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Influence of standard culture conditions and effect of oleoresin from the microalga Haematococcus pluvialis on splenic cells from healthy Balb/c mice — a pilot study
Influence of standard culture conditions and effect of oleoresin from the microalga Haematococcus pluvialis on splenic cells from healthy Balb/c mice — a pilot study
In this work, we used splenocytes from healthy mice to study the effects of the two most commonly used cell culture media ...
Downregulation of BUBR1 regulates the proliferation and cell cycle of breast cancer cells and increases the sensitivity of cells to cisplatin
Downregulation of BUBR1 regulates the proliferation and cell cycle of breast cancer cells and increases the sensitivity of cells to cisplatin
Breast cancer (BC) is a significant tissue for women’s health worldwide. The spindle assembly checkpoint protein fam...
Epigallocatechin gallate inhibits ovarian cancer cell growth and induces cell apoptosis via activation of FOXO3A
Epigallocatechin gallate inhibits ovarian cancer cell growth and induces cell apoptosis via activation of FOXO3A
Epigallocatechin gallate (EGCG), a bioactive component in tea, displays broad anti-cancer effects. Our study was designed ...
Myricetin ameliorates the IL-21-induced tumorigenic phenotype of adjuvant-induced arthritis FLS by modulating the choline kinase signaling cascade
Myricetin ameliorates the IL-21-induced tumorigenic phenotype of adjuvant-induced arthritis FLS by modulating the choline kinase signaling cascade
The synovial intimal lining is mainly governed by fibroblast-like synoviocytes (FLS), which portray a transformed tumor-li...
Correction: CD142 promotes trophoblast cell migration by inhibiting BCL2-related autophagic degradation of IL-8
Correction: CD142 promotes trophoblast cell migration by inhibiting BCL2-related autophagic degradation of IL-8
Authors and AffiliationsDepartment of Obstetrics, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical Un...
Cytotoxicity of the field lampricide 3-trifluoromethyl-4-nitrophenol (TFM) in tadpole cell lines from North American frogs
Cytotoxicity of the field lampricide 3-trifluoromethyl-4-nitrophenol (TFM) in tadpole cell lines from North American frogs
The common field lampricide, 3-trifluoromethyl-4-nitrophenol (TFM), is used to treat streams and creeks infested with high...
Ghrelin inhibits NLRP3 inflammasome activation by upregulating autophagy to improve Alzheimer’s disease
Ghrelin inhibits NLRP3 inflammasome activation by upregulating autophagy to improve Alzheimer’s disease
Nod-like receptor protein 3 (NLRP3) inflammasome, autophagy, and the aggregation of β-amyloid (Aβ) are key facto...
Vardenafil alleviates cigarette smoke-induced chronic obstructive pulmonary disease by activating autophagy via the AMPK/mTOR signalling pathway: an in vitro and in vivo study
Vardenafil alleviates cigarette smoke-induced chronic obstructive pulmonary disease by activating autophagy via the AMPK/mTOR signalling pathway: an in vitro and in vivo study
Chronic obstructive pulmonary disease (COPD) has always attracted global attention with its high prevalence, incidence rat...
Identification of highly active compounds from insecticidal plant Oroxylum indicum L. (Vent.) and the induction of apoptosis by lapachol on Sf9 cells
Identification of highly active compounds from insecticidal plant Oroxylum indicum L. (Vent.) and the induction of apoptosis by lapachol on Sf9 cells
The extraction of biopesticides from plants has become a promising field for agricultural development. To explore a high-e...
Anti-oxidative activities and anti-ferroptosis of conditioned medium from umbilical cord mesenchymal stem cells
Anti-oxidative activities and anti-ferroptosis of conditioned medium from umbilical cord mesenchymal stem cells
The therapeutic effect of MSC is closely related to its antioxidant capacity. There is no uniform standard for evaluating ...
Establishment of SLC7A11‐knockout mouse and its preliminary investigation in melanoma
Establishment of SLC7A11‐knockout mouse and its preliminary investigation in melanoma
Solute carrier family 7 member 11 (SLC7A11)/xCT is an amino acid transporter that mediates the cystine uptake and glutamat...
Curculigoside attenuates osteoporosis through regulating DNMT1 mediated osteoblast activity
Curculigoside attenuates osteoporosis through regulating DNMT1 mediated osteoblast activity
This work aims to study the function of curculigoside in osteoporosis and explore whether DNMT1 is closely involved in ost...
Ecliptasaponin A attenuates renal fibrosis by regulating the extracellular matrix of renal tubular cells
Ecliptasaponin A attenuates renal fibrosis by regulating the extracellular matrix of renal tubular cells
Renal fibrosis is the most common manifestation of end-stage renal disease (ESRD), including di...
Drynaria Naringin alleviated mechanical stress deficiency-caused bone loss deterioration via Rspo1/Lgr4-mediated Wnt/β-catenin signalling pathway
Drynaria Naringin alleviated mechanical stress deficiency-caused bone loss deterioration via Rspo1/Lgr4-mediated Wnt/β-catenin signalling pathway
Osteoporosis is a metabolic condition distinguished by the degradation of bone microstructure and mechanical characteristi...
Ulinastatin ameliorates podocyte ferroptosis via regulating miR-144-3p/SLC7A11 axis in acute kidney injury
Ulinastatin ameliorates podocyte ferroptosis via regulating miR-144-3p/SLC7A11 axis in acute kidney injury
Ferroptosis is a newly discovered form of cell death characterized by intracellular iron accumulation and subsequent lipid...
