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Modulation of retinoid-X-receptors differentially regulates expression of apolipoprotein genes apoc1 and apoeb by zebrafish microglia
Microglia are resident leukocytes in the vertebrate central ner...
Serotonin: an overlooked regulator of endocytosis and endosomal sorting?
Phospohoinositide-3-kinase (PI3K) is activated directly by the G-protein subunit...
Redundant functions of the SLC5A transporters Rumpel, Bumpel, and Kumpel in ensheathing glial cells
Cells require a constant energy supply to function. Metabolic a...
Myotonic dystrophy type 1 embryonic stem cells show decreased myogenic potential, increased CpG methylation at the DMPK locus and RNA mis-splicing
Myotonic Dystrophy type 1 (DM1, OMIM# 160900) is caused by an e...
The matrix in focus: new directions in extracellular matrix research from the 2021 ASMB hybrid meeting
The extracellular matrix (ECM) is a remarkably complex assembly of hundreds of p...
First person – Natalí Delorme and Leonardo Zamora
First Person is a series of interviews with the first authors o...
Multiple neural bHLHs ensure the precision of a neuronal specification event in Caenorhabditis elegans
Animals display complex behaviors. This functional complexity is mirrored by the...
Dynamic shapes of the zygote and two-cell mouse and human
Author contributionsConceptualization: C.F.G., S.W., A.A., A.V.; Methodology: C.F.G., S.W., A.A., A.V., K.S.; Software: S....
First person – Yixing Wu and Ying Bai
First Person is a series of interviews with the first authors o...
Alterations in brain glycogen levels influence life-history traits and reduce the lifespan in female Drosophila melanogaster
One of the long-standing questions in biology is the factors determining the lif...
A new method to localise and quantify oxidative stress in live juvenile mussels
Probes to detect and quantify reactive oxygen species (ROS) are typically used i...
Palmitoylated small GTPase ARL15 is translocated within Golgi network during adipogenesis
3T3-L1 (ATCC, CL-173) or human white adipocyte (hWAT, provided by Prof. Yu-Hua T...
Modest sexual size dimorphism and allometric growth: a study based on growth and gonad development in the wolf spider Pardosa pseudoannulata (Araneae: Lycosidae)
Females and males of most animals differ dramatically in their ...
Cellular senescence limits translational readthrough
To prepare total cell extracts, cells were washed with 1X PBS containing 1X prot...
Arf6 is necessary for senseless expression in response to wingless signalling during Drosophila wing development
In order to determine the level at which Arf6 is required in Wg signal transduct...
Vitamin A cycle byproducts explain retinal damage and molecular changes thought to initiate retinal degeneration
Profiling of messenger RNA was done as previously described (Ma et al., 2011). W...
Regulation of NANOG and SOX2 expression by activin A and a canonical WNT agonist in bovine embryonic stem cells and blastocysts
Embryonic stem cells (ESC) derived from the inner cell mass (IC...
First person – Yao Xiao
First Person is a series of interviews with the first authors of a selection of ...
Crosstalk between basal extracellular matrix adhesion and building of apical architecture during morphogenesis
In many morphogenetic events in Drosophila and other organisms, non-centrosomal ...
First person – Jillian Josimovich
First Person is a series of interviews with the first authors of a selection of ...
Clutch may predict growth of hatchling Burmese pythons better than food availability or sex
Evolutionary trade-offs in the allocation of energy and resourc...
Temperature-induced reorganisation of Schistocephalus solidus (Cestoda) proteome during the transition to the warm-blooded host
During the rapid adaptation to a sharp increase in temperature ...
First person – Sepideh Fallah
First Person is a series of interviews with the first authors of a selection of ...
Src family kinases inhibit differentiation of intestinal epithelial cells through the Hippo effector YAP1
In the present study, mouse monoclonal anti-MUC2 (ab11197, 1/500 WB and 1/100 IF...
Early-career researchers: answering the most important scientific questions of our time
Although being a biologist is fascinating and important, it is also extremely challenging; for no-one is the challenge gre...
Interaction between Discs large and Pins/LGN/GPSM2: a comparison across species
Discs large (Dlg) is a multifunctional scaffolding protein (Noi...
Identification of a new allele of O-fucosyltransferase 1 involved in Drosophila intestinal stem cell regulation
Flies were maintained on standard media at 25°C. Crosses were raised at 18°C in ...
Aneuploidy facilitates dysplastic and tumorigenic phenotypes in the Drosophila gut
The dysplasia phenotypes observed upon EGFR or JAK-STAT manipulation are often p...
Patterns of variations in dorsal colouration of the Italian wall lizard Podarcis siculus
Colour variation in the Italian wall lizards was assessed in a three-step analysis (Sacchi et al., 2021). First, we genera...
GRASP55 restricts early-stage autophagy and regulates spatial organization of the early secretory network
Commercially available antibodies were used as follows; citations and validation...
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