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The neutrophil–osteogenic cell axis promotes bone destruction in periodontitis
The neutrophil–osteogenic cell axis promotes bone destruction in periodontitis
The immune-stromal cell interactions play a key role in health and diseases. In periodontitis, the most prevalent infectio...
Tim4 deficiency reduces CD301b+ macrophage and aggravates periodontitis bone loss
Tim4 deficiency reduces CD301b+ macrophage and aggravates periodontitis bone loss
Periodontitis is a common chronic inflammatory disease that causes the periodontal bone destruction and may ultimately res...
The osteoclastic activity in apical distal region of molar mesial roots affects orthodontic tooth movement and root resorption in rats
The osteoclastic activity in apical distal region of molar mesial roots affects orthodontic tooth movement and root resorption in rats
The utilization of optimal orthodontic force is crucial to prevent undesirable side effects and ensure efficient tooth mov...
Single-cell transcriptomics reveals cell atlas and identifies cycling tumor cells responsible for recurrence in ameloblastoma
Single-cell transcriptomics reveals cell atlas and identifies cycling tumor cells responsible for recurrence in ameloblastoma
Ameloblastoma is a benign tumor characterized by locally invasive phenotypes, leading to facial bone destruction and a hig...
Expert consensus on difficulty assessment of endodontic therapy
Endodontic diseases are a kind of chronic infectious oral disease. Common endodontic treatment concepts are based on the r...
Expert consensus on irrigation and intracanal medication in root canal therapy
Chemical cleaning and disinfection are crucial steps for eliminating infection in root canal treatment. However, irrigant ...
A Wnt10a-Notch signaling axis controls Hertwig’s epithelial root sheath cell behaviors during root furcation patterning
A Wnt10a-Notch signaling axis controls Hertwig’s epithelial root sheath cell behaviors during root furcation patterning
Human with bi-allelic WNT10A mutations and epithelial Wnt10a knockout mice present enlarged pulp chamber and apical displa...
Promising dawn in tumor microenvironment therapy: engineering oral bacteria
Promising dawn in tumor microenvironment therapy: engineering oral bacteria
Despite decades of research, cancer continues to be a major global health concern. The human mouth appears to be a multipl...
Adult dental epithelial stem cell-derived organoids deposit hydroxylapatite biomineral
Adult dental epithelial stem cell-derived organoids deposit hydroxylapatite biomineral
Ameloblasts are specialized cells derived from the dental epithelium that produce enamel, a hierarchically structured tiss...
Expert consensus on digital guided therapy for endodontic diseases
Expert consensus on digital guided therapy for endodontic diseases
Digital guided therapy (DGT) has been advocated as a contemporary computer-aided technique for treating endodontic disease...
Dental impact of anti-fibroblast growth factor 23 therapy in X-linked hypophosphatemia
Dental impact of anti-fibroblast growth factor 23 therapy in X-linked hypophosphatemia
Elevated fibroblast growth factor 23 (FGF23) in X-linked hypophosphatemia (XLH) results in rickets and phosphate wasting, ...
Mesenchymal stem cell-derived apoptotic bodies alleviate alveolar bone destruction by regulating osteoclast differentiation and function
Mesenchymal stem cell-derived apoptotic bodies alleviate alveolar bone destruction by regulating osteoclast differentiation and function
Periodontitis is caused by overactive osteoclast activity that results in the loss of periodontal supporting tissue and me...
Molecular mechanisms of cellular metabolic homeostasis in stem cells
Molecular mechanisms of cellular metabolic homeostasis in stem cells
Many tissues and organ systems have intrinsic regeneration capabilities that are largely driven and maintained by tissue-r...
Titanium particles in peri-implantitis: distribution, pathogenesis and prospects
Titanium particles in peri-implantitis: distribution, pathogenesis and prospects
Peri-implantitis is one of the most important biological complications in the field of oral implantology. Identifying the ...
Spatiotemporal cellular dynamics and molecular regulation of tooth root ontogeny
Spatiotemporal cellular dynamics and molecular regulation of tooth root ontogeny
Tooth root development involves intricate spatiotemporal cellular dynamics and molecular regulation. The initiation of Her...
MLL1 inhibits the neurogenic potential of SCAPs by interacting with WDR5 and repressing HES1
MLL1 inhibits the neurogenic potential of SCAPs by interacting with WDR5 and repressing HES1
Mesenchymal stem cell (MSC)-based therapy has emerged as a promising treatment for spinal cord injury (SCI), but improving...
