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Ectopic expression of murine CD163 enables cell-culture isolation of lactate dehydrogenase-elevating virus 63 years after its discovery
Ectopic expression of murine CD163 enables cell-culture isolation of lactate dehydrogenase-elevating virus 63 years after its discovery
ABSTRACTArteriviruses are RNA viruses related to coronaviruses but have not yet been associated with human infection. A mu...
Palmitoylation of the hemagglutinin of influenza B virus by ER-localized DHHC enzymes 1, 2, 4, and 6 is required for efficient virus replication
Palmitoylation of the hemagglutinin of influenza B virus by ER-localized DHHC enzymes 1, 2, 4, and 6 is required for efficient virus replication
ABSTRACT Covalent attachment of the fatty acid palmitate or stearate to the cytoplasmic domain of viral glycoproteins is o...
A viral protein targets mitochondria and chloroplasts by subverting general import pathways and specific receptors
A viral protein targets mitochondria and chloroplasts by subverting general import pathways and specific receptors
ABSTRACT Dual targeting is a relatively little explored phenomenon by which some proteins are transported to two different...
Chimeric virus-like particles of human norovirus constructed by structure-guided epitope grafting elicit cross-reactive immunity against both GI.1 and GII.4 genotypes
Chimeric virus-like particles of human norovirus constructed by structure-guided epitope grafting elicit cross-reactive immunity against both GI.1 and GII.4 genotypes
ABSTRACT Human norovirus (HuNoV) is the main cause of acute non-bacterial gastroenteritis worldwide. There is no vaccine c...
A single polymorphic residue in humans underlies species-specific restriction of HSV-1 by the antiviral protein MxB
A single polymorphic residue in humans underlies species-specific restriction of HSV-1 by the antiviral protein MxB
ABSTRACT Myxovirus resistance proteins A and B (MxA and MxB) are interferon-induced proteins that exert antiviral activity...
Neutralizing antibodies with neurotropic factor treatment maintain neurodevelopmental gene expression upon exposure to human cytomegalovirus
Neutralizing antibodies with neurotropic factor treatment maintain neurodevelopmental gene expression upon exposure to human cytomegalovirus
ABSTRACT Human cytomegalovirus (HCMV) is a beta herpesvirus that causes severe congenital birth defects including microcep...
Insulin-mediated endothelin signaling is antiviral during West Nile virus infection
Insulin-mediated endothelin signaling is antiviral during West Nile virus infection
ABSTRACT West Nile virus (WNV) is the most prevalent mosquito-borne virus in the United States with approximately 2,000 ca...
N-terminal domain of classical swine fever virus Npro induces proteasomal degradation of specificity protein 1 with reduced HDAC1 expression to evade from innate immune responses
N-terminal domain of classical swine fever virus Npro induces proteasomal degradation of specificity protein 1 with reduced HDAC1 expression to evade from innate immune responses
ABSTRACTClassical swine fever virus (CSFV) poses a major threat to the pig industry. The mechanisms that CSFV uses to evad...
Multiple mutations of SARS-CoV-2 Omicron BA.2 variant orchestrate its virological characteristics
Multiple mutations of SARS-CoV-2 Omicron BA.2 variant orchestrate its virological characteristics
ABSTRACT Previous studies on the Omicron BA.2 variant suggested that the virological characteristics of BA.2 are determine...
Kaposi’s sarcoma-associated herpesvirus glycoprotein K8.1 is critical for infection in a cell-specific manner and functions at the attachment step on keratinocytes
Kaposi’s sarcoma-associated herpesvirus glycoprotein K8.1 is critical for infection in a cell-specific manner and functions at the attachment step on keratinocytes
ABSTRACTKaposi’s sarcoma-associated herpesvirus (KSHV) is associated with Kaposi’s sarcoma and B cell malignancies. K8.1, ...
Tryptophan-based motifs in the LLP3 region of the HIV-1 envelope glycoprotein cytoplasmic tail direct trafficking to the endosomal recycling compartment and mediate particle incorporation
Tryptophan-based motifs in the LLP3 region of the HIV-1 envelope glycoprotein cytoplasmic tail direct trafficking to the endosomal recycling compartment and mediate particle incorporation
ABSTRACT The HIV-1 envelope glycoprotein complex (Env) is incorporated into developing particles at the plasma membrane (P...
Ubiquitin E3 ligase SPOP is a host negative regulator of enterovirus 71-encoded 2A protease
Ubiquitin E3 ligase SPOP is a host negative regulator of enterovirus 71-encoded 2A protease
ABSTRACT The 2A protease (2Apro) encoded by enterovirus 71 (EV71) serves as an accessory protein with significant involvem...
Deletion of the gene for the African swine fever virus BCL-2 family member A179L increases virus uptake and apoptosis but decreases virus spread in macrophages and reduces virulence in pigs
Deletion of the gene for the African swine fever virus BCL-2 family member A179L increases virus uptake and apoptosis but decreases virus spread in macrophages and reduces virulence in pigs
ABSTRACT The African swine fever virus (ASFV) encodes inhibitors of innate immune responses, including type I interferon a...
Correction for Tejera-Hernández et al., “Mouse Adenovirus Type 1 E4orf6 Induces PKR Degradation”
Correction for Tejera-Hernández et al., “Mouse Adenovirus Type 1 E4orf6 Induces PKR Degradation”
American Society for Microbiology ("ASM") is committed to maintaining your confidence and trust with respect to the inform...
