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BeWo exomeres are enriched for bioactive extracellular placenta-specific C19MC miRNAs
BeWo exomeres are enriched for bioactive extracellular placenta-specific C19MC miRNAs
Most, if not all, types of cells secrete extracellular vesicles (EVs) for intercellular communication (Théry et al. 2009)....
The Role of First Trimester Serum Inflammatory Indexes (NLR, PLR, MLR, SII, SIRI, and PIV) and the β-hCG to PAPP-A Ratio in Predicting Preeclampsia
The Role of First Trimester Serum Inflammatory Indexes (NLR, PLR, MLR, SII, SIRI, and PIV) and the β-hCG to PAPP-A Ratio in Predicting Preeclampsia
ObjectiveThe aim of this study was to investigate the predictive value of inflammation parameters and indices measured in ...
Placentation and complications of ART pregnancy. An update on the different possible etiopathogenic mechanisms involved in the development of obstetric complications.
Placentation and complications of ART pregnancy. An update on the different possible etiopathogenic mechanisms involved in the development of obstetric complications.
IntroductionInfertile couples’ percentage is increasing all over the world, especially in Italy, with high number of child...
Cytoplasmic and Nuclear DROSHA in Human Villous Trophoblasts
Cytoplasmic and Nuclear DROSHA in Human Villous Trophoblasts
In the human placenta, antiviral immune responses must be strictly regulated because they could disrupt the mechanisms tha...
The Role of the Endometrial Microbiome in Embryo Implantation and Recurrent Implantation Failure
The Role of the Endometrial Microbiome in Embryo Implantation and Recurrent Implantation Failure
The expected prevalence of recurrent implantation failures (RIF) is reported to be 15%. Addressing infertility in individu...
Classification of preeclampsia according to molecular clusters with the goal of achieving personalized prevention
Classification of preeclampsia according to molecular clusters with the goal of achieving personalized prevention
Extracellular matrix-related pre-eclampsiaLiquid biopsyMaternal anti-fetal rejection-type pre-eclampsiaMetabolic pre-eclam...
Expanding the role of chromosomal microarray analysis in the evaluation of recurrent pregnancy loss
Expanding the role of chromosomal microarray analysis in the evaluation of recurrent pregnancy loss
Recurrent pregnancy loss (RPL) affects up to 3% of reproductive age couples (Van Dijk et al., 2020). RPL is a stressor tha...
Moesin affects the plasma membrane expression and the immune checkpoint function of CD47 in human ovarian clear cell carcinoma
Moesin affects the plasma membrane expression and the immune checkpoint function of CD47 in human ovarian clear cell carcinoma
Epithelial ovarian cancer is one of the leading causes of death from gynecological malignancies worldwide, with a high rec...
Extra villous trophoblast-derived PDL1 can ameliorate macrophage inflammation and promote immune adaptation associated with preeclampsia
Extra villous trophoblast-derived PDL1 can ameliorate macrophage inflammation and promote immune adaptation associated with preeclampsia
Severe preeclampsia (sPE) is a pregnancy-specific disease that affects 2–8% of all pregnancies (Jimmy Espinoza et al., 202...
The effect of seminal pathogens on standard semen parameters, sperm kinematics and seminal inflammatory markers
The effect of seminal pathogens on standard semen parameters, sperm kinematics and seminal inflammatory markers
The presence of pathogenic bacteria in semen is a main criterion for male accessory gland infection (Rowe et al., 2000) an...
Exploring Lactoferrin as a novel marker for disease pathology and ferroptosis regulation in gestational diabetes
Exploring Lactoferrin as a novel marker for disease pathology and ferroptosis regulation in gestational diabetes
Gestational diabetes mellitus (GDM) is a manifestation of glucose intolerance first diagnosed during pregnancy (gestation)...
Frequent expression of CD45RO memory T cell marker as well as low to high expression of PD-1 and PD-L1 inhibitory molecules in seminoma and dysgerminoma
Frequent expression of CD45RO memory T cell marker as well as low to high expression of PD-1 and PD-L1 inhibitory molecules in seminoma and dysgerminoma
Germ cell tumors are diverse and uncommon malignancies originating from germ cells in gonads or extragonadal sites. The go...
Effects of calcitriol upon TGF-βs and their receptors in trophoblast cells
Effects of calcitriol upon TGF-βs and their receptors in trophoblast cells
The human placenta expresses a wide spectrum of hormones, cytokines, and growth factors involved in blastocyte implantatio...
NLRP3 inflammasome pathway, the hidden balance in pregnancy: A comprehensive review
NLRP3 inflammasome pathway, the hidden balance in pregnancy: A comprehensive review
It is essential that post-fertilization embryo development, implantation, and decidualization take place properly in mamma...
Role of macrophage colony stimulating factor and interferon regulatory factor 7 in modulating the immune profile of mouse testicular macrophages
Role of macrophage colony stimulating factor and interferon regulatory factor 7 in modulating the immune profile of mouse testicular macrophages
Tissue resident macrophages are the sentinel cells of most organs and play an essential role in normal organ homeostasis, ...