Sclerostin antibody improves alveolar bone quality in the Hyp mouse model of X-linked hypophosphatemia (XLH)
Sclerostin antibody improves alveolar bone quality in the Hyp mouse model of X-linked hypophosphatemia (XLH)
X-linked hypophosphatemia (XLH) is a rare disease of elevated fibroblast growth factor 23 (FGF23) production that leads to...
Oral squamous cell carcinomas: state of the field and emerging directions
Oral squamous cell carcinomas: state of the field and emerging directions
Oral squamous cell carcinoma (OSCC) develops on the mucosal epithelium of the oral cavity. It accounts for approximately 9...
Transcriptional profiling of dental sensory and proprioceptive trigeminal neurons using single-cell RNA sequencing
Transcriptional profiling of dental sensory and proprioceptive trigeminal neurons using single-cell RNA sequencing
Dental primary afferent (DPA) neurons and proprioceptive mesencephalic trigeminal nucleus (MTN) neurons, located in the tr...
Double heterozygous pathogenic mutations in KIF3C and ZNF513 cause hereditary gingival fibromatosis
Double heterozygous pathogenic mutations in KIF3C and ZNF513 cause hereditary gingival fibromatosis
Hereditary gingival fibromatosis (HGF) is a rare inherited condition with fibromatoid hyperplasia of the gingival tissue t...
Experts consensus on the procedure of dental operative microscope in endodontics and operative dentistry
Experts consensus on the procedure of dental operative microscope in endodontics and operative dentistry
The dental operative microscope has been widely employed in the field of dentistry, particularly in endodontics and operat...
Porphyromonas gingivalis, a periodontal pathogen, impairs post-infarcted myocardium by inhibiting autophagosome–lysosome fusion
Porphyromonas gingivalis, a periodontal pathogen, impairs post-infarcted myocardium by inhibiting autophagosome–lysosome fusion
While several previous studies have indicated the link between periodontal disease (PD) and myocardial infarction (MI), th...
Maxillary sinus floor augmentation: a review of current evidence on anatomical factors and a decision tree
Maxillary sinus floor augmentation: a review of current evidence on anatomical factors and a decision tree
Maxillary sinus floor augmentation using lateral window and crestal technique is considered as predictable methods to incr...
Artemisinins inhibit oral candidiasis caused by Candida albicans through the repression on its hyphal development
Artemisinins inhibit oral candidiasis caused by Candida albicans through the repression on its hyphal development
Candida albicans is the most abundant fungal species in oral cavity. As a smart opportunistic pathogen, it increases the v...
Publisher Correction: The interaction between the nervous system and the stomatognathic system: from development to diseases
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Single-cell transcriptomic analysis uncovers the origin and intratumoral heterogeneity of parotid pleomorphic adenoma
Single-cell transcriptomic analysis uncovers the origin and intratumoral heterogeneity of parotid pleomorphic adenoma
Pleomorphic adenoma (PA) is the most common benign tumour in the salivary gland and has high morphological complexity. How...
Knockdown of PGC1α suppresses dysplastic oral keratinocytes proliferation through reprogramming energy metabolism
Knockdown of PGC1α suppresses dysplastic oral keratinocytes proliferation through reprogramming energy metabolism
Oral potentially malignant disorders (OPMDs) are precursors of oral squamous cell carcinoma (OSCC). Deregulated cellular e...
Divergent chondro/osteogenic transduction laws of fibrocartilage stem cell drive temporomandibular joint osteoarthritis in growing mice
Divergent chondro/osteogenic transduction laws of fibrocartilage stem cell drive temporomandibular joint osteoarthritis in growing mice
The anterior disc displacement (ADD) leads to temporomandibular joint osteoarthritis (TMJOA) and mandibular growth retarda...
Atp6i deficient mouse model uncovers transforming growth factor-β1 /Smad2/3 as a key signaling pathway regulating odontoblast differentiation and tooth root formation
Atp6i deficient mouse model uncovers transforming growth factor-β1 /Smad2/3 as a key signaling pathway regulating odontoblast differentiation and tooth root formation
The biomolecular mechanisms that regulate tooth root development and odontoblast differentiation are poorly understood. We...
The interaction between the nervous system and the stomatognathic system: from development to diseases
The interaction between the nervous system and the stomatognathic system: from development to diseases
The crosstalk between the nerve and stomatognathic systems plays a more important role in organismal health than previousl...
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