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Reconstruction of rabbit corneal epithelium using adipose and / or bone marrow stem cells
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Clodronate liposome-mediated macrophage depletion ameliorates iron overload-induced dry eye disease
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O-GlcNAcylation promotes astroglial-mesenchymal transition via the connexin43 pathway under high-glucose conditions
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Dimethyl fumarate alleviates Staphylococcus pseudintermedius-induced cell damage by inhibiting pyroptosis and bacterial virulence
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Mitf over-expression leads to microphthalmia and coloboma in Mitf-cre mice
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Role of m6A methyltransferase METTL3 in keratoconus pathogenesis
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Inhibition of matrix metalloproteases by a chemical cross-linker to halt the corneal degradation in keratoconus
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Taurine mechanism in preventing retinal cell damage from acute ocular hypertension through GTPBP3 regulation
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Testosterone promotes photoreceptor degeneration in the sodium iodate model
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Photobiomodulation inhibits retinal degeneration in diabetic mice through modulation of stem cell mobilization and gene expression
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Effects of atropine on choroidal hemodynamics and VEGFA and HIF-1α expression in form-deprivation myopia guinea pigs
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Protective effects of different exercise modalities on oxidative stress in animal models of high intraocular pressure and diabetes
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Proteomic analysis of effects of 1% atropine in myopia therapy in Guinea pigs
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The vectors went in two-by-two: Transduction efficiency and tolerability of dual and triple rAAV vector delivery following intravitreal injection for genome-editing applications
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Effect of the IL-6 trans-signaling pathway in the absence or presence of TGF-β2 on Schlemm's canal endothelial cells
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SP1/COL1A2/ZEB1 axis promotes TGF-β2-induced lens epithelial cell proliferation, migration, invasion and EMT process
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miR-151a-5p predicts severity of diabetic retinopathy and protects from retinal cell injury by inactivating MAPK signaling via DKK3
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Metabolomic and transcriptomic analysis reveals metabolic-immune interactions in choroid neovascularization
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Tear inflammatory cytokine profiles in orbital inflammatory disease
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PI3K signaling and lysyl oxidase is critical to corneal stroma fibrosis following mustard gas injury
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An enhanced model for environmental dry eye: Exploring pathological features and underlying factors
An enhanced model for environmental dry eye: Exploring pathological features and underlying factors
Dry eye is a prevalent ocular surface disease that significantly affects visual acuity and quality of life, with hundreds ...
The role of the JAK/STAT3 signaling pathway in acquired corneal diseases
The role of the JAK/STAT3 signaling pathway in acquired corneal diseases
The health of the cornea has always been of great concern in the field of ophthalmology. The cornea is a transparent fibro...
Verteporfin regulates corneal neovascularization through inhibition of YAP protein activation
Verteporfin regulates corneal neovascularization through inhibition of YAP protein activation
As a transparent and avascular tissue, cornea is one of the most important refractive structures of the eye. At present, a...
Impact of a 50bp insertion/deletion polymorphism of the superoxide dismutase-1 on oxidative stress status and risk of keratoconus
Impact of a 50bp insertion/deletion polymorphism of the superoxide dismutase-1 on oxidative stress status and risk of keratoconus
Keratoconus (KC), as the most common corneal ectasia, is a significant clinical issue, affecting individuals worldwide. It...
Visualization of choroidal vasculature in pigmented mouse eyes from experimental models of AMD
Visualization of choroidal vasculature in pigmented mouse eyes from experimental models of AMD
There is increasing evidence that alterations in the choroidal vasculature play a key role in the early pathogenesis of ag...
Trolox aids coenzyme Q10 in neuroprotection against NMDA induced damage via upregulation of VEGF in rat model of glutamate excitotoxicity
Trolox aids coenzyme Q10 in neuroprotection against NMDA induced damage via upregulation of VEGF in rat model of glutamate excitotoxicity
Due to excess in glutamate levels, overstimulation of the glutamate receptors occurs and causes toxicity to retinal neuron...
Short peptides derived from pigment epithelium-derived factor attenuate retinal ischemia reperfusion injury through inhibition of apoptosis and inflammatory response in rats
Short peptides derived from pigment epithelium-derived factor attenuate retinal ischemia reperfusion injury through inhibition of apoptosis and inflammatory response in rats
Ischemia reperfusion (IR) injury is usually induced by high intraocular pressure (IOP) and is a pathological hallmark asso...
Reduction of lens size in PAX6-related aniridia
Reduction of lens size in PAX6-related aniridia
Heterozygous mutation of PAX6 in humans leads to congenital aniridia (OMIM 106210) which is typified by congenital iris an...
Inhibition of Rho kinase (ROCK) impairs cytoskeletal contractility in human Müller glial cells without effects on cell viability, migration, and extracellular matrix production
Inhibition of Rho kinase (ROCK) impairs cytoskeletal contractility in human Müller glial cells without effects on cell viability, migration, and extracellular matrix production
The epiretinal membrane is a common pathological condition characterized by the formation of fibrocontractile tissue at th...
Mouse model of radiation retinopathy reveals vascular and neuronal injury
Mouse model of radiation retinopathy reveals vascular and neuronal injury
Brachytherapy using episcleral 125I seed-filled plaques is the standard treatment for uveal melanoma, the most common prim...
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