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The Value of Measuring Lipoprotein(a) in Children
Michael Khoury Correspondence to: Michael Khoury, MD, Pediatric Cardiology, Department of Pediatrics, Stollery Children’s ...
Cardiovascular Disease Among Persons Living With HIV: New Insights Into Pathogenesis and Clinical Manifestations in a Global Context
Widespread use of contemporary antiretroviral therapy globally has transformed HIV disease into a chronic illness associat...
Tackling Adversity and Cardiovascular Health: It is About Time
Tackling Adversity and Cardiovascular Health: It is About Time
Michelle A. Albert Correspondence to: Michelle A. Albert, MD, MPH, University of California, San Francisco, 505 Parnassus ...
Recognized Outstanding Reviewers for Circulation in 2022
Darren K. McGuire Correspondence to: Darren K. McGuire, MD, MHSc, University of Texas Southwestern Medical Center, Interna...
Adults With Congenital Heart Disease: Trends in Event-Free Survival Past Middle Age
BACKGROUND: The survival of children with congenital heart disease has increased substantially over the past decades, with...
The MIDA-Q Mortality Risk Score: A Quantitative Prognostic Tool for the Mitral Valve Prolapse Spectrum
BACKGROUND: Mitral valve prolapse (MVP) is responsible for a considerable disease burden but is widely heterogeneous. The ...
Peptide Vaccine Against ADAMTS-7 Ameliorates Atherosclerosis and Postinjury Neointima Hyperplasia
BACKGROUND: The metalloprotease ADAMTS-7 (a disintegrin and metalloproteinase with thrombospondin type 1 motif 7) is a nov...
What Is the Future of Factor XI Inhibitors?
Jeffrey I. Weitz Correspondence to: Jeffrey Weitz, Thrombosis and Atherosclerosis Research Institute, 237 Barton Street Ea...
Straight to the Heart: T Cells That Specifically Target Cardiac Tissue
Straight to the Heart: T Cells That Specifically Target Cardiac Tissue
Stefanie Dimmeler Correspondence to: Stefanie Dimmeler, PhD, Institute for Cardiovascular Regeneration, Centre of Molecula...
Late-Breaking Science Abstracts and Featured Science Abstracts From the American Heart Association's Scientific Sessions 2022 and Late-Breaking Abstracts in Resuscitation Science From the Resuscitation Science Symposium 2022
© American Heart Association, Inc. All rights reserved. Unauthorized ...
Shortness of Breath and Near Syncope During Exertion in a Child: When–Patients–Worry Syndrome
S. Chandra Bose Reddy Correspondence to: S. Chandra Bose Reddy, MD, Children’s Hospital of Los Angeles, 4650 Sunset Boulev...
Risk of Heart Failure in Congenital Heart Disease: A Nationwide Register-based Cohort Study
Maria Fedchenko Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of ...
Effect of Intensive Blood Pressure Control on Troponin and Natriuretic Peptide Levels: Findings From SPRINT
BACKGROUND: Given the important role of cardiac injury and neurohormonal activation in the pathways leading from hypertens...
Prospective Association of Daily Steps With Cardiovascular Disease: A Harmonized Meta-Analysis
BACKGROUND: Taking fewer than the widely promoted “10 000 steps per day” has recently been associated with lower risk of a...
Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization
BACKGROUND: Brugada syndrome (BrS) is an inherited arrhythmia syndrome caused by loss-of-function variants in the cardiac ...
Challenging the Hemodynamic Hypothesis in Heart Failure With Preserved Ejection Fraction: Is Exercise Capacity Limited by Elevated Pulmonary Capillary Wedge Pressure?
BACKGROUND: Exercise intolerance is a defining characteristic of heart failure with preserved ejection fraction (HFpEF). A...
Coronary Artery Lesion Lipid Content and Plaque Burden in Diabetic and Nondiabetic Patients: PROSPECT II
BACKGROUND: Patients with diabetes have increased rates of major adverse cardiac events (MACEs). We hypothesized that this...
Stages of Valvular Heart Disease Among Older Adults in the Community: The Atherosclerosis Risk in Communities Study
BACKGROUND: Limited data exist on American College of Cardiology/American Heart Association valvular heart disease (VHD) s...
Randomized Trials Fit for the 21st Century: A Joint Opinion From the European Society of Cardiology, American Heart Association, American College of Cardiology, and the World Heart Federation
Louise Bowman Correspondence to: Louise Bowman, Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Dep...
Eliminating Senescent Cells Can Promote Pulmonary Hypertension Development and Progression
BACKGROUND: Senescent cells (SCs) are involved in proliferative disorders, but their role in pulmonary hypertension remain...
The Effect of Lymphangiogenesis in Transplant Arteriosclerosis
BACKGROUND: Transplant arteriosclerosis is a major complication in long-term survivors of heart transplantation. Increased...
Novel Cardiokine GDF3 Predicts Adverse Fibrotic Remodeling After Myocardial Infarction
BACKGROUND: Myocardial infarction (MI) induces a repair response that ultimately generates a stable fibrotic scar. Althoug...
GLP-1 Receptor Agonists for the Reduction of Atherosclerotic Cardiovascular Risk in Patients With Type 2 Diabetes
GLP-1 Receptor Agonists for the Reduction of Atherosclerotic Cardiovascular Risk in Patients With Type 2 Diabetes
Patients with type 2 diabetes are at high risk for development of cardiovascular disease, including myocardial infarction,...
Letter by Xie and Hou Regarding Article, “Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity”
"Letter by Xie and Hou Regarding Article, “Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote ...
Response by Sedej and Abdellatif to Letter Regarding Article, “Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity”
Mahmoud Abdellatif https://orcid.org/0000-0002-5042-9054 Department of Cardiology, Medical University of Graz, Austria (S...
Kidney Hemodynamic Effects of Angiotensin Receptor Blockade, Sodium-Glucose Cotransporter-2 Inhibition Alone, and Their Combination: A Crossover Randomized Trial in People With Type 2 Diabetes
Kidney Hemodynamic Effects of Angiotensin Receptor Blockade, Sodium-Glucose Cotransporter-2 Inhibition Alone, and Their Combination: A Crossover Randomized Trial in People With Type 2 Diabetes
Daniël H. van Raalte Correspondence to: Daniël H. van Raalte, MD, Amsterdam University Medical Centers, Location VUMC, De ...
Coronary Vasospasm With Pulse Field Ablation: Primum Non Nocere
N.A. Mark Estes Correspondence to: N.A. Mark Estes, MD, The Heart and Vascular Institute, University of Pittsburgh Medical...
Direct Reprogramming Improves Cardiac Function and Reverses Fibrosis in Chronic Myocardial Infarction
BACKGROUND: Because adult cardiomyocytes have little regenerative capacity, resident cardiac fibroblasts (CFs) synthesize ...
Associations Between Extreme Temperatures and Cardiovascular Cause-Specific Mortality: Results From 27 Countries
Background: Cardiovascular disease is the leading cause of death worldwide. Existing studies on the association between te...
Management of Acute Coronary Syndrome in the Older Adult Population: A Scientific Statement From the American Heart Association
Diagnostic and therapeutic advances during the past decades have substantially improved health outcomes for patients with ...
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