Inadequate sleep increases stroke risk: evidence from a comprehensive meta-analysis of incidence and mortality

Cappuccio FP, Miller MA. Sleep and mortality: cause, consequence, or symptom? Sleep Med. 2013;14:587–8. https://doi.org/10.1016/j.sleep.2013.04.001.

Article  PubMed  Google Scholar 

Cappuccio FP, Miller MA. Are short bad sleep nights a hindrance to a healthy heart? Sleep. 2011;34:1457–8. https://doi.org/10.5665/sleep.1372.

Article  PubMed  PubMed Central  Google Scholar 

Cappuccio FP, D’Elia L, Strazzullo P, Miller MA. Sleep duration and all-cause mortality: a systematic review and meta-analysis of prospective studies. Sleep. 2010;33:585–92. https://doi.org/10.1093/sleep/33.5.585.

Article  PubMed  PubMed Central  Google Scholar 

Cappuccio FP, D’Elia L, Strazzullo P, Miller MA. Quantity and quality of sleep and incidence of type 2 diabetes: a systematic review and meta-analysis. Diabetes Care. 2010;33:414–20. https://doi.org/10.2337/dc09-1124.

Article  PubMed  Google Scholar 

Cappuccio FP, Cooper D, D’Elia L, Strazzullo P, Miller MA. Sleep duration predicts cardiovascular outcomes: a systematic review and meta-analysis of prospective studies. Eur Heart J. 2011;32:1484–92. https://doi.org/10.1093/eurheartj/ehr007.

Article  PubMed  Google Scholar 

Cappuccio FP, Stranges S, Kandala NB, Miller MA, Taggart FM, Kumari M, Ferrie JE, Shipley MJ, Brunner EJ, Marmot MG. Gender-specific associations of short sleep duration with prevalent and incident hypertension: the Whitehall II Study. Hypertension. 2007;50:693–700. https://doi.org/10.1161/HYPERTENSIONAHA.107.095471.

Article  CAS  PubMed  Google Scholar 

Ferrie JE, Shipley MJ, Cappuccio FP, Brunner E, Miller MA, Kumari M, Marmot MG. A prospective study of change in sleep duration: associations with mortality in the Whitehall II cohort. Sleep. 2007;30:1659–66. https://doi.org/10.1093/sleep/30.12.1659.

Article  PubMed  PubMed Central  Google Scholar 

Leng Y, Wainwright NW, Cappuccio FP, Surtees PG, Hayat S, Luben R, Brayne C, Khaw KT. Daytime napping and the risk of all-cause and cause-specific mortality: a 13-year follow-up of a British population. Am J Epidemiol. 2014;179:1115–24. https://doi.org/10.1093/aje/kwu036.

Article  PubMed  PubMed Central  Google Scholar 

Miller MA, Cappuccio FP. Biomarkers of cardiovascular risk in sleep-deprived people. J Hum Hypertens. 2013;27:583–8. https://doi.org/10.1038/jhh.2013.27.

Article  CAS  PubMed  Google Scholar 

Bubu OM, Brannick M, Mortimer J, Umasabor-Bubu O, Sebastiao YV, Wen Y, Schwartz S, Borenstein AR, Wu Y, Morgan D, Anderson WM. Sleep, Cognitive impairment, and Alzheimer's disease: a systematic review and meta-analysis. Sleep. 2017;40. https://doi.org/10.1093/sleep/zsw032

Tomitani N, Hoshide S, Kario K. Sleep and hypertension - up to date 2024. Hypertens Res. 2024. https://doi.org/10.1038/s41440-024-01845-x.

Article  PubMed  PubMed Central  Google Scholar 

Irwin MR. Sleep and inflammation: partners in sickness and in health. Nat Rev Immunol. 2019;19:702–15. https://doi.org/10.1038/s41577-019-0190-z.

Article  CAS  PubMed  Google Scholar 

Chen Y, Tan F, Wei L, Li X, Lyu Z, Feng X, Wen Y, Guo L, He J, Dai M, Li N. Sleep duration and the risk of cancer: a systematic review and meta-analysis including dose-response relationship. BMC Cancer. 2018;18:1149. https://doi.org/10.1186/s12885-018-5025-y.

Article  PubMed  PubMed Central  Google Scholar 

Antza C, Kostopoulos G, Mostafa S, Nirantharakumar K, Tahrani A. The links between sleep duration, obesity and type 2 diabetes mellitus. J Endocrinol. 2021;252:125–41. https://doi.org/10.1530/JOE-21-0155.

Article  PubMed  PubMed Central  Google Scholar 

Belloir J, Makarem N, Shechter A. Sleep and circadian disturbance in cardiovascular risk. Curr Cardiol Rep. 2022;24:2097–107. https://doi.org/10.1007/s11886-022-01816-z.

Article  PubMed  PubMed Central  Google Scholar 

Mahalakshmi AM, Ray B, Tuladhar S, Bhat A, Bishir M, Bolla SR, Yang J, Essa MM, Chidambaram SB, Guillemin GJ, Sakharkar MK. Sleep, brain vascular health and ageing. Geroscience. 2020;42:1257–83. https://doi.org/10.1007/s11357-020-00235-8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Brzecka A, Leszek J, Ashraf GM, Ejma M, Avila-Rodriguez MF, Yarla NS, Tarasov VV, Chubarev VN, Samsonova AN, Barreto GE, Aliev G. Sleep disorders associated with Alzheimer’s disease: a perspective. Front Neurosci. 2018;12:330. https://doi.org/10.3389/fnins.2018.00330.

