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STAT6 mutations enriched at diffuse large B-cell lymphoma relapse reshape the tumor microenvironment
STAT6 mutations enriched at diffuse large B-cell lymphoma relapse reshape the tumor microenvironment
Diffuse large B-cell lymphoma (DLBCL) relapses in approximately 40% of patients following frontline therapy. We reported t...
Diffuse large B-cell lymphoma of the skull vault
Diffuse large B-cell lymphoma of the skull vault
Matejka M, Moreno Beredjiklian C, Rezai A, Kraus TFJ, Pizem D, Klausner F, et al. Extra- and intracranial diffuse large B-...
Histiocytic sarcoma following CAR T-cell therapy: a case report
Histiocytic sarcoma following CAR T-cell therapy: a case report
Development of secondary tumor after CART treatment is not well investigated. We report a pediatric B-cell acute lymphobla...
A case report of a truncated ABL1 mutation in 2 cases with Philadelphia chromosome-positive B cell precursor acute lymphoblastic leukemia
A case report of a truncated ABL1 mutation in 2 cases with Philadelphia chromosome-positive B cell precursor acute lymphoblastic leukemia
Acquired point mutations in the ABL1 gene are widely recognized as a cause of Philadelphia chromosome-positive B cell prec...
Emicizumab-mediated hemostatic function assessed by thrombin generation assay in an in vitro model of factor VIII-depleted thrombophilia plasma
Emicizumab-mediated hemostatic function assessed by thrombin generation assay in an in vitro model of factor VIII-depleted thrombophilia plasma
Patients with hemophilia A (PwHA) may have concurrent deficiency of representative anticoagulant proteins, protein (P)C, P...
Auer rods in mature granulocytes in peripheral blood
Auer rods in mature granulocytes in peripheral blood
Conflict of interest All authors have no competing interest...
Abnormal bone marrow T1-weighted MRI images in a pediatric patient with acute lymphoblastic leukemia without peripheral blasts
Abnormal bone marrow T1-weighted MRI images in a pediatric patient with acute lymphoblastic leukemia without peripheral blasts
Cite this articleOyake, M., Hirakuni, Y., Hirano, N. et al. Abnormal bone marrow T1-weighted MRI images in a pediatric pat...
HLA haploidentical stem cell transplantation from HLA homozygous donors to HLA heterozygous donors may have lower survival rates than haploidentical transplantation from HLA heterozygous donors to HLA heterozygous donors: a retrospective nationwide analysis
HLA haploidentical stem cell transplantation from HLA homozygous donors to HLA heterozygous donors may have lower survival rates than haploidentical transplantation from HLA heterozygous donors to HLA heterozygous donors: a retrospective nationwide analysis
In HLA haploidentical stem cell transplantation, patients and donors usually share one HLA haplotype and have one differen...
Comparison of standardized prophylactic high-dose and intrathecal methotrexate for DLBCL with a high risk of CNS relapse
Comparison of standardized prophylactic high-dose and intrathecal methotrexate for DLBCL with a high risk of CNS relapse
The efficacy of high-dose methotrexate (HD-MTX) for central nervous system (CNS) relapse prophylaxis in patients with high...
Real-world data of MDS and CMML in Japan: results of JALSG clinical observational study-11 (JALSG-CS-11)
Real-world data of MDS and CMML in Japan: results of JALSG clinical observational study-11 (JALSG-CS-11)
We conducted a multicenter, prospective observational study of acute myeloid leukemia (AML), myelodysplastic syndromes (MD...
SPAG6 regulates cell proliferation and apoptosis via TGF-β/Smad signal pathway in adult B-cell acute lymphoblastic leukemia
SPAG6 regulates cell proliferation and apoptosis via TGF-β/Smad signal pathway in adult B-cell acute lymphoblastic leukemia
Adult B-cell acute lymphoblastic leukemia (B-ALL) prognosis remains unsatisfactory, and searching for new therapeutic targ...
Japanese phase Ib study of the oral PI3K-δ and -γ inhibitor duvelisib in patients with relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma
Japanese phase Ib study of the oral PI3K-δ and -γ inhibitor duvelisib in patients with relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma
This phase Ib, open-label, single-arm, multicenter study assessed the efficacy and safety of duvelisib, an oral dual inhib...
Anticoagulant effects of protein C, protein S, and antithrombin levels on the protein C pathway in young children
Anticoagulant effects of protein C, protein S, and antithrombin levels on the protein C pathway in young children
The protein C (PC) pathway involves physiological anticoagulant factors (PC, protein S [PS], and factor V) and performs ma...
Real-world effectiveness and safety of ibrutinib in relapsed/refractory mantle cell lymphoma in Japan: post-marketing surveillance
Real-world effectiveness and safety of ibrutinib in relapsed/refractory mantle cell lymphoma in Japan: post-marketing surveillance
Efficacy and safety data for ibrutinib in Japanese patients with relapsed/refractory (R/R) mantle cell lymphoma (MCL) were...
Nelarabine-containing salvage therapy and conditioning regimen in transplants for pediatric T-cell acute lymphoblastic leukemia and lymphoma
Nelarabine-containing salvage therapy and conditioning regimen in transplants for pediatric T-cell acute lymphoblastic leukemia and lymphoma
Therapy for relapsed or refractory (r/r) T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-...
