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3D Spongin-Based Scaffolds from Marine Demosponge Haliclona sp. for Biomedical Engineering Approaches Based on Mesenchymal Stem Cells
Spongin is a versatile organic protein derived from marine sponges, similar to collagen. It has high elasticity after hydr...
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3D-Printed Polymer Scaffolds for Vascularized Bone Regeneration Using Mineral and Extracellular Matrix Deposition
Trauma, injury, disease, infection, congenital deformities, and non-union after a fracture can lead to significant loss of...
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Silk Fibroin–Based Biomaterial Scaffold in Tissue Engineering: Present Persuasive Perspective
A significant naturally occurring fibrous protein, silk fibroin has great potential for use in tissue engineering. The tec...
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Cytoprotective and Neuroinductive Effects of Thiol-Containing Simple Signaling Molecules
Around 20 million Americans, mostly young adults, have suffered from a peripheral nerve injury due to trauma or a medical ...
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Discovering Tumor Microenvironment Dynamics in HPV-Associated Cancers: Using Organoid-Based Models to Develop Therapeutics
Human papillomavirus (HPV) is a pervasive sexually transmitted infection associated with various cancers, including cervic...
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Characterization of the pH-Dependent Disintegration of Chemically Modified Alginate Hydrogels
We previously showed that chemical modification of alginate with 4-(2-aminoethyl) benzoic acid (ABA) results in the ...
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A Comprehensive Exploration of Polymeric 3D Sponges for Regeneration of Bone
Bone regeneration through tissue engineering is a promising domain aiming to regenerate damaged bone tissue, requiring sui...
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Revolutionizing Tooth Regeneration: Innovations from Stem Cells to Tissue Engineering
Tooth regeneration research seeks to revolutionize regenerative dentistry by integrating advanced tissue engineering and b...
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Comprehensive Exploration on Chemical Functionalization and Crosslinked Injectable Hyaluronic Acid Hydrogels for Tissue Engineering Applications
Growing knowledge of the physical and biological attributes of hyaluronic acid (HA) led to its application as a bioactive ...
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Unravelling the Potential of Carboxymethyl Cellulose Hydrogels for Articular Cartilage Repair: A Rat Model Study
Articular cartilage injuries pose significant challenges for regenerative medicine, necessitating the development of innov...
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Wound Healing Effect of PRP-Induced MSC Secretome Under High Glucose Conditions: An In Vitro Study
Diabetic wounds represent a major health burden, and treatment involves skin grafting, tissue-engineered approaches, and c...
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3D-Printed Polyurethane Scaffolds for Bone Tissue Engineering: Techniques and Emerging Applications
The primary purpose of this review article is to provide a comprehensive analysis of polyurethane (PU)-based 3D-printed sc...
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Umbilical Cord-derived Mesenchymal Stem Cells (CLV-100) Infusion in Healthy Subjects: a 5-Year Follow-up Study on Safety and Immunomodulatory Effect
Umbilical cord-derived mesenchymal stem cells (UCMSCs) have garnered significant attention in the field of regenerative me...
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Novel Apexification Procedure as a Biotic Treatment Approach Using Amniotic Membrane Matrix and Biodentin Obturation for Immature Permanent Teeth: Case Series with Review of Literature
Regenerative therapy’s primary goal in endodontics is to revitalize the pulpo-dentinal system of immature permanent ...
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A Review on Magnesium Matrix Composites for Biomedical Applications: Materials, Fabrication Techniques, Coatings, and Applications
This review investigates the development and enhancement of magnesium matrix composites (Mg-MMCs) for biomedical applicati...
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Meticulous Standards for Bio-relevant Method Development and Validation of In Vitro Release Testing for Regenerative Topicals: A Comprehensive Review
In vitro release testing (IVRT) is an essential analytical method used to assess the bioequivalence of semi-solid dosage f...
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Decellularized Extracellular Matrix-Derived Hydrogels: a Powerful Class of Biomaterials for Skeletal Muscle Regenerative Engineering Applications
The extracellular matrix (ECM) is a complicated milieu consisting of structural and functional molecules secreted by the r...
Regenerative Engineering And Translational Medicine
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Biodegradable Polyphosphazenes for Biomedical Applications
Polyphosphazenes are an important class of biodegradable polymers with immense biomedical potential. These polymers consis...
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Hydrogels Loaded with Mesenchymal Stem Cells Extracellular Vesicles for Treating Knee Joint Disorders: A Systematic Review
Knee joints are prone to injuries and degenerative diseases; however, current treatments have limited effectiveness in car...
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Impact of Platelet-Rich Plasma and Adipose-Derived Stromal Vascular Fraction on Atrophic Non-union Fracture Healing in a Rabbit Model
Bone substitutes provide mechanical support to the healing bone and promote osteoconduction. The present study evaluated t...
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Regenerative Engineering of a Limb: From Amputation to Regeneration
This work is a summary of regeneration mechanisms and some important aspects of cellular and molecular factors in regenera...
Regenerative Engineering And Translational Medicine
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Fat Expansion Not Fat Infiltration of Muscle Post Rotator Cuff Tendon Tears of the Shoulder: Regenerative Engineering Implications
Rotator cuff (RC) tears affect many individuals around the globe. Ambiguity of rotator cuff repair surgical outcomes is cu...
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Neuroprotective Effects of Wharton Jelly Stem Cell-Derived Exosomes Developed as Nano-Drug Delivery System in 6-OHDA-Induced Neurotoxicity in 2D and 3D Neuronal Cell Line
The underlying mechanism of today’s neurodegenerative diseases is disordered due to neuronal damage and very limited...
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Current Trends in the Treatment of Traumatic Nail Injuries and the Prospect of Solutions from Regenerative Engineering
When a catastrophic loss occurs, reconstructing the nail and nail bed can be difficult. In this review, we evaluated the c...
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Amnion-Based Biomaterials for Musculoskeletal Regenerative Engineering
Amnion is used as a biomaterial for musculoskeletal tissue regeneration due to its unique properties, including biocompati...
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Biological Materials Introduced to the Market for Blurred Cornea Regeneration
Corneal diseases are the fourth reason for blindness around the world which can be treated with corneal transplantation as...
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Classes of Stem Cells: From Biology to Engineering
The majority of adult tissues are limited in self-repair and regeneration due to their poor intrinsic regenerative capacit...
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Correlation Between Alkaline Phosphatase Expression and Sox2, Oct4, and Nanog Genes in Spermatogonial and ES-Like Cells
The signaling pathway of spermatogenesis may be identified by analyzing and contrasting the similarities and differences i...
Regenerative Engineering And Translational Medicine
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A Comprehensive Review on Natural Therapeutics for Wound Treatment
Wound healing is a biological process that plays an important role in tissue recovery and reconstruction of damaged tissue...
Regenerative Engineering And Translational Medicine
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Human Macrophage- and Osteoclast-Based Constructs Do Not Induce Ectopic Bone Formation
An increasing body of evidence suggests that bone resorbing osteoclasts are important—but as yet underrated—ce...
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