Article  PubMed  PubMed Central  Google Scholar 

Miller MA, Wright H, Ji C, Cappuccio FP. Cross-sectional study of sleep quantity and quality and amnestic and non-amnestic cognitive function in an ageing population: the English Longitudinal Study of Ageing (ELSA). PLoS ONE. 2014;9:e100991. https://doi.org/10.1371/journal.pone.0100991.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sabia S, Dugravot A, Leger D, Ben Hassen C, Kivimaki M, Singh-Manoux A. Association of sleep duration at age 50, 60, and 70 years with risk of multimorbidity in the UK: 25-year follow-up of the Whitehall II cohort study. PLoS Med. 2022;19:e1004109. https://doi.org/10.1371/journal.pmed.1004109.

Article  PubMed  PubMed Central  Google Scholar 

Csipo T, Lipecz A, Owens C, Mukli P, Perry JW, Tarantini S, Balasubramanian P, Nyul-Toth A, Yabluchanska V, Sorond FA, Kellawan JM, Purebl G, Sonntag WE, Csiszar A, Ungvari Z, Yabluchanskiy A. Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses. Sci Rep. 2021;11:20994. https://doi.org/10.1038/s41598-021-00188-8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mukli P, Csipo T, Lipecz A, Stylianou O, Racz FS, Owens CD, Perry JW, Tarantini S, Sorond FA, Kellawan JM, Purebl G, Yang Y, Sonntag WE, Csiszar A, Ungvari ZI, Yabluchanskiy A. Sleep deprivation alters task-related changes in functional connectivity of the frontal cortex: a near-infrared spectroscopy study. Brain Behav. 2021;11:e02135. https://doi.org/10.1002/brb3.2135.

Article  PubMed  PubMed Central  Google Scholar 

Krittanawong C, Tunhasiriwet A, Wang Z, Zhang H, Farrell AM, Chirapongsathorn S, Sun T, Kitai T, Argulian E. Association between short and long sleep durations and cardiovascular outcomes: a systematic review and meta-analysis. Eur Heart J Acute Cardiovasc Care. 2019;8:762–70.

Article  PubMed  Google Scholar 

Yin J, Jin X, Shan Z, Li S, Huang H, Li P, Peng X, Peng Z, Yu K, Bao W, Yang W, Chen X, Liu L. Relationship of sleep duration with all-cause mortality and cardiovascular events: a systematic review and dose-response meta-analysis of prospective cohort studies. J Am Heart Assoc. 2017;6. https://doi.org/10.1161/jaha.117.005947

Wang S, Li Z, Wang X, Guo S, Sun Y, Li G, Zhao C, Yuan W, Li M, Li X. Associations between sleep duration and cardiovascular diseases: a meta-review and meta-analysis of observational and Mendelian randomization studies. Front Cardiovasc Med. 2022;9:930000.

Article  PubMed  PubMed Central  Google Scholar 

Li W, Wang D, Cao S, Yin X, Gong Y, Gan Y, Zhou Y, Lu Z. Sleep duration and risk of stroke events and stroke mortality: a systematic review and meta-analysis of prospective cohort studies. Int J Cardiol. 2016;223:870–6.

Article  PubMed  Google Scholar 

Wang H, Sun J, Sun M, Liu N, Wang M. Relationship of sleep duration with the risk of stroke incidence and stroke mortality: an updated systematic review and dose–response meta-analysis of prospective cohort studies. Sleep Med. 2022;90:267–78.

Article  PubMed  Google Scholar 

Huang YM, Xia W, Ge YJ, Hou JH, Tan L, Xu W, Tan CC. Sleep duration and risk of cardio-cerebrovascular disease: a dose-response meta-analysis of cohort studies comprising 3.8 million participants. Front Cardiovasc Med. 2022;9:907990. https://doi.org/10.3389/fcvm.2022.907990

Yang L, Luo Y, He L, Yin J, Li T, Liu S, Li D, Cheng X, Bai Y. Shift work and the risk of cardiometabolic multimorbidity among patients with hypertension: a prospective cohort study of UK Biobank. J Am Heart Assoc. 2022;11:e025936. https://doi.org/10.1161/JAHA.122.025936.

Article  PubMed  PubMed Central  Google Scholar 

Wang N, Sun Y, Zhang H, Wang B, Chen C, Wang Y, Chen J, Tan X, Zhang J, Xia F, Qi L, Lu Y. Long-term night shift work is associated with the risk of atrial fibrillation and coronary heart disease. Eur Heart J. 2021;42:4180–8. https://doi.org/10.1093/eurheartj/ehab505.

Article  CAS  PubMed  Google Scholar 

Kecklund G, Axelsson J. Health consequences of shift work and insufficient sleep. BMJ. 2016;355:i5210. https://doi.org/10.1136/bmj.i5210.

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