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ChatGPT for scientific writing — The coexistence of opportunities and challenges
ChatGPT for scientific writing — The coexistence of opportunities and challenges
Volume 44, January 2024, Pages A1-A3Author links open overlay panelLiangbin Zhou 1, Alex Chao Wu 2, Péter Hegyi, Chunyi We...
Advances in osteoarthritis research: From diagnosis, treatment to mechanism studies
Advances in osteoarthritis research: From diagnosis, treatment to mechanism studies
Volume 44, January 2024, Pages A4-A6Author links open overlay panelZhongyang Lv a b, Ziling Wang c d e, Di Chen c d, Dongq...
The association between anterior cruciate ligament degeneration and incident knee osteoarthritis: Data from the osteoarthritis initiative
The association between anterior cruciate ligament degeneration and incident knee osteoarthritis: Data from the osteoarthritis initiative
BackgroundThough anterior cruciate ligament (ACL) tear has been widely accepted as an important accelerator for knee osteo...
Daily low-intensity pulsed ultrasound stimulation mitigates joint degradation and pain in a post-traumatic osteoarthritis rat model
Daily low-intensity pulsed ultrasound stimulation mitigates joint degradation and pain in a post-traumatic osteoarthritis rat model
ObjectivesThe aim of this study was to investigate the effects of low-intensity pulsed ultrasound (LIPUS) in a post-trauma...
Elevated secretion of pro-collagen I-alpha and vascular endothelial growth factor as biomarkers of acetabular labrum degeneration and calcification in hip osteoarthritis: An explant study
Elevated secretion of pro-collagen I-alpha and vascular endothelial growth factor as biomarkers of acetabular labrum degeneration and calcification in hip osteoarthritis: An explant study
Volume 44, January 2024, Pages 19-25Author links open overlay panel, , , , , AbstractBackgroundHip osteoarthritis (OA) inv...
The silencing of NREP aggravates OA cartilage damage through the TGF-β1/Smad2/3 pathway in chondrocytes
The silencing of NREP aggravates OA cartilage damage through the TGF-β1/Smad2/3 pathway in chondrocytes
Volume 44, January 2024, Pages 26-34Author links open overlay panel, , , , , , , , AbstractBackgroundOsteoarthritis (OA) i...
TCF12 regulates the TGF-β/Smad2/3 signaling pathway to accelerate the progression of osteoarthritis by targeting CXCR4
TCF12 regulates the TGF-β/Smad2/3 signaling pathway to accelerate the progression of osteoarthritis by targeting CXCR4
Volume 44, January 2024, Pages 35-46Author links open overlay panel, , , , , , , , , , AbstractObjectiveOsteoarthritis (OA...
The IRF1/GBP5 axis promotes osteoarthritis progression by activating chondrocyte pyroptosis
The IRF1/GBP5 axis promotes osteoarthritis progression by activating chondrocyte pyroptosis
Volume 44, January 2024, Pages 47-59Author links open overlay panel, , , , , , , , , AbstractBackgroundOsteoarthritis (OA)...
JD-312 – A novel small molecule that facilitates cartilage repair and alleviates osteoarthritis progression
JD-312 – A novel small molecule that facilitates cartilage repair and alleviates osteoarthritis progression
Volume 44, January 2024, Pages 60-71Author links open overlay panel, , , , , , , , , , , , AbstractBackgroundThe chondroge...
Combination of a human articular cartilage-derived extracellular matrix scaffold and microfracture techniques for cartilage regeneration: A proof of concept in a sheep model
Combination of a human articular cartilage-derived extracellular matrix scaffold and microfracture techniques for cartilage regeneration: A proof of concept in a sheep model
BackgroundThe utilization of decellularized extracellular matrix has gained considerable attention across numerous areas i...
Targeting FGFR3 signaling and drug repurposing for the treatment of SLC26A2-related chondrodysplasia in mouse model
Targeting FGFR3 signaling and drug repurposing for the treatment of SLC26A2-related chondrodysplasia in mouse model
Volume 44, January 2024, Pages 88-101Author links open overlay panel, , , , , , , , , AbstractBackgroundMutations in Slc26...
Computational screening of biomarkers and potential drugs for arthrofibrosis based on combination of sequencing and large nature language model
Computational screening of biomarkers and potential drugs for arthrofibrosis based on combination of sequencing and large nature language model
Volume 44, January 2024, Pages 102-113Author links open overlay panel, , , , AbstractBackgroundArthrofibrosis (AF) is a fi...
XJB-5-131 protects chondrocytes from ferroptosis to alleviate osteoarthritis progression via restoring Pebp1 expression
XJB-5-131 protects chondrocytes from ferroptosis to alleviate osteoarthritis progression via restoring Pebp1 expression
Volume 44, January 2024, Pages 114-124Author links open overlay panel, , , , , , , , , , , , , , , , , AbstractBackgroundO...
G protein-coupled receptor 30 activation inhibits ferroptosis and protects chondrocytes against osteoarthritis
G protein-coupled receptor 30 activation inhibits ferroptosis and protects chondrocytes against osteoarthritis
BackgroundOsteoarthritis (OA) is the most common joint disease worldwide, but its cause remains unclear. Oestrogen protect...
