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Contribution of higher risk genes and European admixture to Crohn's disease in African Americans
Contribution of higher risk genes and European admixture to Crohn's disease in African Americans
Abstract Background: African Americans (AAs) are an admixed population of West African (WA) and European ancestry (EA). Cr...
Mood disorders in inflammatory bowel disease: Relation to diagnosis, disease activity, perceived stress, and other factors
Mood disorders in inflammatory bowel disease: Relation to diagnosis, disease activity, perceived stress, and other factors
Abstract Background: Anxiety and depression are common in patients with inflammatory bowel disease (IBD); however, the fac...
Setting priorities for comparative effectiveness research in inflammatory bowel disease: Results of an international provider survey, expert rand panel, and patient focus groups
Setting priorities for comparative effectiveness research in inflammatory bowel disease: Results of an international provider survey, expert rand panel, and patient focus groups
Abstract Background: Comparative effectiveness research (CER) is an emerging field that compares the relative effectivenes...
Prospective study of the progression of low‐grade dysplasia in ulcerative colitis using current cancer surveillance guidelines
Prospective study of the progression of low‐grade dysplasia in ulcerative colitis using current cancer surveillance guidelines
Abstract Background: The goal of this study was to assess the natural history of low-grade dysplasia (LGD) and its risk of...
Immune markers and differential signaling networks in ulcerative colitis and Crohn's disease
Immune markers and differential signaling networks in ulcerative colitis and Crohn's disease
Abstract Background: Cytokine signaling pathways play a central role in the pathogenesis of inflammatory bowel disease (IB...
Clinical implications of variations in anti‐infliximab antibody levels in patients with inflammatory bowel disease
Clinical implications of variations in anti‐infliximab antibody levels in patients with inflammatory bowel disease
Abstract Background: The aim of the study was to investigate variations in anti-infliximab (IFX) antibody (Ab) levels and ...
Primary sclerosing cholangitis is associated with a distinct phenotype of inflammatory bowel disease
Primary sclerosing cholangitis is associated with a distinct phenotype of inflammatory bowel disease
Abstract Background: Primary sclerosing cholangitis (PSC) is strongly associated with inflammatory bowel disease (IBD). Th...
Detection and differentiation of inflammatory versus fibromatous Crohn's disease strictures: Prospective comparison of 18F‐FDG‐PET/CT, MR‐enteroclysis, and transabdominal ultrasound versus endoscopic/histologic evaluation
Detection and differentiation of inflammatory versus fibromatous Crohn's disease strictures: Prospective comparison of 18F‐FDG‐PET/CT, MR‐enteroclysis, and transabdominal ultrasound versus endoscopic/histologic evaluation
Abstract Background: Differentiation between inflammatory and fibromatous strictures in Crohn's disease (CD) is difficult ...
When independent healthcare behaviors develop in adolescents with inflammatory bowel disease
When independent healthcare behaviors develop in adolescents with inflammatory bowel disease
Abstract Background: Patients with chronic health needs are expected to gradually assume responsibility for health mainten...
Response to biologic therapy in Crohn's disease is improved with early treatment: An analysis of health claims data
Response to biologic therapy in Crohn's disease is improved with early treatment: An analysis of health claims data
Abstract Background: Anti-tumor necrosis factor (TNF) therapy is an important treatment option for management of active Cr...
Role of LFA‐1 in the activation and trafficking of T cells: Implications in the induction of chronic colitis
Role of LFA‐1 in the activation and trafficking of T cells: Implications in the induction of chronic colitis
Abstract Introduction: We have previously demonstrated that adoptive transfer of naïve CD4+ T cells devoid of lymphoc...
Natalizumab for moderate to severe Crohn's disease in clinical practice: The Mayo Clinic Rochester experience
Natalizumab for moderate to severe Crohn's disease in clinical practice: The Mayo Clinic Rochester experience
Abstract Background: Not all patients with Crohn's disease (CD) respond or maintain response to anti-tumor necrosis factor...
Assessment of Crohn's disease activity by confocal laser endomicroscopy
Assessment of Crohn's disease activity by confocal laser endomicroscopy
Abstract Background: Confocal laser endomicroscopy (CLE) allows microscopic imaging within the mucosal layer of the gut du...
Plasmablast frequency and trafficking receptor expression are altered in pediatric ulcerative colitis
Plasmablast frequency and trafficking receptor expression are altered in pediatric ulcerative colitis
Abstract Background: The incidence of pediatric ulcerative colitis (UC), a chronic autoinflammatory disease of the colon, ...
Bioinformatics analysis reveals transcriptome and microRNA signatures and drug repositioning targets for IBD and other autoimmune diseases
Bioinformatics analysis reveals transcriptome and microRNA signatures and drug repositioning targets for IBD and other autoimmune diseases
Abstract Background: Inflammatory bowel disease (IBD) is a complex disorder involving pathogen infection, host immune resp...
Decreased mucosal sulfide detoxification is related to an impaired butyrate oxidation in ulcerative colitis
Decreased mucosal sulfide detoxification is related to an impaired butyrate oxidation in ulcerative colitis
Abstract Background: Defective detoxification of sulfides leads to damage to the mucosa and may play a role in the etiolog...
Geographic distributions of microscopic colitis and inflammatory bowel disease in the United States
Geographic distributions of microscopic colitis and inflammatory bowel disease in the United States
Abstract Background: Crohn's disease (CD) and ulcerative colitis (UC) are characterized by similar geographic distribution...
Anti‐TNFs and severe infections in autoimmune diseases: The other side of the coin
Anti‐TNFs and severe infections in autoimmune diseases: The other side of the coin
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Colorectal cancer in inflammatory bowel diseases: A population‐based study (1976–2008)
Colorectal cancer in inflammatory bowel diseases: A population‐based study (1976–2008)
Abstract Background: Few data are available on the incidence, characteristics, treatment, and prognosis of inflammatory bo...
Adalimumab therapy in Crohn's disease of the ileal pouch
Adalimumab therapy in Crohn's disease of the ileal pouch
Abstract Background: Crohn's disease (CD) of the pouch can develop in patients with ileal pouch–anal anastomosis, r...
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