis
Abnormal mitochondrial structure and function are retained in gingival tissues and human gingival fibroblasts from patients with chronic periodontitis
Abstract Background and Objective The abnormal structure and function of mitochondria in cells is closely associated with ...
Exosomes from dental pulp cells attenuate bone loss in mouse experimental periodontitis
Exosomes from dental pulp cells attenuate bone loss in mouse experimental periodontitis
Abstract Background and objective Exosomes are small vesicles secreted from many cell types. Their biological effects larg...
Molecular profiling of intrabony defects' gingival crevicular fluid
Molecular profiling of intrabony defects' gingival crevicular fluid
Abstract Aim To profile, for the first time, the gingival crevicular fluid (GCF) of intrabony defects against a wide array...
Altered human alveolar bone gene expression in type 2 diabetes—A cross‐sectional study
Altered human alveolar bone gene expression in type 2 diabetes—A cross‐sectional study
Abstract Objective The objective of this cross-sectional study is to investigate alveolar bone gene expression in health a...
Periodontal tissue engineering using an apatite/collagen scaffold obtained by a plasma‐ and precursor‐assisted biomimetic process
Periodontal tissue engineering using an apatite/collagen scaffold obtained by a plasma‐ and precursor‐assisted biomimetic process
Abstract Background and objectives In the treatment of severe periodontal destruction, there is a strong demand for advanc...
Periodontitis and Systemic Lupus Erythematosus: A systematic review and meta‐analysis
Periodontitis and Systemic Lupus Erythematosus: A systematic review and meta‐analysis
Abstract This systematic review and meta-analysis evaluated the association between periodontitis (PD) and systemic lupus ...
The emerging role of small extracellular vesicles in saliva and gingival crevicular fluid as diagnostics for periodontitis
The emerging role of small extracellular vesicles in saliva and gingival crevicular fluid as diagnostics for periodontitis
Abstract Periodontitis is a highly prevalent multifactorial chronic inflammatory disease associated with a destructive hos...
Differential regulation of NPY and SP receptor expression in STRO‐1+ve PDLSCs by inflammatory cytokines
Differential regulation of NPY and SP receptor expression in STRO‐1+ve PDLSCs by inflammatory cytokines
Abstract Objectives The aims of this study were to investigate neuropeptide receptor expression regulation on STRO-1 +ve p...
Activation of GATA‐binding protein 4 regulates monocyte chemoattractant protein‐1 and chemotaxis in periodontal ligament cells
Activation of GATA‐binding protein 4 regulates monocyte chemoattractant protein‐1 and chemotaxis in periodontal ligament cells
Abstract Background and Objectives Periodontitis is a chronic inflammatory disease of periodontal supporting tissues. The ...
In vitro evaluation of the effect of the electronic cigarette aerosol, Cannabis smoke, and conventional cigarette smoke on the properties of gingival fibroblasts/gingival mesenchymal stem cells
In vitro evaluation of the effect of the electronic cigarette aerosol, Cannabis smoke, and conventional cigarette smoke on the properties of gingival fibroblasts/gingival mesenchymal stem cells
Abstract Objective The current study aimed to evaluate the effect of electronic cigarette (EC) aerosol, Cannabis, and conv...
Inhibition of acid sphingomyelinase by imipramine abolishes the synergy between metabolic syndrome and periodontitis on alveolar bone loss
Inhibition of acid sphingomyelinase by imipramine abolishes the synergy between metabolic syndrome and periodontitis on alveolar bone loss
Abstract Background and objective Clinical studies have shown that metabolic syndrome (MetS) exacerbates periodontitis. Ho...
Surfactin reduces particulate matter–induced VCAM‐1–dependent monocyte adhesion in human gingival fibroblasts by increasing Nrf2‐dependent HO‐1 expression
Surfactin reduces particulate matter–induced VCAM‐1–dependent monocyte adhesion in human gingival fibroblasts by increasing Nrf2‐dependent HO‐1 expression
Abstract Background and objectives The mechanisms of particulate matter (PM) toxicity involve the generation of ROS and up...
Periodontal disease inequities among Indigenous populations: A systematic review and meta‐analysis
Periodontal disease inequities among Indigenous populations: A systematic review and meta‐analysis
Abstract The prevalence of periodontal disease varies considerably between Indigenous and general populations. The aim of ...
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