Inhibition of PI3K/AKT signaling pathway prevents blood-induced heterotopic ossification of the injured tendon
Inhibition of PI3K/AKT signaling pathway prevents blood-induced heterotopic ossification of the injured tendon
ObjectiveIt is a common clinical phenomenon that blood infiltrates into the injured tendon caused by sports injuries, acci...
Implants coating strategies for antibacterial treatment in fracture and defect models: A systematic review of animal studies
Implants coating strategies for antibacterial treatment in fracture and defect models: A systematic review of animal studies
ObjectiveFracture-related infection (FRI) remains a major concern in orthopaedic trauma. Functionalizing implants with ant...
Intra-articular injection of platelet lysate-derived extracellular vesicles recovers from knee osteoarthritis in an in vivo rat model
Intra-articular injection of platelet lysate-derived extracellular vesicles recovers from knee osteoarthritis in an in vivo rat model
ObjectiveMSCs and Platelet-Rich Plasma are the main focus in the study of new regenerative treatments aimed to reverse Ost...
Shock wave assisted intracellular delivery of antibiotics against bone infection with Staphylococcus aureus via P2X7 receptors
Shock wave assisted intracellular delivery of antibiotics against bone infection with Staphylococcus aureus via P2X7 receptors
BackgroundTreatment of chronic osteomyelitis (bone infection) remains a clinical challenge; in particular, it requires enh...
Pip5k1c expression in osteocytes regulates bone remodeling in mice
Pip5k1c expression in osteocytes regulates bone remodeling in mice
Volume 45, March 2024, Pages 36-47Author links open overlay panel, , , , , , , , , , AbstractResearch backgroundThe role o...
Melatonin alleviates oxidative stress-induced injury to nucleus pulposus-derived mesenchymal stem cells through activating PI3K/Akt pathway
Melatonin alleviates oxidative stress-induced injury to nucleus pulposus-derived mesenchymal stem cells through activating PI3K/Akt pathway
BackgroundThe changes in the microenvironment of degenerative intervertebral discs cause oxidative stress injury and exces...
Choosing the right animal model for osteomyelitis research: Considerations and challenges
Choosing the right animal model for osteomyelitis research: Considerations and challenges
Osteomyelitis is a debilitating bone disorder characterized by an inflammatory process involving the bone marrow, bone cor...
Recent advances in understanding molecular mechanisms and novel strategies for the treatment of osteoarthritis and other diseases related with cartilage defects
Recent advances in understanding molecular mechanisms and novel strategies for the treatment of osteoarthritis and other diseases related with cartilage defects
Available online 18 November 2023Author links open overlay panelJiawei Li a b, Dongquan Shi a, Di Chen c dShow moreRecomme...
Muscle-bone crosstalk via endocrine signals and potential targets for osteosarcopenia-related fracture
Muscle-bone crosstalk via endocrine signals and potential targets for osteosarcopenia-related fracture
Volume 43, November 2023, Pages 36-46Author links open overlay panel, , , , , , , , , AbstractBackgroundOsteosarcopenia is...
Silicone rubber sealed channel induced self-healing of large bone defects: Where is the limit of self-healing of bone?
Silicone rubber sealed channel induced self-healing of large bone defects: Where is the limit of self-healing of bone?
Volume 43, November 2023, Pages 21-35Author links open overlay panel, , , , , , AbstractBackgroundLarge defects of long tu...
COVID-19 hip fracture outcomes: The role of Ct values and D-dimer levels?
COVID-19 hip fracture outcomes: The role of Ct values and D-dimer levels?
Volume 43, November 2023, Pages 14-20Author links open overlay panel, , , , , , , , , AbstractIntroductionThe COVID-19 pan...
A systematic investigation of the effects of TGF-β3 and mechanical stimulation on tenogenic differentiation of mesenchymal stromal cells in a poly(ethylene glycol)/gelatin-based hydrogel
A systematic investigation of the effects of TGF-β3 and mechanical stimulation on tenogenic differentiation of mesenchymal stromal cells in a poly(ethylene glycol)/gelatin-based hydrogel
BackgroundHigh post-surgical failure rates following tendon injury generate high medical costs and poor patient recovery. ...
Chronic pain after spine surgery: Insights into pathogenesis, new treatment, and preventive therapy
Chronic pain after spine surgery: Insights into pathogenesis, new treatment, and preventive therapy
KeywordsAnimal modelsChronic pain after spine surgeryFailed back surgery syndromeLow back painPeripheral nervous systemSen...
Efficacy and safety of unilateral tibial cortex transverse transport on bilateral diabetic foot ulcers: A propensity score matching study
Efficacy and safety of unilateral tibial cortex transverse transport on bilateral diabetic foot ulcers: A propensity score matching study
BackgroundTibial Cortex Transverse Transport (TTT) has been demonstrated to be an effective treatment for unilateral diabe...
Biomaterial-based scaffolds in promotion of cartilage regeneration: Recent advances and emerging applications
Biomaterial-based scaffolds in promotion of cartilage regeneration: Recent advances and emerging applications
Volume 41, July 2023, Pages 54-62Author links open overlay panel, , , , , , AbstractOsteoarthritis (OA) poses a significan...
Modulating design parameters to drive cell invasion into hydrogels for osteochondral tissue formation
Modulating design parameters to drive cell invasion into hydrogels for osteochondral tissue formation
Volume 41, July 2023, Pages 42-53Author links open overlay panel, , , , , , , , , , , , , AbstractBackgroundThe use of ace...
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