HIF-1α-induced upregulation of m6A reader IGF2BP1 facilitates peripheral nerve injury recovery by enhancing SLC7A11 mRNA stabilization
HIF-1α-induced upregulation of m6A reader IGF2BP1 facilitates peripheral nerve injury recovery by enhancing SLC7A11 mRNA stabilization
The recovery of peripheral nerve injury (PNI) is not ideal in clinic. Our previous study revealed that hypoxia treatment p...
Ubiquitination of ASCL1 mediates CD47 transcriptional activation of the AKT signaling pathway, and glycolysis promotes osteogenic differentiation of hBMSCs
Ubiquitination of ASCL1 mediates CD47 transcriptional activation of the AKT signaling pathway, and glycolysis promotes osteogenic differentiation of hBMSCs
Bones are extremely dynamic organs that continually develop and remodel. This process involves changes in numerous gene ex...
TRIM9 promotes Müller cell–derived retinal stem cells to differentiate into retinal ganglion cells by regulating Atoh7
TRIM9 promotes Müller cell–derived retinal stem cells to differentiate into retinal ganglion cells by regulating Atoh7
Glaucoma is a multifactorial, irreversible blinding eye disease characterized by a large number of retinal ganglion cell (...
Punicalagin relieves lipotoxic injuries on pancreatic β-cells via regulating the oxidative stress and endoplasmic reticulum stress-mediated apoptosis
Punicalagin relieves lipotoxic injuries on pancreatic β-cells via regulating the oxidative stress and endoplasmic reticulum stress-mediated apoptosis
Cellular toxicity of hyperlipidemia has been long considered a major cause of various intractable disease such as diabetes...
Platelet factor 4 (PF4) induces cluster of differentiation 40 (CD40) expression in human aortic endothelial cells (HAECs) through the SIRT1/NF-κB/p65 signaling pathway
Platelet factor 4 (PF4) induces cluster of differentiation 40 (CD40) expression in human aortic endothelial cells (HAECs) through the SIRT1/NF-κB/p65 signaling pathway
PF4 is a pro-atherosclerotic molecule. Endothelial CD40, upon binding to its ligand CD40L, induces endothelial cell (EC) a...
In vitro inhibitory effect of zingerone on TNFα-stimulated fibroblast-like synoviocytes
In vitro inhibitory effect of zingerone on TNFα-stimulated fibroblast-like synoviocytes
Targeting Fibroblast-like synoviocytes (FLSs) is an attractive complementary approach for RA therapy. This study aimed to ...
Knockdown of ZnT4 Induced Apoptosis, Inhibited Proliferation and testosterone synthesis of TM3 cells
Knockdown of ZnT4 Induced Apoptosis, Inhibited Proliferation and testosterone synthesis of TM3 cells
Zinc deficiency has a huge impact on male reproduction. The zinc transporter (ZnT) family is involved in the maintenance o...
Effect of Wnt10a/β-catenin signaling pathway on promoting the repair of different types of dentin-pulp injury
Effect of Wnt10a/β-catenin signaling pathway on promoting the repair of different types of dentin-pulp injury
How to repair dentin-pulp injury effectively has always been a clinical problem, and the comparative study of repair proce...
Culture methods focusing on bile canalicular formation using primary human hepatocytes in a short time
Culture methods focusing on bile canalicular formation using primary human hepatocytes in a short time
The development of models for predicting hepatotoxicity is warranted, as the hepatotoxicity risk of 38–51% of compou...
Characteristics of mesenchymal stem cells and their exosomes derived from giant panda (Ailuropoda melanoleuca) endometrium
Characteristics of mesenchymal stem cells and their exosomes derived from giant panda (Ailuropoda melanoleuca) endometrium
Conservation of genetic resources is an important way to protect endangered species. At present, mesenchymal stem cells (M...
Equine induced pluripotent stem cells are responsive to inflammatory cytokines before and after differentiation into musculoskeletal cell types
Equine induced pluripotent stem cells are responsive to inflammatory cytokines before and after differentiation into musculoskeletal cell types
Persistent inflammation is associated with the poor regeneration of musculoskeletal tissues. Embryonic stem cells (ESCs) h...
Thiopental sodium attenuates hypoxia/reoxygenation-induced injury in osteoblasts by modulating AKT signaling
Thiopental sodium attenuates hypoxia/reoxygenation-induced injury in osteoblasts by modulating AKT signaling
Thiopental sodium (TPTS) is a barbiturate general anesthetic, while its effects on hypoxia/reoxygenation (H/R)-induced inj...
Establishment and characterization of a novel kidney cell line derived from the common bottlenose dolphin
Establishment and characterization of a novel kidney cell line derived from the common bottlenose dolphin
Common bottlenose dolphin (Tursiops truncatus) is a well-known cetacean species that inhabits temperate and tropical seas ...
Reversible suspension culture of human vascular smooth muscle cells using the functional biopolymer FP003
Reversible suspension culture of human vascular smooth muscle cells using the functional biopolymer FP003
Human vascular smooth muscle cells (SMCs) are adherent cells, and they cannot survive without scaffolds in suspension cult...
FAM3A mediates the phenotypic switch of human aortic smooth muscle cells stimulated with oxidised low-density lipoprotein by influencing the PI3K-AKT pathway
FAM3A mediates the phenotypic switch of human aortic smooth muscle cells stimulated with oxidised low-density lipoprotein by influencing the PI3K-AKT pathway
Family with sequence similarity 3 member A (FAM3A) is a multifunctional protein that is related to the pathological proces...
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