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Born too soon: lifelong kidney risks and the importance of early intervention
Premature birth and low birth weight disrupt kidney development substantially, which leads to an increased risk of acute k...
Insights into the burden of CKDu
Chronic kidney disease of undetermined cause (CKDu) is a progressive form of chronic kidney disease (CKD) that is not asso...
Loss of B cell protection in uraemic kidney disease
Loss of B cell protection in uraemic kidney disease
The mechanisms that drive impaired immunity in people with kidney disease remain unclear. A study by Partha Biswas and col...
Risk-directed management of chronic kidney disease
Risk-directed management of chronic kidney disease
The timely and rational institution of therapy is a key step towards reducing the global burden of chronic kidney disease ...
Artificial intelligence approaches to enable early detection of CKD
The late diagnosis of chronic kidney disease (CKD) is a global problem that limits the opportunity to initiate disease-mod...
Publisher Correction: Clinical practice recommendations for the diagnosis and management of X-linked hypophosphataemia
Department of Paediatric Kidney, Liver, Metabolic and Neurological Diseases, Hannover Medical, School, Hannover, GermanyDi...
Advances and challenges in kidney fibrosis therapeutics
Advances and challenges in kidney fibrosis therapeutics
Chronic kidney disease (CKD) is a major global health burden that affects more than 10% of the adult population. Current t...
Progress towards improving blood pressure control
Progress towards improving blood pressure control
Despite the availability of effective therapies, the majority of patients with hypertension have poor blood pressure contr...
Consideration of sex differences is necessary to achieve health equity
Improved understanding of the impact of sex and gender-related factors on human health and disease and the inclusion of pe...
Targeted identification of risk and treatment of diabetic kidney disease
Basic discovery and clinical trials in diabetic kidney disease (DKD) have continued to be reported in 2023 despite the dis...
Differences in the epidemiology, management and outcomes of kidney disease in men and women
Differences in the epidemiology, management and outcomes of kidney disease in men and women
Improved understanding of differences in kidney disease epidemiology, management and outcomes in men and women could help ...
Mechanisms and consequences of sex differences in immune responses
Mechanisms and consequences of sex differences in immune responses
Biological sex differences refer to differences between males and females caused by the sex chromosome complement (that is...
Author Correction: The immunoregulatory roles of non-haematopoietic cells in the kidney
Authors and AffiliationsDepartment of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USAGeorge C. Tsokos, Afr...
Renoprotective effects of sparsentan: clinical trial evidence in IgA nephropathy and FSGS
Renoprotective effects of sparsentan: clinical trial evidence in IgA nephropathy and FSGS
In early 2023, the dual endothelin–angiotensin receptor antagonist sparsentan became the first non-immunosuppressive thera...
Targeting APRIL to slow progression of IgA nephropathy
Targeting APRIL to slow progression of IgA nephropathy
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The immunoregulatory roles of non-haematopoietic cells in the kidney
The immunoregulatory roles of non-haematopoietic cells in the kidney
The deposition of immune complexes, activation of complement and infiltration of the kidney by cells of the adaptive and i...
Kidney xenotransplantation edges closer to the clinic
Kidney xenotransplantation edges closer to the clinic
The demand for kidney transplants is far from met by human donors — a problem that may be solved by the clinical tra...
Equitable access to kidney transplants for Aboriginal and Torres Strait Islander people in Australia
Equitable access to kidney transplants for Aboriginal and Torres Strait Islander people in Australia
First Nations peoples in Australia face systemic inequities in access to kidney transplantation. The National Indigenous&a...
Transport and barrier mechanisms that regulate ciliary compartmentalization and ciliopathies
Transport and barrier mechanisms that regulate ciliary compartmentalization and ciliopathies
Primary cilia act as cell surface antennae, coordinating cellular responses to sensory inputs and signalling molecules tha...
Taking kidney temperatures to detect rejection
Taking kidney temperatures to detect rejection
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A new pathway links iron sensing with histone demethylation and regulation of mTORC1 activity
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Clonal haematopoiesis, ageing and kidney disease
Clonal haematopoiesis, ageing and kidney disease
Clonal haematopoiesis of indeterminate potential (CHIP) is a preclinical condition wherein a sizeable proportion of an ind...
Sex differences in energy metabolism: natural selection, mechanisms and consequences
Sex differences in energy metabolism: natural selection, mechanisms and consequences
Metabolic homeostasis operates differently in men and women. This sex asymmetry is the result of evolutionary adaptations ...
Publisher Correction: Drosophila melanogaster: a simple genetic model of kidney structure, function and disease
In the version of the article initially published, two references were omitted that should have been cited in Table 3. In ...
Chronic cardiovascular–kidney disorder: a new conceptual framework
Chronic cardiovascular–kidney disorder: a new conceptual framework
The current nomenclature for cardiorenal syndrome is problematic owing to its chronological approach and the systemic natu...
TRPM channels in health and disease
TRPM channels in health and disease
Different cell channels and transporters tightly regulate cytoplasmic levels and the intraorganelle distribution of cation...
Embryo complementation to generate a humanized mesonephros in pigs
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MSC therapy for diabetic kidney disease and nephrotic syndrome
MSC therapy for diabetic kidney disease and nephrotic syndrome
New clinical studies suggest that mesenchymal stem cell (MSC) therapy can have positive clinical effects, potentially via ...
Biomolecular condensates in kidney physiology and disease
Biomolecular condensates in kidney physiology and disease
The regulation and preservation of distinct intracellular and extracellular solute microenvironments is crucial for the ma...
The immune response to pig-to-human kidney xenografts
The immune response to pig-to-human kidney xenografts
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