L-ergothioneine reduces mitochondrial-driven NLRP3 activation in gestational diabetes mellitus
L-ergothioneine reduces mitochondrial-driven NLRP3 activation in gestational diabetes mellitus
AbbreviationsASCapoptosis-associated speck-like protein containing a CARDCARDcaspase activation and recruitment domainCf-m...
What’s with the boys? Lower birth weight in boys from HPA-1a alloimmunized pregnancies – New insights from a large prospective screening study in Poland
What’s with the boys? Lower birth weight in boys from HPA-1a alloimmunized pregnancies – New insights from a large prospective screening study in Poland
Fetomaternal incompatibility in human platelet antigens (HPAs) can cause maternal alloimmunization, which in turn may lead...
Title: Repeated implantation failure is associated with increased Th17/Treg cell ratio, during the secretory phase of the human endometrium
Title: Repeated implantation failure is associated with increased Th17/Treg cell ratio, during the secretory phase of the human endometrium
Implantation failure is considered nowadays the most important limiting factor in assisted reproduction (Cross et al., 199...
Corrigendum to “Actually laboratory parameters for prognosis of fertility in varicocele patients” J. Reprod. Immunol. 159C (2023) 104058
Corrigendum to “Actually laboratory parameters for prognosis of fertility in varicocele patients” J. Reprod. Immunol. 159C (2023) 104058
Volume 160, December 2023, 104165Author links open overlay panelNakonechnyi Yozef a, Nakonechnyi Andrey b, Fraczek Monika ...
Sleep deprivation during pregnancy leads to poor fetal outcomes in Sprague–Dawley rats
Sleep deprivation during pregnancy leads to poor fetal outcomes in Sprague–Dawley rats
Volume 160, December 2023, 104166Author links open overlay panel, , , , , , Highlights•Sleep deprivation during pregnancy ...
Increasing expression of STING by ERα antagonizes LCN2 downregulation during chronic endometritis
Increasing expression of STING by ERα antagonizes LCN2 downregulation during chronic endometritis
Chronic endometritis (CE) is a persistent inflammatory disease of local endometrium caused by an abnormal endometrial micr...
Ovarian follicle transcriptome dynamics reveals enrichment of immune system process during transition from small to large follicles in cyclic Indian Ghoongroo pigs
Ovarian follicle transcriptome dynamics reveals enrichment of immune system process during transition from small to large follicles in cyclic Indian Ghoongroo pigs
Ovarian follicles constitute the functional unit of ovaries and supports the development and maturation of oocytes. They a...
HNRNPC mediated m6A methylation of 5-methyltetrahydrofolate-homocysteine methyltransferase and involved in the occurrence of RSA
HNRNPC mediated m6A methylation of 5-methyltetrahydrofolate-homocysteine methyltransferase and involved in the occurrence of RSA
N6-methyladenosine (m6A) methylated modification as the most prevalent and abundant epigenetic modification in eukaryote m...
Investigations of leukocyte and inflammatory markers in pregnancies complicated by preeclampsia
Investigations of leukocyte and inflammatory markers in pregnancies complicated by preeclampsia
Preeclampsia, a multisystem pregnancy complication, affects about 2-8% of all pregnant women worldwide and is one of the l...
Assessing the endometrium: an update on current and potential novel biomarkers of receptivity
Assessing the endometrium: an update on current and potential novel biomarkers of receptivity
Available online 7 October 2023, 104162Author links open overlay panel, AbstractA cyclical evolvement of the endometrium i...
HNRNPC mediated m6A methylation of 5-Methyltetrahydrofolate-homocysteine methyltransferase and involved in the occurrence of recurrent spontaneous abortion
HNRNPC mediated m6A methylation of 5-Methyltetrahydrofolate-homocysteine methyltransferase and involved in the occurrence of recurrent spontaneous abortion
N6-methyladenosine (m6A) methylated modification as the most prevalent and abundant epigenetic modification in eukaryote m...
Placenta and maternal endothelium during preeclampsia: Disruption of the glycocalyx explains increased inositol phosphoglycans and angiogenic factors in maternal blood.
Placenta and maternal endothelium during preeclampsia: Disruption of the glycocalyx explains increased inositol phosphoglycans and angiogenic factors in maternal blood.
Preeclampsia is a severe complication of human pregnancy that contributes significantly to maternal and perinatal mortalit...
Reduced expression of miR-221 is associated with the pro-apoptotic pathways in spermatozoa of oligospermia men
Reduced expression of miR-221 is associated with the pro-apoptotic pathways in spermatozoa of oligospermia men
Oligospermia and asthenozoospermia, both frequent, can lead to male infertility. Oligospermia might be viewed as a milder ...
Calcineurin inhibitors in the management of recurrent miscarriage and recurrent implantation failure: Systematic review and meta-analysis
Calcineurin inhibitors in the management of recurrent miscarriage and recurrent implantation failure: Systematic review and meta-analysis
Traditionally, the World Health Organization (WHO) defines recurrent miscarriage (RM) as the occurrence of three or more c...
Regulatory role of human endometrial gland secretome on macrophage differentiation
Regulatory role of human endometrial gland secretome on macrophage differentiation
Successful pregnancy depends on the mother's immune tolerance towards the semi-allogeneic fetus, primarily facilitated by ...
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