5-HT1B/D
serotonin 1B and 1D
A1/A2A
adenosine receptors
ASIC
acid-sensing ion channels
BKCa
large conductance calcium-activated potassium
cAMP
cyclic adenosine monophosphate
CBT
cognitive behavioral therapy
CGAS
candidate gene association study
cGMP
cyclic guanosine monophosphate
CGRP
calcitonin-gene related peptide
CLR
calcitonin-like receptor
CNS
central nervous system
CYP3A4
cytochrome P 450 3A4
EHF
European Headache Federation
FDA
The United States Food and Drug Administration
FHM
familial hemiplegic migraine
GWAS
genome-wide association study
HDL
high density lipoprotein
ICHD-3
The International Classification of Headache Disorders, 3rd edition
KATP
adenosine triphosphate-sensitive potassium
LMICs
low and middle-income countries
MA
episodic migraine with aura
MAF
minor allele frequency
MO
episodic migraine without aura
MOH
medication-overuse headache
NSAID
non-steroidal anti-inflammatory drug
nNOS
neural nitric oxide synthase
OATP
organic anion transporter protein
ODT
orally disintegrating tablet
PACAP
pituitary adenylate cyclase-activating polypeptide
qRT-PCR
quantitative real-time polymerase chain reaction
RAMP1
receptor activity-modifying protein 1
RCT
randomized controlled trial
SNP
single nucleotide polymorphism
TIA
transient ischaemic attack
TRP
transient receptor potential
TRPA1
transient receptor potential ankyrin 1
TRPM8
transient receptor potential cation channel subfamily M member 8
TSHR
thyrotropin-releasing hormone receptor
WES
whole-exome sequencing
WGS
whole-genome sequencing
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