Characteristics and prognosis of patients with COVID-19 and hematological diseases in Japan: a cross-sectional study
Characteristics and prognosis of patients with COVID-19 and hematological diseases in Japan: a cross-sectional study
The Japanese Society of Hematology performed an observational cross-sectional study to clarify the morbidity, prognosis, a...
Congenital dyserythropoietic anemia type II in a newborn with a novel compound heterozygous mutation in the SEC23B: a case report and review of the literature
Congenital dyserythropoietic anemia type II in a newborn with a novel compound heterozygous mutation in the SEC23B: a case report and review of the literature
Congenital dyserythropoietic anemia type II (CDA II) refers to a group of extremely rare heterozygous disorders characteri...
Cancer-associated thrombosis and bleeding
Cancer-associated thrombosis and bleeding
Development of thrombosis is closely associated with poor prognosis in cancer patients. Cancer patients often fulfill Virc...
Real-world data of AML in Japan: results of JALSG clinical observational study-11 (JALSG-CS-11)
Real-world data of AML in Japan: results of JALSG clinical observational study-11 (JALSG-CS-11)
This report covers acute myeloid leukemia (AML) results from a multicenter, prospective observational study of AML, myelod...
Histopathological maturation in juvenile xanthogranuloma: a blueberry muffin infant mimicking aleukemic leukemia cutis
Histopathological maturation in juvenile xanthogranuloma: a blueberry muffin infant mimicking aleukemic leukemia cutis
Juvenile xanthogranuloma (JXG) is usually identified by Touton giant cells, so their absence can complicate diagnosis. We ...
Effectiveness of venetoclax and azacytidine against myeloid/natural killer cell precursor acute leukemia
Effectiveness of venetoclax and azacytidine against myeloid/natural killer cell precursor acute leukemia
Myeloid/natural killer (NK) cell precursor acute leukemia (MNKPL) is a rare leukemia subtype that possibly originates from...
Association of CD8 + T cells expressing nivolumab-free PD-1 with clinical status in a patient with relapsed refractory classical Hodgkin lymphoma
Association of CD8 + T cells expressing nivolumab-free PD-1 with clinical status in a patient with relapsed refractory classical Hodgkin lymphoma
A 37-year-old man with refractory classical Hodgkin lymphoma (cHL) underwent PD-1 blockade therapy with nivolumab, which r...
Clonal hematopoiesis of a novel dic(18;20) clone following allogeneic hematopoietic stem cell transplantation
Clonal hematopoiesis of a novel dic(18;20) clone following allogeneic hematopoietic stem cell transplantation
A 55-year-old man in first complete remission of acute myeloid leukemia with a normal karyotype underwent allogeneic hemat...
Multicenter evaluation of the addition of eltrombopag to immunosuppressive therapy for adults with severe aplastic anemia
Multicenter evaluation of the addition of eltrombopag to immunosuppressive therapy for adults with severe aplastic anemia
Eltrombopag has been shown to improve response rates when added to standard therapy in adults with severe aplastic anemia ...
Successful allogeneic hematopoietic stem cell transplantation for myelodysplastic neoplasms complicated with secondary pulmonary alveolar proteinosis and Behçet's disease harboring GATA2 mutation
Successful allogeneic hematopoietic stem cell transplantation for myelodysplastic neoplasms complicated with secondary pulmonary alveolar proteinosis and Behçet's disease harboring GATA2 mutation
Myelodysplastic neoplasms (MDS) are defined by cytopenia and morphologic dysplasia originating from clonal hematopoiesis. ...
Fludarabine melphalan versus fludarabine treosulfan for reduced intensity conditioning regimen in allogeneic hematopoietic stem cell transplantation: a retrospective analysis
Fludarabine melphalan versus fludarabine treosulfan for reduced intensity conditioning regimen in allogeneic hematopoietic stem cell transplantation: a retrospective analysis
Various reduced-intensity conditioning (RIC) regimens are used to decrease toxicity while providing comparable outcomes to...
Reference guide for the diagnosis of adult primary immune thrombocytopenia, 2023 edition
Reference guide for the diagnosis of adult primary immune thrombocytopenia, 2023 edition
Primary immune thrombocytopenia (ITP) is an autoimmune disorder characterized by isolated thrombocytopenia due to accelera...
Risk factors associated with infection-related mortality of Bacillus cereus bacteremia in hematologic disorders
Risk factors associated with infection-related mortality of Bacillus cereus bacteremia in hematologic disorders
The mortality risk factors in B. cereus bacteremia in hematologic disorders are still unknown. In this study, patients wit...
Clinical implications of augmented renal clearance after unrelated single cord blood transplantation in adults
Clinical implications of augmented renal clearance after unrelated single cord blood transplantation in adults
Augmented renal clearance (ARC) is a phenomenon characterized by increased renal functionality, which can impact the pharm...
Hematopoiesis in the spleen after engraftment in unrelated cord blood transplantation evaluated by 18F-FLT PET imaging
Hematopoiesis in the spleen after engraftment in unrelated cord blood transplantation evaluated by 18F-FLT PET imaging
Cord blood is an important donor source for allogeneic hematopoietic stem cell transplantation (allo-HSCT), with its uniqu...
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