Corrected and republished from: “VP4 Is a Determinant of Alpha-Defensin Modulation of Rotaviral Infection”
Corrected and republished from: “VP4 Is a Determinant of Alpha-Defensin Modulation of Rotaviral Infection”
ABSTRACT Fecal-oral pathogens encounter constitutively expressed enteric alpha-defensins in the intestine during replicati...
Erratum for Bach et al., “Regulation of VP30-Dependent Transcription by RNA Sequence and Structure in the Genomic Ebola Virus Promoter”
Erratum for Bach et al., “Regulation of VP30-Dependent Transcription by RNA Sequence and Structure in the Genomic Ebola Virus Promoter”
American Society for Microbiology ("ASM") is committed to maintaining your confidence and trust with respect to the inform...
Correction for Hu et al., “VP4 Is a Determinant of Alpha-Defensin Modulation of Rotaviral Infection”
Correction for Hu et al., “VP4 Is a Determinant of Alpha-Defensin Modulation of Rotaviral Infection”
American Society for Microbiology ("ASM") is committed to maintaining your confidence and trust with respect to the inform...
Activation of AIM2 by hepatitis B virus results in antiviral immunity that suppresses hepatitis C virus during coinfection
Activation of AIM2 by hepatitis B virus results in antiviral immunity that suppresses hepatitis C virus during coinfection
ABSTRACT Hepatitis B virus (HBV) infection in immunocompetent adults is mostly self-limiting, whereas Hepatitis C virus (H...
Extragenic suppression of an HSV-1 UL34 nuclear egress mutant reveals role for pUS9 as an inhibitor of epithelial cell-to-cell spread
Extragenic suppression of an HSV-1 UL34 nuclear egress mutant reveals role for pUS9 as an inhibitor of epithelial cell-to-cell spread
ABSTRACT The herpes simplex virus pUL34 component of the nuclear egress complex functions in both nuclear egress and cell-...
HCMV UL8 interaction with β-catenin and DVL2 regulates viral reactivation in CD34+ hematopoietic progenitor cells
HCMV UL8 interaction with β-catenin and DVL2 regulates viral reactivation in CD34+ hematopoietic progenitor cells
ABSTRACT Human cytomegalovirus (HCMV) is a species-specific virus that establishes a persistent/latent infection in CD34+ ...
Soluble CD4 and low molecular weight CD4-mimetic compounds sensitize cells to be killed by anti-HIV cytotoxic immunoconjugates
Soluble CD4 and low molecular weight CD4-mimetic compounds sensitize cells to be killed by anti-HIV cytotoxic immunoconjugates
ABSTRACT The reservoir of HIV-infected cells that persist in the face of effective anti-retroviral therapy (ART) is the ba...
EGR1 functions as a new host restriction factor for SARS-CoV-2 to inhibit virus replication through the E3 ubiquitin ligase MARCH8
EGR1 functions as a new host restriction factor for SARS-CoV-2 to inhibit virus replication through the E3 ubiquitin ligase MARCH8
ABSTRACT Coronavirus disease 2019, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to an u...
N-linked glycoproteins and host proteases are involved in swine acute diarrhea syndrome coronavirus entry
N-linked glycoproteins and host proteases are involved in swine acute diarrhea syndrome coronavirus entry
ABSTRACTSwine acute diarrhea syndrome coronavirus (SADS-CoV) is highly pathogenic to piglets and poses a major threat to t...
Single-molecule-binding studies of antivirals targeting the hepatitis C virus core protein
Single-molecule-binding studies of antivirals targeting the hepatitis C virus core protein
ABSTRACT The hepatitis C virus (HCV) core protein (HCVcp) is the most highly conserved protein encoded by the HCV genome, ...
Interferon regulatory factor 7 modulates virus clearance and immune responses to alphavirus encephalomyelitis
Interferon regulatory factor 7 modulates virus clearance and immune responses to alphavirus encephalomyelitis
ABSTRACT Central nervous system (CNS) infection with Sindbis virus (SINV), the prototypic alphavirus, results in encephalo...
Transcriptome screening identifies TIPARP as an antiviral host factor against the Getah virus
Transcriptome screening identifies TIPARP as an antiviral host factor against the Getah virus
ABSTRACT Alphaviruses are emerging and re-emerging viruses that cause severe disease and threaten public health worldwide....
Signal peptide and N-glycosylation of N-terminal-CD2v determine the hemadsorption of African swine fever virus
Signal peptide and N-glycosylation of N-terminal-CD2v determine the hemadsorption of African swine fever virus
ABSTRACTAfrican swine fever virus (ASFV) is the cause of African swine fever (ASF), a devastating disease that affects dom...
Electron microscopy mapping of the DNA-binding sites of monomeric, dimeric, and multimeric KSHV RTA protein
Electron microscopy mapping of the DNA-binding sites of monomeric, dimeric, and multimeric KSHV RTA protein
ABSTRACT Molecular interactions between viral DNA and viral-encoded protein are a prerequisite for successful herpesvirus ...
Molecular characterization of the 2022 Sudan virus disease outbreak in Uganda
Molecular characterization of the 2022 Sudan virus disease outbreak in Uganda
ABSTRACT Uganda experienced five Ebola disease outbreaks caused by Bundibugyo virus (n = 1) and Sudan virus (SUDV) (n = 4)...
Herpes simplex virus 1 immediate early transcription initiation, pause-release, elongation, and termination in the presence and absence of ICP4
Herpes simplex virus 1 immediate early transcription initiation, pause-release, elongation, and termination in the presence and absence of ICP4
ABSTRACT Herpes simplex virus 1 (HSV-1) transcription is tightly regulated in a temporal cascade, utilizing cellular RNA p...
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